Dwyane Wade averaged 26.2 points, 6.4 assists and 5.2 rebounds in 535 games between the 2004-05 and 2011-12 seasons.
| NAME | SEASON | TM | GP | MPG | PPG | RPG | APG | SPG | BPG | FGM | FGA | FG% | 3PM | 3PA | 3P% | FTM | FTA | FT% | TS% | OREB | DREB | TPG | MIN | PTS | REB | AST | STL | BLK | TOV | PF | +/- | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | D. Wade | 2004-05 | 77 | 38.6 | 24.1 | 5.2 | 6.8 | 1.6 | 1.1 | 8.2 | 17.1 | 47.8 | 0.2 | 0.6 | 28.9 | 7.5 | 9.9 | 76.2 | 56.1 | 1.4 | 3.7 | 4.2 | 2,974 | 1,854 | 397 | 520 | 121 | 82 | 321 | 230 | +397 | |
| 2 | | D. Wade | 2005-06 | 75 | 38.6 | 27.2 | 5.7 | 6.7 | 1.9 | 0.8 | 9.3 | 18.8 | 49.5 | 0.2 | 1.0 | 17.1 | 8.4 | 10.7 | 78.3 | 57.7 | 1.4 | 4.3 | 3.6 | 2,892 | 2,040 | 430 | 503 | 146 | 58 | 268 | 217 | +485 | |
| 3 | | D. Wade | 2006-07 | 51 | 37.9 | 27.4 | 4.7 | 7.5 | 2.1 | 1.2 | 9.3 | 18.9 | 49.1 | 0.4 | 1.5 | 26.6 | 8.5 | 10.5 | 80.7 | 58.3 | 1.0 | 3.7 | 4.2 | 1,931 | 1,397 | 239 | 384 | 107 | 62 | 216 | 117 | +96 | |
| 4 | | D. Wade | 2007-08 | 51 | 38.3 | 24.6 | 4.2 | 6.9 | 1.7 | 0.7 | 8.6 | 18.4 | 46.9 | 0.4 | 1.5 | 28.6 | 6.9 | 9.2 | 75.8 | 54.9 | 0.9 | 3.3 | 4.4 | 1,954 | 1,254 | 214 | 354 | 87 | 37 | 224 | 137 | -255 | |
| 5 | | D. Wade | 2008-09 | 79 | 38.6 | 30.2 | 5.0 | 7.5 | 2.2 | 1.3 | 10.8 | 22.0 | 49.1 | 1.1 | 3.5 | 31.7 | 7.5 | 9.8 | 76.5 | 57.4 | 1.1 | 3.9 | 3.4 | 3,048 | 2,386 | 398 | 589 | 173 | 106 | 272 | 178 | +216 | |
| 6 | | D. Wade | 2009-10 | 77 | 36.3 | 26.6 | 4.8 | 6.5 | 1.8 | 1.1 | 9.3 | 19.6 | 47.6 | 0.9 | 3.2 | 30.0 | 6.9 | 9.1 | 76.1 | 56.2 | 1.4 | 3.5 | 3.3 | 2,792 | 2,045 | 373 | 501 | 142 | 82 | 252 | 181 | +353 | |
| 7 | | D. Wade | 2010-11 | 76 | 37.1 | 25.5 | 6.4 | 4.6 | 1.5 | 1.1 | 9.1 | 18.2 | 50.0 | 0.8 | 2.7 | 30.6 | 6.5 | 8.6 | 75.8 | 58.1 | 1.6 | 4.8 | 3.1 | 2,823 | 1,941 | 485 | 346 | 111 | 87 | 237 | 197 | +572 | |
| 8 | | D. Wade | 2011-12 | 49 | 33.2 | 22.1 | 4.8 | 4.6 | 1.7 | 1.3 | 8.5 | 17.1 | 49.7 | 0.3 | 1.1 | 26.8 | 4.8 | 6.1 | 79.1 | 55.9 | 1.5 | 3.3 | 2.6 | 1,625 | 1,082 | 237 | 225 | 82 | 63 | 129 | 110 | +344 | |
| Average | 66.9 | 37.5 | 26.2 | 5.2 | 6.4 | 1.8 | 1.1 | 9.2 | 18.9 | 48.7 | 0.6 | 2.0 | 29.1 | 7.2 | 9.3 | 77.1 | 56.9 | 1.3 | 3.9 | 3.6 | 2504.9 | 1749.9 | 346.6 | 427.8 | 121.1 | 72.1 | 239.9 | 170.9 | 276.0 | ||||
| Total | 535 | 37.5 | 26.2 | 5.2 | 6.4 | 1.8 | 1.1 | 9.2 | 18.9 | 48.7 | 0.6 | 2.0 | 29.1 | 7.2 | 9.3 | 77.1 | 56.9 | 1.3 | 3.9 | 3.6 | 20,039 | 13,999 | 2,773 | 3,422 | 969 | 577 | 1,919 | 1,367 | +2208 |
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