James Harden has the highest winning percentage by an active player when playing 1,000+ games, winning 65.0 percent of the time.

top career win percentages active players minimum 1000 games

NAME	GP	W%	MPG	PPG	RPG	APG	SPG	BPG	TPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	MIN	PTS	REB	AST	STL	BLK	TOV	PF	+/-
James Harden	1,072	.650	34.7	24.1	5.6	7.1	1.5	0.6	3.7	7.1	16.2	44.1	2.7	7.5	36.4	7.1	8.3	86.1	37,222	25,885	6,017	7,629	1,597	600	3,919	2,695	+4262
LeBron James	1,492	.647	37.9	27.1	7.5	7.4	1.5	0.7	3.5	9.9	19.6	50.6	1.6	4.6	34.8	5.6	7.6	73.6	56,598	40,474	11,185	11,009	2,275	1,111	5,211	2,682	+7443
Chris Paul	1,272	.642	34.1	17.5	4.5	9.4	2.1	0.2	2.3	6.2	13.2	47.1	1.4	3.7	36.9	3.8	4.3	87.0	43,316	22,288	5,682	11,894	2,614	200	2,964	3,034	+6112
Kevin Durant	1,061	.627	36.7	27.3	7.0	4.4	1.1	1.1	3.2	9.4	18.7	50.1	1.9	4.9	38.7	6.6	7.5	88.4	38,972	28,924	7,454	4,645	1,123	1,196	3,363	2,033	+4774
Al Horford	1,078	.617	31.8	13.1	8.0	3.2	0.8	1.2	1.4	5.4	10.6	51.3	0.8	2.1	37.9	1.5	1.9	76.0	34,259	14,167	8,574	3,501	830	1,249	1,523	2,335	+3171
Russell Westbrook	1,162	.584	33.6	21.7	7.1	8.1	1.6	0.3	3.9	7.8	17.8	43.8	1.1	3.6	30.4	5.0	6.5	77.6	39,080	25,211	8,307	9,468	1,849	369	4,587	2,969	+3061
Mike Conley	1,101	.552	31.6	14.4	3.0	5.7	1.4	0.2	1.9	5.1	11.6	43.9	1.6	4.2	38.7	2.6	3.2	82.3	34,840	15,888	3,272	6,306	1,524	228	2,105	2,159	+2449
Kyle Lowry	1,138	.549	31.7	14.3	4.3	6.2	1.3	0.3	2.3	4.6	10.8	42.4	1.9	5.2	36.8	3.2	3.9	81.5	36,021	16,218	4,894	7,003	1,466	340	2,607	3,099	+2906
Nicolas Batum	1,053	.548	29.7	10.4	5.0	3.3	0.9	0.6	1.5	3.7	8.5	43.7	1.6	4.3	36.6	1.4	1.7	83.2	31,268	10,947	5,254	3,464	976	661	1,632	1,838	+1503
DeAndre Jordan	1,055	.547	25.8	8.8	10.0	0.9	0.5	1.5	1.3	3.6	5.3	67.4	0.0	0.0	15.4	1.7	3.5	47.5	27,176	9,274	10,501	992	555	1,540	1,402	2,610	+1071
DeMar DeRozan	1,110	.515	34.7	21.2	4.4	4.1	1.0	0.3	2.0	7.6	16.2	46.9	0.5	1.6	29.6	5.6	6.6	84.1	38,462	23,582	4,910	4,527	1,108	361	2,274	2,509	+93
Brook Lopez	1,025	.496	30.2	16.1	6.2	1.4	0.6	1.9	1.6	6.1	12.4	49.6	0.9	2.6	34.9	2.9	3.6	79.6	30,976	16,476	6,336	1,471	583	1,912	1,667	2,697	+854
Jeff Green	1,185	.489	27.7	12.0	4.1	1.5	0.6	0.5	1.3	4.3	9.7	45.0	1.0	2.9	33.7	2.4	2.9	80.4	32,861	14,241	4,825	1,764	753	587	1,573	2,470	-1798
Rudy Gay	1,120	.456	30.9	15.8	5.6	2.0	1.1	0.7	2.0	6.0	13.2	45.2	1.1	3.1	34.6	2.8	3.5	79.9	34,561	17,642	6,283	2,280	1,231	798	2,245	2,524	-142
Thaddeus Young	1,172	.444	28.2	12.1	5.6	1.8	1.4	0.4	1.4	5.2	10.4	50.3	0.4	1.4	32.8	1.2	1.8	66.1	33,012	14,225	6,613	2,135	1,612	458	1,641	2,486	-274