The San Francisco 49ers have a 14-14-2 record against the spread against the Cardinals at home all-time.
Showing
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/14/1980 | 0-0-1 | vs | W 24-21 | -3 | 0 (P) | 42 | +3 (O) | 3 | 19 | 392 | 342 | ||||||
| 2 | | 49ers | 11/9/1986 | 1-0 | vs | W 43-17 | -11 | +15 (Y) | 40.5 | +19.5 (O) | 5 | 23 | 460 | 364 | ||||||
| 3 | | 49ers | 10/18/1987 | vs | W 34-28 | 5 | 28 | 448 | 324 | |||||||||||
| 4 | | 49ers | 11/17/1991 | 0-1 | vs | W 14-10 | -11.5 | -7.5 (N) | 32 | -8 (U) | 2 | 22 | 257 | 176 | 60.0 | |||||
| 5 | | 49ers | 10/24/1993 | 1-0 | vs | W 28-14 | -11.5 | +2.5 (Y) | 43 | -1 (U) | 4 | 26 | 428 | 429 | 50.0 | |||||
| 6 | | 49ers | 10/1/2000 | 1-0 | vs | W 27-20 | -3.5 | +3.5 (Y) | 47 | 0 (P) | 3 | 18 | 345 | 365 | 43.8 | |||||
| 7 | | 49ers | 10/27/2002 | 1-0 | vs | W 38-28 | -8 | +2 (Y) | 40.5 | +25.5 (O) | 5 | 18 | 357 | 420 | 50.0 | 100.0 | ||||
| 8 | | 49ers | 12/7/2003 | 1-0 | vs | W 50-14 | -10 | +26 (Y) | 41 | +23 (O) | 7 | 30 | 496 | 210 | 50.0 | 0.0 | ||||
| 9 | | 49ers | 10/10/2004 | 1-0 | vs | W 31-28 | -1 | +2 (Y) | 36.5 | +22.5 (O) | 3 | 28 | 448 | 320 | 40.0 | 100.0 | ||||
| 10 | | 49ers | 12/4/2005 | 0-1 | vs | L 10-17 | +3 | -4 (N) | 44.5 | -17.5 (U) | 1 | 11 | 220 | 404 | 22.2 | |||||
| 11 | | 49ers | 12/24/2006 | 0-1 | -185 | vs | +165 | L 20-26 | -4 | -10 (N) | 45 | +1 (O) | 2 | 14 | 223 | 372 | 22.2 | 100.0 | ||
| 12 | | 49ers | 9/10/2007 | 0-0-1 | -195 | vs | +170 | W 20-17 | -3 | 0 (P) | 45 | -8 (U) | 2 | 16 | 194 | 261 | 25.0 | 100.0 | ||
| 13 | | 49ers | 9/7/2008 | 0-1 | +115 | vs | -135 | L 13-23 | +2.5 | -7.5 (N) | 41.5 | -5.5 (U) | 1 | 13 | 291 | 285 | 37.5 | |||
| 14 | | 49ers | 12/14/2009 | 1-0 | +185 | vs | -225 | W 24-9 | +3 | +18 (Y) | 44.5 | -11.5 (U) | 3 | 18 | 327 | 245 | 50.0 | |||
| 15 | | 49ers | 1/2/2011 | 1-0 | -250 | vs | +210 | W 38-7 | -6.5 | +24.5 (Y) | 39 | +6 (O) | 5 | 16 | 362 | 279 | 18.2 | |||
| 16 | | 49ers | 11/20/2011 | 1-0 | -600 | vs | +450 | W 23-7 | -10 | +6 (Y) | 41 | -11 (U) | 2 | 25 | 431 | 229 | 38.1 | 100.0 | ||
| 17 | | 49ers | 12/30/2012 | 0-1 | -1600 | vs | +1000 | W 27-13 | -16.5 | -2.5 (N) | 38.5 | +1.5 (O) | 3 | 20 | 407 | 262 | 28.6 | 100.0 | ||
| 18 | | 49ers | 10/13/2013 | 1-0 | -550 | vs | +400 | W 32-20 | -10 | +2 (Y) | 40.5 | +11.5 (O) | 3 | 20 | 387 | 403 | 28.6 | 100.0 | ||
| 19 | | 49ers | 12/28/2014 | 0-1 | -300 | vs | +240 | W 20-17 | -6 | -3 (N) | 38 | -1 (U) | 2 | 18 | 395 | 397 | 41.7 | |||
| 20 | | 49ers | 11/29/2015 | 1-0 | +350 | vs | -430 | L 13-19 | +8 | +2 (Y) | 45 | -13 (U) | 1 | 17 | 368 | 337 | 0.0 | 50.0 | ||
| 21 | | 49ers | 10/6/2016 | 0-1 | +170 | vs | -189 | L 21-33 | +3.5 | -8.5 (N) | 42.5 | +11.5 (O) | 3 | 25 | 286 | 288 | 28.6 | 100.0 | ||
| 22 | | 49ers | 11/5/2017 | 0-1 | +118 | vs | -128 | L 10-20 | +2.5 | -7.5 (N) | 39.5 | -9.5 (U) | 1 | 17 | 329 | 368 | 35.3 | 0.0 | ||
| 23 | | 49ers | 10/7/2018 | 0-1 | -156 | vs | +146 | L 18-28 | -3 | -13 (N) | 40.5 | +5.5 (O) | 3 | 33 | 447 | 220 | 58.8 | 50.0 | ||
| 24 | | 49ers | 11/17/2019 | 1-0 | -470 | vs | +351 | W 36-26 | -9.5 | +0.5 (Y) | 44 | +18 (O) | 5 | 26 | 442 | 266 | 46.2 | 0.0 | ||
| 25 | | 49ers | 9/13/2020 | 0-1 | -312 | vs | +245 | L 20-24 | -6.5 | -10.5 (N) | 48 | -4 (U) | 2 | 18 | 366 | 404 | 18.2 | 0.0 | ||
| Average | 1.6 | 3.1 | 21.2 | 365.3 | 322.8 | |||||||||||||||
| Total | 14-14-2 | 96 | 656 | 11,325 | 10,007 | |||||||||||||||
SF
STL
PHX
ARIMore NFL News
Ja'Marr Chase's halftime talk sparks Bengals' comeback win over Ravens
Raiders coach Klint Kubiak shuts down QB talk. Kirk Cousins remains the starter
Saints enter a pivotal 'self-scout' week as they try to avoid a 6th straight non-playoff season
Banged-up 49ers limp into their bye week after a 29-20 loss to the Falcons
Lions' Dan Campbell says his trust in Jared Goff enabled him to take a huge 4th-down gamble
Stuck in a 10-game home losing streak, Cardinals are bleeding fan support and looking for answers
More 49ers Stats
Team Leaders 
PASS
1,748
Purdy
RUSH
389
McCaffrey
REC
425
Kittle
Team Rankings
PPG
28.1
3rd
OPP PPG
19.9
6th
RUSH YDS/G
127.4
8th
PASS YDS/G
249.7
12th
Seahawks
Rams
LV
DAL
MIN
NYG
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
4 | 2 | 1 | .643 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
1 | 4 | 1 | .250 | |
| NFC North | W | L | T | PCT |
6 | 0 | 0 | 1.000 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| NFC South | W | L | T | PCT |
3 | 3 | 0 | .500 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
| NFC West | W | L | T | PCT |
6 | 1 | 0 | .857 | |
4 | 3 | 0 | .571 | |
3 | 4 | 0 | .429 | |
2 | 5 | 0 | .286 |
Eagles
Commanders
Bears
Lions
Packers
Panthers
Falcons
Buccaneers
Saints| AFC East | W | L | T | PCT |
|---|---|---|---|---|
5 | 1 | 0 | .833 | |
4 | 3 | 0 | .571 | |
2 | 5 | 0 | .286 | |
1 | 5 | 0 | .167 | |
| AFC North | W | L | T | PCT |
5 | 2 | 0 | .714 | |
5 | 2 | 0 | .714 | |
4 | 2 | 0 | .667 | |
4 | 3 | 0 | .571 | |
| AFC South | W | L | T | PCT |
4 | 2 | 0 | .667 | |
2 | 5 | 0 | .286 | |
2 | 5 | 0 | .286 | |
1 | 6 | 0 | .143 | |
| AFC West | W | L | T | PCT |
5 | 1 | 0 | .833 | |
5 | 2 | 0 | .714 | |
3 | 4 | 0 | .429 | |
0 | 6 | 0 | .000 |
Bills
Patriots
Jets
Dolphins
Browns
Steelers
Bengals
Ravens
Jaguars
Colts
Texans
Titans
Chiefs
Broncos
Chargers