Since 1999-00, the San Antonio Spurs have the most wins by a team, with 1,278 wins.

Interpreted as:

most team NBA total regular-season wins since 2000

TEAM	W	GP	MIN	PTS	REB	AST	STL	BLK	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TOV	PF	MPG	PPG	RPG	APG	SPG	BPG	TPG
Spurs	1,278	2,013	486,470	206,389	86,871	46,948	14,665	10,996	77,754	166,356	46.7	15,923	43,001	37.0	34,958	46,183	75.7	55.3	20,656	66,215	27,582	38,160	241.7	102.5	43.2	23.3	7.3	5.5	13.7
Mavericks	1,193	2,017	487,480	210,485	85,438	45,007	14,639	9,676	77,889	169,235	46.0	18,357	50,605	36.3	36,350	46,155	78.8	55.5	20,767	64,671	26,154	41,141	241.7	104.4	42.4	22.3	7.3	4.8	13.0
Celtics	1,142	2,013	486,770	206,348	85,058	46,086	16,297	9,382	76,065	166,462	45.7	17,800	49,345	36.1	36,418	47,172	77.2	55.1	20,676	64,382	29,251	43,501	241.8	102.5	42.3	22.9	8.1	4.7	14.5
Heat	1,125	2,015	487,600	200,591	83,967	43,888	15,000	9,790	74,637	162,115	46.0	16,155	45,018	35.9	35,162	46,954	74.9	54.9	19,989	63,978	28,490	41,434	242.0	99.5	41.7	21.8	7.4	4.9	14.1
Lakers	1,110	2,013	486,995	210,481	88,887	46,467	15,049	10,333	78,370	170,196	46.0	16,048	45,881	35.0	37,693	50,976	73.9	54.6	22,750	66,137	28,874	41,247	241.9	104.6	44.2	23.1	7.5	5.1	14.3
Jazz	1,097	2,014	486,410	205,170	86,343	47,129	15,229	10,655	75,704	163,412	46.3	14,810	41,319	35.8	38,952	51,360	75.8	55.2	23,140	63,203	30,494	44,397	241.5	101.9	42.9	23.4	7.6	5.3	15.1
Nuggets	1,092	2,015	486,700	211,291	87,968	48,798	16,011	10,723	78,734	170,522	46.2	15,823	44,688	35.4	38,000	50,538	75.2	54.8	23,440	64,528	29,849	42,910	241.5	104.9	43.7	24.2	7.9	5.3	14.8
Thunder	1,074	2,014	486,960	209,365	87,508	43,673	15,864	10,262	77,697	169,819	45.8	16,274	45,930	35.4	37,697	48,756	77.3	54.7	23,159	64,349	29,434	42,379	241.8	104.0	43.4	21.7	7.9	5.1	14.6
Rockets	1,072	2,014	487,085	207,997	87,183	43,473	15,410	9,664	75,344	167,306	45.0	19,606	55,588	35.3	37,703	49,872	75.6	55.0	22,377	64,806	30,118	41,413	241.8	103.3	43.3	21.6	7.7	4.8	15.0
Pacers	1,063	2,014	486,635	205,644	86,410	45,458	15,379	10,641	76,276	168,004	45.4	16,246	45,157	36.0	36,846	47,547	77.5	54.4	21,511	64,899	29,229	43,093	241.6	102.1	42.9	22.6	7.6	5.3	14.5
Suns	1,060	2,015	486,650	212,430	86,165	47,515	15,465	9,967	79,898	171,513	46.6	17,089	46,953	36.4	35,545	46,084	77.1	55.4	21,823	64,342	29,846	42,813	241.5	105.4	42.8	23.6	7.7	4.9	14.8
Trail Blazers	1,033	2,016	487,390	204,248	85,726	43,591	14,298	9,740	76,048	167,431	45.4	16,670	46,184	36.1	35,482	45,833	77.4	54.4	22,966	62,760	28,390	41,104	241.8	101.3	42.5	21.6	7.1	4.8	14.1
Warriors	1,021	2,007	484,530	213,595	88,028	49,302	16,423	10,591	79,643	173,367	45.9	18,766	50,582	37.1	35,543	46,793	76.0	55.1	23,189	64,839	30,002	43,380	241.4	106.4	43.9	24.6	8.2	5.3	14.9
Bucks	1,021	2,015	487,200	208,217	86,553	46,357	15,229	9,554	77,958	169,713	45.9	16,673	45,941	36.3	35,628	46,822	76.1	54.7	22,102	64,451	28,599	42,276	241.8	103.3	43.0	23.0	7.6	4.7	14.2
Raptors	1,006	2,014	487,135	205,623	84,556	44,733	15,273	9,814	76,385	168,715	45.3	16,440	45,676	36.0	36,413	46,853	77.7	54.3	22,078	62,478	27,204	42,971	241.9	102.1	42.0	22.2	7.6	4.9	13.5
Clippers	1,003	2,014	486,185	205,986	85,995	44,887	14,762	10,491	76,217	165,756	46.0	15,575	42,936	36.3	37,977	50,382	75.4	54.8	21,709	64,286	29,328	42,254	241.4	102.3	42.7	22.3	7.3	5.2	14.6
76ers	985	2,015	487,050	202,734	86,185	45,069	16,891	9,983	75,679	167,306	45.2	14,149	40,417	35.0	37,227	49,189	75.7	53.6	22,578	63,607	29,765	41,893	241.7	100.6	42.8	22.4	8.4	5.0	14.8
Cavaliers	968	2,007	485,155	202,142	86,201	44,548	14,554	9,195	75,219	166,195	45.3	15,730	43,824	35.9	35,974	48,020	74.9	54.0	22,820	63,381	29,179	40,907	241.7	100.7	43.0	22.2	7.3	4.6	14.5
Grizzlies	942	2,015	487,250	201,622	85,068	44,343	16,406	10,504	75,748	167,257	45.3	14,120	40,488	34.9	36,006	47,822	75.3	53.5	22,795	62,273	29,418	42,145	241.8	100.1	42.2	22.0	8.1	5.2	14.6
Kings	929	2,014	487,060	210,766	85,865	45,934	16,049	8,629	78,606	171,260	45.9	16,149	44,833	36.0	37,405	49,098	76.2	54.6	22,031	63,834	29,428	41,744	241.8	104.7	42.6	22.8	8.0	4.3	14.6
Pistons	924	2,008	485,470	199,280	85,297	43,516	14,591	9,745	74,377	166,459	44.7	15,018	42,859	35.0	35,508	47,868	74.2	53.1	23,339	61,958	27,908	41,307	241.8	99.2	42.5	21.7	7.3	4.9	13.9
Bulls	923	2,007	485,905	199,221	87,107	45,243	14,834	9,845	74,994	167,719	44.7	14,435	40,340	35.8	34,798	45,772	76.0	53.0	22,675	64,432	29,709	41,798	242.1	99.3	43.4	22.5	7.4	4.9	14.8
Magic	918	2,015	486,550	203,046	86,163	43,302	14,801	9,612	75,638	167,327	45.2	16,378	46,247	35.4	35,392	47,695	74.2	53.9	21,608	64,555	29,383	41,736	241.5	100.8	42.8	21.5	7.3	4.8	14.6
Nets	909	2,014	486,935	202,184	84,794	45,464	14,644	9,233	74,545	166,258	44.8	16,390	46,342	35.4	36,704	48,162	76.2	53.9	21,444	63,350	29,074	42,597	241.8	100.4	42.1	22.6	7.3	4.6	14.4
Hawks	906	2,009	485,860	203,905	85,109	45,284	15,320	9,670	76,023	167,328	45.4	15,986	44,866	35.6	35,873	46,751	76.7	54.3	22,062	63,047	29,835	41,215	241.8	101.5	42.4	22.5	7.6	4.8	14.9