The San Francisco 49ers were 21-21 against the spread against the NFC West at home between the 2008 and 2021 seasons.

	TEAM	DATE	ATS	TM			OPP		RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	9/7/2008	0-1	SF	+115	vs	ARI	-135	L 13-23	+2.5	-7.5 (N)	41.5	-5.5 (U)	1	13	291	285	37.5
2	49ers	10/26/2008	0-1	SF	-245	vs	SEA	+200	L 13-34	-5	-26 (N)	41	+6 (O)	1	21	388	261	46.7	0.0
3	49ers	11/16/2008	1-0	SF	-300	vs	STL	+250	W 35-16	-7	+12 (Y)	43.5	+7.5 (O)	5	19	334	406	45.5
4	49ers	9/20/2009	1-0	SF	-120	vs	SEA	+100	W 23-10	-1	+12 (Y)	39.5	-6.5 (U)	2	16	379	283	33.3
5	49ers	10/4/2009	1-0	SF	-475	vs	STL	+350	W 35-0	-9.5	+25.5 (Y)	37	-2 (U)	5	13	228	177	30.8
6	49ers	12/14/2009	1-0	SF	+185	vs	ARI	-225	W 24-9	+3	+18 (Y)	44.5	-11.5 (U)	3	18	327	245	50.0
7	49ers	11/14/2010	0-1	SF	-210	vs	STL	+180	W 23-20	-5	-2 (N)	38.5	+4.5 (O)	2	19	421	332	0.0	100.0
8	49ers	12/12/2010	1-0	SF	-220	vs	SEA	+180	W 40-21	-5	+14 (Y)	41.5	+19.5 (O)	4	10	336	361	41.2
9	49ers	1/2/2011	1-0	SF	-250	vs	ARI	+210	W 38-7	-6.5	+24.5 (Y)	39	+6 (O)	5	16	362	279	18.2
10	49ers	9/11/2011	1-0	SF	-250	vs	SEA	+210	W 33-17	-6	+10 (Y)	37.5	+12.5 (O)	3	12	209	219	8.3
11	49ers	11/20/2011	1-0	SF	-600	vs	ARI	+450	W 23-7	-10	+6 (Y)	41	-11 (U)	2	25	431	229	38.1	100.0
12	49ers	12/4/2011	1-0	SF	-800	vs	STL	+600	W 26-0	-14	+12 (Y)	38	-12 (U)	2	18	389	157	28.6
13	49ers	10/18/2012	0-1	SF	-380	vs	SEA	+310	W 13-6	-9	-2 (N)	37.5	-18.5 (U)	1	18	313	251	27.3
14	49ers	11/11/2012	0-1	SF	-800	vs	STL	+600	T 24-24	-13.5	-13.5 (N)	38	+10 (O)	3	25	341	458	18.2	100.0
15	49ers	12/30/2012	0-1	SF	-1600	vs	ARI	+1000	W 27-13	-16.5	-2.5 (N)	38.5	+1.5 (O)	3	20	407	262	28.6	100.0
16	49ers	10/13/2013	1-0	SF	-550	vs	ARI	+400	W 32-20	-10	+2 (Y)	40.5	+11.5 (O)	3	20	387	403	28.6	100.0
17	49ers	12/1/2013	1-0	SF	-370	vs	STL	+310	W 23-13	-7.5	+2.5 (Y)	41	-5 (U)	2	20	338	312	33.3
18	49ers	12/8/2013	0-1	SF	-135	vs	SEA	+115	W 19-17	-2.5	-0.5 (N)	41	-5 (U)	1	19	318	264	38.5
19	49ers	11/2/2014	0-1	SF	-600	vs	STL	+450	L 10-13	-10.5	-13.5 (N)	44	-21 (U)	1	20	263	193	25.0
20	49ers	11/27/2014	0-1	SF	-130	vs	SEA	+110	L 3-19	-1	-17 (N)	40	-18 (U)	0	16	164	379	36.4
21	49ers	12/28/2014	0-1	SF	-300	vs	ARI	+240	W 20-17	-6	-3 (N)	38	-1 (U)	2	18	395	397	41.7
22	49ers	10/22/2015	0-1	SF	+225	vs	SEA	-300	L 3-20	+6	-11 (N)	42	-19 (U)	0	8	142	388	9.1
23	49ers	11/29/2015	1-0	SF	+350	vs	ARI	-430	L 13-19	+8	+2 (Y)	45	-13 (U)	1	17	368	337	0.0	50.0
24	49ers	1/3/2016	1-0	SF	+145	vs	STL	-165	W 19-16	+3	+6 (Y)	38.5	-3.5 (U)	1	21	458	364	44.4	0.0
25	49ers	9/12/2016	1-0	SF	+125	vs	LA	-145	W 28-0	+3	+31 (Y)	42.5	-14.5 (U)	4	28	320	185	47.1	50.0
	Average		1.2											2.5	19.2	338.0	311.4	34.1	2.4
	Total		21-21											103	806	14,195	13,080	34.1	56.1

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More 49ers Stats

Team Leaders

PASS

2,167

Purdy

RUSH

1,202

McCaffrey

REC

924

McCaffrey

Team Rankings

PPG

25.7

10th

OPP PPG

21.8

13th

RUSH YDS/G

106.9

24th

PASS YDS/G

254.0

6th

2025 Division Standings

TEAM	W	L	PCT
Seahawks	14	3	.824
Rams	12	5	.706
49ers	12	5	.706
Cardinals	3	14	.176

Schedule

DATE	MATCHUP			TIME (ET)
Sun 1/11	SF	@	PHI	4:30 PM

Last Game

Seahawks

14 - 3

Final

49ers

12 - 5

Sat 3 Jan 2026

NFL 2025 Leaders

Pass Yards Leaders

4,707

Stafford

4,564

Goff

4,552

Prescott

Rush Yards Leaders

1,621

Cook

1,595

Henry

1,585

Taylor

Rec Yards Leaders

1,793

Smith-Njigba

1,715

Nacua

1,429

Pickens

Pass TD Leaders

46

Stafford

34

Goff

31

Maye

Rush TD Leaders

18

Taylor

16

Henry

14

Allen

Rec TD Leaders

14

Adams

11

McBride

11

St. Brown

QB Rating Leaders

113.5

Maye

109.2

Stafford

105.5

Goff

Sack Leaders

23.0

Garrett

16.5

Burns

15.0

Hunter

NFL 2025 Rankings

PPG Rankings

30.5

28.8

28.4

28.3

27.9

Opp PPG Rankings

17.2

17.4

18.3

18.8

19.1

19.3

Total Yards Rankings

394.6

391.9

379.4

376.3

373.2

369.5

Rush Yards Rankings

159.6

156.6

144.5

134.7

129.1

128.9

Pass Yards Rankings

278.5

276.9

268.6

262.3

256.1

254.0

Sack Leaders

68.0

57.0

53.0

49.0

48.0

NFL Fantasy 2025

Fantasy RB Rankings

316.3

Taylor

314.6

McCaffrey

291.8

Robinson

Fantasy WR Rankings

246

Nacua

240.9

Smith-Njigba

207

St. Brown

Fantasy TE Rankings

189.9

McBride

125.1

Goedert

122.8

Pitts

Fantasy K Rankings

202

Myers

194

Fairbairn

187.6

Aubrey

NFL 2025 Betting

Best Record ATS

12-5

11-6

10-6-1

Worst Record ATS

5-12

5-11-1

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176