The San Francisco 49ers were 10-7 in 2021. They finished 3rd in the NFC West and 6th in the NFC. They fell to the Los Angeles Rams, 20 to 17, in the 2021 NFC Championship game.
Scores & Schedules
See schedule
LAR 
DAL 
HOU 
Cardinals 2021 Stats
See stats| GP | PTS | YDS | PLY | AVG | RUSH YDS | RUSH ATT | RUSH AVG | PASS YDS | PASS ATT | PASS AVG | SCK | SCKY | 1DWN | RUSH 1DWN | PASS 1DWN | PEN 1DWN | PEN | PEN YDS | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Team | 17 | 427 | 6,387 | 1,046 | 6.1 | 2,166 | 499 | 4.3 | 4,437 | 514 | 8.6 | 33 | 216 | 361 | 130 | 200 | 31 | 102 | 1,066 |
Team Rank | 13th | 7th | 25th | 1st | 7th | 5th | 16th | 12th | 29th | 2nd | 11th | 24th | 11th | 8th | 15th | 16th | 13th | 30th | |
Opponent | 17 | 365 | 5,270 | 1,032 | 5.1 | 1,760 | 439 | 4.0 | 3,874 | 545 | 7.1 | 48 | 364 | 318 | 97 | 180 | 41 | 94 | 793 |
Opponent Rank | 9th | 3rd | 5th | 6th | 7th | 14th | 7th | 7th | 7th | 17th | 5th | 29th | 6th | 5th | 5th | 32nd | 22nd | 26th | |
Net | +62 | +1,117 | +14 | +1.0 | +406 | +60 | +0.3 | +563 | -31 | +1.5 | -15 | -148 | +43 | +33 | +20 | -10 | +8 | +273 | |
Net Rank | 12th | 3rd | 14th | 2nd | 6th | 7th | 8th | 8th | 24th | 1st | 5th | 31st | 7th | 5th | 8th | 28th | 19th | 32nd |
Gallery
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 1 | 0 | .800 |
 Commanders | 3 | 2 | 0 | .600 |
| NFC North | W | L | T | PCT |
 Lions | 4 | 1 | 0 | .800 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 4 | 1 | 0 | .800 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
 49ers | 4 | 1 | 0 | .800 |
 Seahawks | 3 | 2 | 0 | .600 |
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