The San Francisco 49ers had their most total touchdowns in a game in 2025 on December 28 and on December 22, with 6 touchdowns.
Interpreted as:
49ers most touchdowns in a regular-season game this season| TEAM | TD | DATE | TM | OPP | RESULT | PASS TD | RUSH TD | RET TD | FGM | XPM | XP2 | SFTY | PTS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 6 | 12/28/2025 | vs | W 42-38 | 3 | 3 | 0 | 0 | 6 | 0 | 0 | 42 | ||
| 2 | | 49ers | 6 | 12/22/2025 | @ | W 48-27 | 5 | 0 | 1 | 2 | 6 | 0 | 0 | 48 | ||
| 3 | | 49ers | 5 | 11/16/2025 | @ | W 41-22 | 3 | 2 | 0 | 3 | 2 | 0 | 0 | 41 | ||
| 4 | | 49ers | 4 | 12/14/2025 | vs | W 37-24 | 3 | 1 | 0 | 3 | 4 | 0 | 0 | 37 | ||
| 5 | | 49ers | 4 | 11/9/2025 | vs | L 26-42 | 3 | 1 | 0 | 0 | 2 | 0 | 0 | 26 | ||
| 6 | | 49ers | 4 | 11/2/2025 | @ | W 34-24 | 2 | 2 | 0 | 2 | 4 | 0 | 0 | 34 | ||
| 7 | | 49ers | 3 | 11/30/2025 | @ | W 26-8 | 1 | 2 | 0 | 2 | 2 | 0 | 0 | 26 | ||
| 8 | | 49ers | 3 | 9/14/2025 | @ | W 26-21 | 3 | 0 | 0 | 2 | 2 | 0 | 0 | 26 | ||
| 9 | | 49ers | 2 | 11/24/2025 | vs | W 20-9 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 20 | ||
| 10 | | 49ers | 2 | 10/26/2025 | @ | L 15-26 | 2 | 0 | 0 | 0 | 1 | 1 | 0 | 15 | ||
| 11 | | 49ers | 2 | 10/19/2025 | vs | W 20-10 | 0 | 2 | 0 | 2 | 2 | 0 | 0 | 20 | ||
| 12 | | 49ers | 2 | 10/2/2025 | @ | W 26-23 | 2 | 0 | 0 | 4 | 2 | 0 | 0 | 26 | ||
| 13 | | 49ers | 2 | 9/28/2025 | vs | L 21-26 | 2 | 0 | 0 | 2 | 1 | 1 | 0 | 21 | ||
| 14 | | 49ers | 2 | 9/7/2025 | @ | W 17-13 | 2 | 0 | 0 | 1 | 2 | 0 | 0 | 17 | ||
| 15 | | 49ers | 1 | 10/12/2025 | @ | L 19-30 | 0 | 1 | 0 | 4 | 1 | 0 | 0 | 19 | ||
| 16 | | 49ers | 1 | 9/21/2025 | vs | W 16-15 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 16 |
More NFL News
Geno Smith knows he can write a 'superhero movie' story in his return to the Jets
Bears coach Ben Johnson says he is 'buying Luther Burden stock' going into the season
Steelers RB Rico Dowdle reunites with Mike McCarthy in Pittsburgh after his mom’s spot-on prediction
Chiefs WR Rashee Rice continues serving jail sentence as team begins voluntary offseason workouts
Patrick Mahomes takes a big step forward on his repaired knee, joining Chiefs for voluntary workouts
Jets' Kenyon Sadiq has hernia surgery. Aaron Glenn expects rookie TE to be ready in training camp
More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |