The San Francisco 49ers had a record of 28-28-1 against the spread against the NFC West at home from 2003 through 2021.

	TEAM	DATE	ATS	TM			OPP		RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	11/2/2003	1-0	SF		vs	STL		W 30-10	+5	+25 (Y)	44	-4 (U)	4	24	389	340	69.2
2	49ers	12/7/2003	1-0	SF		vs	ARI		W 50-14	-10	+26 (Y)	41	+23 (O)	7	30	496	210	50.0	0.0
3	49ers	12/27/2003	0-1	SF		vs	SEA		L 17-24	-1	-8 (N)	46	-5 (U)	2	14	290	394	28.6	0.0
4	49ers	10/3/2004	0-1	SF		vs	STL		L 14-24	+3.5	-6.5 (N)	45	-7 (U)	2	26	332	360	58.3	50.0
5	49ers	10/10/2004	1-0	SF		vs	ARI		W 31-28	-1	+2 (Y)	36.5	+22.5 (O)	3	28	448	320	40.0	100.0
6	49ers	11/7/2004	0-1	SF		vs	SEA		L 27-42	+7	-8 (N)	39.5	+29.5 (O)	3	19	317	453	27.3	100.0
7	49ers	9/11/2005	1-0	SF		vs	STL		W 28-25	+6	+9 (Y)	46.5	+6.5 (O)	4	12	217	405	14.3
8	49ers	11/20/2005	1-0	SF		vs	SEA		L 25-27	+12.5	+10.5 (Y)	41	+11 (O)	2	17	336	373	38.5
9	49ers	12/4/2005	0-1	SF		vs	ARI		L 10-17	+3	-4 (N)	44.5	-17.5 (U)	1	11	220	404	22.2
10	49ers	9/17/2006	1-0	SF	+145	vs	STL	-165	W 20-13	+3	+10 (Y)	43.5	-10.5 (U)	2	14	360	265	33.3
11	49ers	11/19/2006	1-0	SF	+150	vs	SEA	-170	W 20-14	+3	+9 (Y)	43	-9 (U)	2	18	416	303	23.1
12	49ers	12/24/2006	0-1	SF	-185	vs	ARI	+165	L 20-26	-4	-10 (N)	45	+1 (O)	2	14	223	372	22.2	100.0
13	49ers	9/10/2007	0-0-1	SF	-195	vs	ARI	+170	W 20-17	-3	0 (P)	45	-8 (U)	2	16	194	261	25.0	100.0
14	49ers	9/30/2007	0-1	SF	+110	vs	SEA	-130	L 3-23	+2	-18 (N)	40.5	-14.5 (U)	0	9	184	371	14.3	0.0
15	49ers	11/18/2007	0-1	SF	+155	vs	STL	-175	L 9-13	+3	-1 (N)	39.5	-17.5 (U)	0	13	244	207	21.4
16	49ers	9/7/2008	0-1	SF	+115	vs	ARI	-135	L 13-23	+2.5	-7.5 (N)	41.5	-5.5 (U)	1	13	291	285	37.5
17	49ers	10/26/2008	0-1	SF	-245	vs	SEA	+200	L 13-34	-5	-26 (N)	41	+6 (O)	1	21	388	261	46.7	0.0
18	49ers	11/16/2008	1-0	SF	-300	vs	STL	+250	W 35-16	-7	+12 (Y)	43.5	+7.5 (O)	5	19	334	406	45.5
19	49ers	9/20/2009	1-0	SF	-120	vs	SEA	+100	W 23-10	-1	+12 (Y)	39.5	-6.5 (U)	2	16	379	283	33.3
20	49ers	10/4/2009	1-0	SF	-475	vs	STL	+350	W 35-0	-9.5	+25.5 (Y)	37	-2 (U)	5	13	228	177	30.8
21	49ers	12/14/2009	1-0	SF	+185	vs	ARI	-225	W 24-9	+3	+18 (Y)	44.5	-11.5 (U)	3	18	327	245	50.0
22	49ers	11/14/2010	0-1	SF	-210	vs	STL	+180	W 23-20	-5	-2 (N)	38.5	+4.5 (O)	2	19	421	332	0.0	100.0
23	49ers	12/12/2010	1-0	SF	-220	vs	SEA	+180	W 40-21	-5	+14 (Y)	41.5	+19.5 (O)	4	10	336	361	41.2
24	49ers	1/2/2011	1-0	SF	-250	vs	ARI	+210	W 38-7	-6.5	+24.5 (Y)	39	+6 (O)	5	16	362	279	18.2
25	49ers	9/11/2011	1-0	SF	-250	vs	SEA	+210	W 33-17	-6	+10 (Y)	37.5	+12.5 (O)	3	12	209	219	8.3
	Average		0.9											2.4	18.8	330.9	317.9	33.9	0.0
	Total		28-28-1											139	1,071	18,861	18,118	33.9	56.0

Unlock 2x data

StatMuse has team, game-level data for spread records going back to the 1979 season.

More NFL News

Seahawks pick off Drake Maye 3 times to beat Patriots 13-10 in Super Bowl rematch

Sep 10, 2026

A.J. Brown leaves his Patriots debut with a right ankle injury

Sep 10, 2026

Sam Darnold injures hip on Seahawks' first series of opener and is ruled out for rest of game

Sep 10, 2026

Jeanty returns to practice but Bowers sidelined by knee surgery as Raiders prepare for opener

Sep 10, 2026

Commanders' Jayden Daniels is ready to quiet the critics entering his third NFL season

Sep 10, 2026

Cowboys have a pretty 'cool' way of tracking the heat as they settle for indoor practices

Sep 10, 2026

More 49ers Stats

2026 Division Standings

TEAM	W	PCT
Seahawks	1	1.000
Cardinals	0
Rams	0
49ers	0

Schedule

DATE	MATCHUP			TIME (ET)
Thu 9/10	SF	@	LAR	8:35 PM
Sun 9/20	MIA	@	SF	4:25 PM
Sun 9/27	ARI	@	SF	4:05 PM
Sun 10/4	DEN	@	SF	4:25 PM
Sun 10/11	SF	@	SEA	4:25 PM

NFL 2026 Leaders

Pass Yards Leaders

187

Lock

178

Maye

13

Darnold

Rush Yards Leaders

52

Price

51

Stevenson

47

Maye

Rec Yards Leaders

122

Smith-Njigba

51

Hollins

44

Stevenson

Pass TD Leaders

1

Maye

1

Lock

Rec TD Leaders

1

Smith-Njigba

1

Raridon

QB Rating Leaders

113.3

Lock

54.9

Maye

Sack Leaders

1.0

Jacas

1.0

Thomas

1.0

Hall

NFL 2026 Rankings

PPG Rankings

13.0

10.0

Opp PPG Rankings

10.0

13.0

Total Yards Rankings

285.0

277.0

Rush Yards Rankings

109.0

97.0

Pass Yards Rankings

200.0

178.0

Sack Leaders

3.0

2.0

NFL Fantasy 2026

Fantasy RB Rankings

9.5

Stevenson

5.8

Price

2.9

Holani

Fantasy WR Rankings

18.2

Smith-Njigba

5.1

Hollins

3.5

Kupp

Fantasy TE Rankings

6.2

Raridon

2.6

Henry

1.3

Barner

Fantasy K Rankings

7

Myers

6

Borregales

NFL 2026 Betting

Best Record ATS

0-0-1

Worst Record ATS

0-0-1

NFL 2026 Standings

NFC East	W	L	T	PCT
Cowboys	0	0	0
Commanders	0	0	0
Giants	0	0	0
Eagles	0	0	0
NFC North	W	L	T	PCT
Lions	0	0	0
Packers	0	0	0
Vikings	0	0	0
Bears	0	0	0
NFC South	W	L	T	PCT
Saints	0	0	0
Buccaneers	0	0	0
Panthers	0	0	0
Falcons	0	0	0
NFC West	W	L	T	PCT
Seahawks	1	0	0	1.000
Cardinals	0	0	0
49ers	0	0	0
Rams	0	0	0

AFC East	W	L	T	PCT
Jets	0	0	0
Dolphins	0	0	0
Bills	0	0	0
Patriots	0	1	0	.000
AFC North	W	L	T	PCT
Bengals	0	0	0
Browns	0	0	0
Ravens	0	0	0
Steelers	0	0	0
AFC South	W	L	T	PCT
Texans	0	0	0
Colts	0	0	0
Titans	0	0	0
Jaguars	0	0	0
AFC West	W	L	T	PCT
Raiders	0	0	0
Chiefs	0	0	0
Broncos	0	0	0
Chargers	0	0	0