worst performing sandp 500 stocks last 3 years

Moderna (MRNA) has had the lowest return between October 13, 2022 and October 13, 2025 by a US stock in the S&P 500 (GSPC), returning -78.8%.

ASSET DATE % RETURN
Moderna (MRNA)
10/13/2022 - 10/13/2025
-78.77%
Albemarle (ALB)
10/13/2022 - 10/13/2025
-60.49%
Baxter International (BAX)
10/13/2022 - 10/13/2025
-56.2%
Estee Lauder Companies (EL)
10/13/2022 - 10/13/2025
-55.73%
Dollar General (DG)
10/13/2022 - 10/13/2025
-55%
EPAM Systems (EPAM)
10/13/2022 - 10/13/2025
-54.05%
Centene (CNC)
10/13/2022 - 10/13/2025
-51.35%
Devon Energy (DVN)
10/13/2022 - 10/13/2025
-45.27%
Molina Healthcare (MOH)
10/13/2022 - 10/13/2025
-44.15%
Dow (DOW)
10/13/2022 - 10/13/2025
-42.63%
Hormel Foods (HRL)
10/13/2022 - 10/13/2025
-42.13%
Biogen (BIIB)
10/13/2022 - 10/13/2025
-41.81%
Lululemon Athletica (LULU)
10/13/2022 - 10/13/2025
-41.33%
Humana (HUM)
10/13/2022 - 10/13/2025
-40.73%
APA (APA)
10/13/2022 - 10/13/2025
-38.8%
United Parcel Service (UPS)
10/13/2022 - 10/13/2025
-38.65%
Target (TGT)
10/13/2022 - 10/13/2025
-37.61%
Align Technology (ALGN)
10/13/2022 - 10/13/2025
-37.11%
LKQ (LKQ)
10/13/2022 - 10/13/2025
-36.47%
Dollar Tree (DLTR)
10/13/2022 - 10/13/2025
-36.02%
ConAgra Foods (CAG)
10/13/2022 - 10/13/2025
-35.63%
Mosaic (MOS)
10/13/2022 - 10/13/2025
-33.81%
AES (AES)
10/13/2022 - 10/13/2025
-32.47%
Paycom Soft (PAYC)
10/13/2022 - 10/13/2025
-32.46%
Constellation Brands Inc Class A (STZ)
10/13/2022 - 10/13/2025
-31.93%