Between the 2015-16 and 2021-22 seasons, Stephen Curry had the highest plus/minus, at +3917.

Interpreted as:

best +- by a player 2015-16 to 2021-22

	NAME	+/-	GP	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	PTS	REB	AST	STL	BLK	TOV	PF
1	Stephen Curry S. Curry	+3917	410	33.7	27.7	5.2	6.2	1.6	0.2	9.2	19.3	47.6	4.7	11.2	42.0	4.6	5.0	91.4	64.3	0.7	4.5	3.1	13,801	11,350	2,119	2,522	650	98	1,281	884
2	Chris Paul C. Paul	+3029	456	32.0	17.3	4.7	8.8	1.8	0.2	6.1	13.0	47.2	1.7	4.7	37.3	3.3	3.7	89.3	59.2	0.5	4.2	2.4	14,591	7,876	2,136	4,027	812	103	1,091	1,076
3	Kevin Durant K. Durant	+2906	370	34.8	27.0	7.3	5.5	0.9	1.3	9.5	18.2	52.0	2.2	5.6	39.0	5.9	6.6	89.1	64.0	0.5	6.8	3.1	12,879	9,989	2,717	2,030	316	484	1,131	725
4	Draymond Green D. Green	+2904	445	31.8	9.7	7.7	7.3	1.5	1.2	3.5	7.8	45.3	0.9	2.8	31.3	1.7	2.4	72.1	54.7	1.1	6.6	2.8	14,164	4,301	3,434	3,237	688	515	1,239	1,279
5	Rudy Gobert R. Gobert	+2749	484	32.5	14.1	12.8	1.4	0.7	2.3	5.2	7.8	66.2	0.0	0.0	0.0	3.7	5.8	64.3	67.9	3.5	9.3	1.8	15,709	6,802	6,189	691	340	1,127	865	1,347
6	Klay Thompson K. Thompson	+2449	341	33.5	21.4	3.8	2.3	0.8	0.5	8.1	17.3	46.8	3.3	8.0	41.6	1.9	2.2	85.3	58.5	0.5	3.3	1.6	11,414	7,306	1,292	785	281	187	552	619
7	Kawhi Leonard K. Leonard	+2387	324	33.1	24.7	6.6	3.8	1.8	0.7	8.6	17.5	49.2	1.9	4.9	39.1	5.5	6.3	87.4	60.7	1.1	5.5	2.0	10,724	7,988	2,143	1,215	569	213	650	546
8	Kyle Lowry K. Lowry	+2192	447	35.0	17.7	5.0	7.3	1.4	0.4	5.6	13.0	43.2	2.8	7.3	38.2	3.7	4.4	83.7	59.2	0.7	4.3	2.8	15,650	7,932	2,218	3,257	616	160	1,235	1,249
9	Giannis Antetokounmpo G. Antetokounmpo	+2167	498	34.0	25.6	10.6	5.3	1.3	1.4	9.3	17.1	54.5	0.8	2.8	28.7	6.2	8.7	71.8	61.3	1.9	8.7	3.2	16,916	12,766	5,268	2,663	631	710	1,589	1,542
10	Nikola Jokić N. Jokić	+2153	527	30.4	19.7	10.4	6.2	1.2	0.7	7.6	13.9	54.2	1.0	2.9	34.5	3.5	4.3	83.0	62.2	2.6	7.7	2.8	16,008	10,364	5,456	3,281	627	376	1,462	1,467
11	Danny Green D. Green	+2151	496	25.9	8.2	3.5	1.6	1.1	0.8	2.9	7.1	40.8	1.9	4.9	38.7	0.4	0.6	77.2	55.3	0.6	2.9	1.0	12,848	4,057	1,735	774	522	379	475	920
12	Jayson Tatum J. Tatum	+2033	365	33.4	20.9	6.6	3.0	1.1	0.7	7.5	16.4	45.6	2.3	5.9	38.3	3.7	4.4	84.4	57.1	0.9	5.8	2.1	12,184	7,640	2,420	1,106	410	252	779	770
13	James Harden J. Harden	+1996	490	36.7	29.8	6.9	9.0	1.6	0.7	8.8	19.9	44.1	3.5	9.8	35.7	8.7	10.1	86.3	61.1	0.9	6.0	4.7	18,001	14,591	3,361	4,389	804	326	2,309	1,336
14	LeBron James L. James	+1931	455	36.0	26.7	8.1	8.2	1.3	0.7	10.1	19.3	52.3	1.9	5.5	35.1	4.6	6.5	70.6	60.3	1.1	7.0	3.8	16,371	12,149	3,708	3,744	583	317	1,721	816
15	Steven Adams S. Adams	+1899	513	28.9	10.4	8.7	1.7	1.0	0.9	4.4	7.4	59.5	0.0	0.0	8.3	1.7	3.1	55.0	60.0	4.0	4.7	1.5	14,841	5,355	4,448	873	510	486	780	1,225
16	Paul George P. George	+1858	445	35.0	23.8	6.7	4.0	1.8	0.4	8.0	18.3	43.9	3.1	7.8	39.1	4.7	5.5	85.7	57.6	0.9	5.8	3.0	15,557	10,588	2,974	1,802	799	186	1,332	1,202
17	Joel Embiid J. Embiid	+1856	328	31.2	26.0	11.4	3.3	0.9	1.7	8.5	17.4	49.0	1.2	3.5	33.8	7.8	9.6	81.0	60.1	2.3	9.0	3.4	10,241	8,535	3,732	1,080	285	542	1,109	1,010
18	Khris Middleton K. Middleton	+1800	463	33.2	19.3	5.3	4.5	1.2	0.2	6.9	15.0	46.0	2.1	5.4	38.9	3.4	3.8	88.5	57.8	0.6	4.7	2.4	15,378	8,926	2,459	2,082	574	88	1,115	1,187
19	Joe Ingles J. Ingles	+1736	511	26.4	9.2	3.4	4.0	0.9	0.2	3.2	7.2	45.3	2.0	4.7	41.3	0.7	1.0	76.9	60.5	0.3	3.1	1.6	13,484	4,698	1,739	2,031	472	80	829	975
20	Pascal Siakam P. Siakam	+1621	400	29.5	15.7	6.3	3.1	0.9	0.7	6.0	12.3	48.9	1.0	3.0	32.8	2.7	3.5	77.4	56.8	1.4	4.9	1.8	11,780	6,290	2,522	1,241	371	271	713	1,085
21	Andre Iguodala A. Iguodala	+1580	388	23.9	5.9	3.8	3.1	0.9	0.6	2.3	4.8	46.9	0.7	2.3	32.4	0.7	1.1	63.8	56.3	0.7	3.1	1.0	9,290	2,299	1,464	1,213	362	225	377	552
22	JJ Redick	+1575	403	27.5	15.4	2.2	2.0	0.5	0.1	5.1	11.3	45.2	2.7	6.3	42.7	2.5	2.8	89.6	61.3	0.2	2.0	1.2	11,096	6,213	889	802	194	54	491	658
23	Kyrie Irving K. Irving	+1472	355	33.7	24.5	4.0	5.8	1.3	0.4	9.1	19.0	48.0	2.6	6.5	39.5	3.7	4.2	89.9	58.9	0.8	3.2	2.5	11,972	8,714	1,436	2,057	451	157	870	827
24	Al Horford A. Horford	+1464	454	30.6	13.1	7.1	4.0	0.8	1.2	5.3	10.9	48.6	1.3	3.6	36.1	1.2	1.5	80.2	56.6	1.6	5.5	1.4	13,886	5,950	3,223	1,818	348	550	630	885
25	Jrue Holiday J. Holiday	+1447	467	33.4	18.2	4.3	6.6	1.5	0.6	7.1	15.0	47.4	1.7	4.7	35.8	2.3	3.0	76.9	55.8	0.9	3.4	2.7	15,581	8,513	2,020	3,105	723	298	1,278	1,006