Wilt Chamberlain had the most games with 41+ points, with 253 games.

Interpreted as:

most regular-season game by a player with 41+ points

	NAME	GP	PTS	MPG	PPG	RPG	APG	SPG	BPG	FGM	FGA	FG%	3PM	3PA	3P%	FTM	FTA	FT%	TS%	OREB	DREB	TPG	MIN	REB	AST	STL	BLK	TOV	PF	+/-
1	Wilt Chamberlain W. Chamberlain	253	12,738		50.3	25.8				20.5	37.9	54.1				9.3	16.3	57.4	55.9					6,536					461
2	Michael Jordan M. Jordan	139	6,453	41.2	46.4	6.4	5.0	2.9	1.1	17.5	30.1	58.0	0.8	2.1	37.5	10.7	12.4	86.7	65.3	1.9	4.5	2.7	5,728	890	698	400	152	378	392	+217
3	Kobe Bryant K. Bryant	96	4,461	42.9	46.5	5.9	4.1	1.8	0.6	16.0	31.3	51.0	3.1	7.1	44.0	11.4	13.4	85.4	62.5	1.1	4.8	3.2	4,123	567	392	168	54	306	258	+626
4	James Harden J. Harden	84	3,918	39.7	46.6	7.3	7.8	2.3	0.7	13.6	26.9	50.6	5.8	13.2	44.3	13.5	15.4	88.0	69.2	1.2	6.1	4.9	3,332	615	652	189	62	414	250	+854
5	Elgin Baylor E. Baylor	72	3,355		46.6					17.6						11.3	14.2	79.7											248
6	LeBron James L. James	66	2,997	41.9	45.4	8.6	7.0	1.8	0.9	16.0	27.1	59.0	3.8	7.5	50.2	9.7	12.3	78.5	69.8	1.5	7.1	3.5	2,763	567	459	118	59	230	128	+546
7	Allen Iverson A. Iverson	63	2,867	45.0	45.5	4.3	6.0	2.4	0.2	15.9	31.0	51.1	2.1	5.0	41.5	11.7	14.0	83.5	61.2	1.0	3.3	3.7	2,835	273	377	151	13	232	148	+386
8	Rick Barry R. Barry	61	2,805	43.0	46.0	8.5	5.3	2.9		17.6	33.8	52.2				10.7	11.9	90.3	59.0			3.2	2,621	519	326	82		19	200
9	Stephen Curry S. Curry	59	2,737	36.5	46.4	5.4	5.6	1.4	0.3	15.2	25.9	58.5	8.8	15.5	56.8	7.3	7.9	92.5	78.9	0.7	4.6	3.2	2,155	316	332	81	18	191	119	+728
10	George Gervin G. Gervin	58	2,582	40.0	44.5	4.9	2.9	1.3	0.9	17.4	29.0	60.2	0.4	0.9	37.8	9.3	10.9	85.3	65.9				2,321	286	168	78	55		150
11	Kevin Durant K. Durant	55	2,463	41.6	44.8	8.0	4.9	1.2	1.1	15.2	26.7	56.9	4.0	8.2	48.9	10.5	11.7	89.1	70.3	0.7	7.3	3.8	2,287	439	272	65	63	210	127	+301
12	Jerry West J. West	55	2,451		44.6					16.3						12.1	14.2	84.8
13	Oscar Robertson O. Robertson	55	2,408		43.8	9.9	11.0			15.5						12.8	14.6	87.6						545	606				193
14	Kareem Abdul-Jabbar K. Abdul-Jabbar	54	2,433		45.1	16.2	4.4		3.5	18.0			0.0	0.0		9.1	12.2	74.1						877	235		56
15	Dominique Wilkins D. Wilkins	50	2,253	41.2	45.1	7.7	3.1	1.9	0.6	16.4	29.1	56.6	1.3	2.4	52.5	10.9	12.7	86.1	65.0	3.3	4.3	3.0	2,060	383	155	94	32	152	96
16	Bob McAdoo B. McAdoo	48	2,118		44.1	15.6				17.2	28.1	61.2				9.7	12.2	79.4	65.8					748
17	Damian Lillard D. Lillard	47	2,193	39.5	46.7	5.0	7.1	1.1	0.4	14.6	26.0	56.1	6.7	13.1	50.8	10.9	11.7	92.9	75.0	0.6	4.4	2.7	1,856	234	336	54	17	127	88	+341
18	Giannis Antetokounmpo G. Antetokounmpo	46	2,113	36.5	45.9	13.1	5.2	1.2	1.2	16.8	25.4	66.0	1.4	3.6	39.5	11.0	15.2	72.1	71.5	2.7	10.3	3.2	1,680	602	241	56	54	148	132	+369
19	Luka Dončić L. Dončić	41	1,862	38.8	45.4	9.7	9.1	1.7	0.4	15.5	26.4	58.7	4.9	10.5	47.0	9.5	12.2	77.6	71.4	0.9	8.9	3.7	1,589	398	375	69	17	152	109	+420
20	Joel Embiid J. Embiid	40	1,814	36.3	45.4	13.1	4.3	1.3	2.2	15.2	24.7	61.7	1.3	3.5	37.1	13.6	15.6	87.2	71.9	2.9	10.2	3.2	1,452	522	173	51	87	129	126	+503
21	Russell Westbrook R. Westbrook	40	1,812	39.0	45.3	9.9	8.2	1.6	0.3	15.8	30.2	52.4	3.2	7.8	40.7	10.5	12.7	82.7	63.4	1.9	8.0	5.0	1,560	396	328	65	13	198	112	+71
22	Adrian Dantley A. Dantley	39	1,751	42.3	44.9	6.9	4.4		0.1	16.2	23.8	68.0	0.0	0.1	33.3	12.5	14.6	85.4	74.2				1,648	268	170		4		127
23	Tracy McGrady T. McGrady	37	1,667	41.9	45.1	7.6	5.1	1.6	0.9	16.1	29.7	54.1	3.6	7.8	46.7	9.2	12.1	76.2	64.2	1.7	5.9	2.8	1,549	282	190	61	35	103	73	+211
24	Larry Bird L. Bird	36	1,637	42.4	45.5	10.9	6.0	1.9	1.0	17.6	29.3	60.1	1.6	3.3	47.1	8.8	9.4	93.2	68.1	2.3	8.6	3.4	1,527	391	216	68	36	124	85
25	Bernard King B. King	36	1,643	41.8	45.6	8.4	3.8			17.4	28.4	61.2	0.1	0.4	23.1	10.8	13.9	78.2	66.2				1,503	303	135				119