America Movil SAB de CV ADR (AMX) had the lowest return between 2000 and 2001 by a US stock, returning -100%.

ASSET	YEARS	% RETURN
America Movil SAB de CV ADR (AMX)	2000-2001	-100%
Ammo (POWW)	2000-2001	-99.39%
VirnetX Holding Corp Common Stock (VHC)	2000-2001	-99.16%
Zynex (ZYXI)	2000-2001	-98.83%
Cemtrex (CETX)	2000-2001	-98.55%
Natural Health Trend (NHTC)	2000-2001	-98.29%
Akamai Technologies (AKAM)	2000-2001	-98.27%
Metalla Royalty & Streaming (MTA)	2000-2001	-98.26%
SWK (SWKH)	2000-2001	-98.15%
NetSol Technologies (NTWK)	2000-2001	-98.06%
Lightbridge (LTBR)	2000-2001	-97.92%
NeoGenomics (NEO)	2000-2001	-97.33%
Heritage Global (HGBL)	2000-2001	-97.23%
MicroStrategy (MSTR)	2000-2001	-96.67%
Sify Technologies (SIFY)	2000-2001	-96.38%
eGain (EGAN)	2000-2001	-96.36%
LivePerson (LPSN)	2000-2001	-96.23%
Crexendo (CXDO)	2000-2001	-96.16%
Giga Media (GIGM)	2000-2001	-95.8%
NetEase (NTES)	2000-2001	-95.75%
Precision Optics Corporation, Inc Common stock (POCI)	2000-2001	-95.75%
Gilat Satellite Networks (GILT)	2000-2001	-95.5%
Tucows (TCX)	2000-2001	-95.39%
Widepoint C (WYY)	2000-2001	-94.67%
Vera Therapeutics (VERA)	2000-2001	-94.14%