The 2021 roster for the 49ers included Jimmy Garoppolo at quarterback, Kyle Juszczyk at running back, Brandon Aiyuk at wide receiver, George Kittle at tight end and Daniel Brunskill at offensive lineman.
| NO. | NAME | POS | HEIGHT | WEIGHT | DOB | AGE | COLLEGE | ||
|---|---|---|---|---|---|---|---|---|---|
| 1 | 0 |  | T. Adams | LB | 6'2" | 230 | 4/11/1992 | 29 | West Georgia |
| 2 | 11 |  | B. Aiyuk | WR | 6'1" | 206 | 3/17/1998 | 23 | Arizona State |
| 3 | 51 | | A. Al-Shaair | LB | 6'2" | 228 | 8/4/1997 | 24 | Florida Atlantic |
| 4 | 91 | | A. Armstead | DL | 6'7" | 290 | 11/15/1993 | 28 | Oregon |
| 5 | 65 | | A. Banks | OL | 6'5" | 325 | 9/3/1997 | 24 | Notre Dame |
| 6 | 64 | | A. Barrett | DL | 6'3" | 260 | 3/6/1994 | 27 | San Diego State |
| 7 | 17 | | T. Benjamin | WR | 5'10" | 175 | 12/29/1989 | 32 | Miami (FL) |
| 8 | 97 |  | N. Bosa | DL | 6'4" | 266 | 10/23/1997 | 24 | Ohio State |
| 9 | 64 | | J. Brendel | OL | 6'4" | 299 | 9/10/1992 | 29 | UCLA |
| 10 | 60 | | D. Brunskill | OL | 6'5" | 300 | 1/27/1994 | 27 | San Diego State |
| 11 | 49 | | T. Cannon | RB | 5'11" | 185 | 7/23/1994 | 27 | Virginia State |
| 12 | 66 | | T. Compton | OL | 6'6" | 315 | 5/10/1989 | 32 | South Dakota |
| 13 | 13 | | R. Cracraft | WR | 6'0" | 198 | 11/1/1994 | 27 | Washington State |
| 14 | 67 | | D. Daniels | DL | 6'4" | 325 | 12/4/1997 | 24 | Nebraska |
| 15 | 43 | | D. Dennard | DB | 5'11" | 200 | 10/10/1991 | 30 | Michigan State |
| 16 | 82 | | R. Dwelley | TE | 6'5" | 235 | 1/26/1995 | 26 | San Diego |
| 17 | 56 | | S. Ebukam | DL | 6'3" | 245 | 5/9/1995 | 26 | Eastern Washington |
| 18 | 45 | | D. Flannigan-Fowles | LB | 6'2" | 209 | 9/4/1996 | Arizona | |
| 19 | 55 | | D. Ford | DL | 6'2" | 252 | 3/19/1991 | 30 | Auburn |
| 20 | 10 |  | J. Garoppolo | QB | 6'2" | 225 | 11/2/1991 | 30 | Eastern Illinois |
| 21 | 90 | | K. Givens | DL | 6'1" | 285 | 3/1/1997 | 24 | Penn State |
| 22 | 9 | | R. Gould | K | 6'0" | 190 | 12/6/1982 | 39 | Penn State |
| 23 | 57 | | D. Greenlaw | LB | 6'0" | 230 | 5/25/1997 | 24 | Arkansas |
| 24 | 77 | | A. Gutierrez | OL | 6'8" | 341 | 12/29/1995 | ||
| 25 | 61 | | J. Halapio | OL | 6'4" | 315 | 6/23/1991 | 30 | Florida |
More NFL News
Bears hit by running back injuries as D’Andre Swift exits practice and Kyle Monangai is week to week
Ex-Fox Sports analyst Mark Sanchez plans guilty plea to charges stemming from fight outside hotel
Cardinals wide receiver Michael Wilson signs a 3-year, $75M contract extension, AP source says
Khosla family closes purchase of reigning Super Bowl champion Seahawks for $9.6 billion
Alphonso Smith, 2-time All-America DB who played in the NFL for 4 seasons, dies at 40
Tutu Atwell returns to Rams to chase another Super Bowl ring after he thought their book was closed
More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |