49ers vs. Cardinals (Nov 16, 2025)

Odds

SF

ARI

-1.5

Open

+1.5

Open

-120

ML

+100

ML

o47.5

-110

u47.5

-110

-1.5

-110

+1.5

-110

Passing Matchup

Mac Jones

SF QB #10

Kyler Murray

ARI QB #1

1,252

Pass Yds

962

6

Pass TD

6

3

Int

3

Rushing Matchup

Christian McCaffrey

SF RB #23

Kyler Murray

ARI QB #1

336

Rush Yds

173

3.1

Yds/Rush

6.0

1

Rush TD

1

Receiving Matchup

Christian McCaffrey

SF RB #23

Trey McBride

ARI TE #85

46

Rec

37

444

Rec Yds

347

3

Rec TD

2

SF

Team Stats

ARI

20.8

PPG

21.7

21.3

Opp PPG

21.2

2,242

Total Yds

1,842

1,838

Pass Yds

1,282

493

Rush Yds

679

SF

Injuries

ARI

Upton Stout

DB

questionable (Ankle)

LB

Cody Simon

questionable (Knee)

Alfred Collins

DL

questionable (Knee)

DB

Max Melton

questionable (Hamstring)

Malik Mustapha

DB

questionable (Knee)

P

Blake Gillikin

questionable (Back)

Kalia Davis

DL

questionable (Hand)

QB

Kyler Murray

questionable (Foot)

Mac Jones

QB

questionable (Knee)

LB

Mack Wilson Sr.

questionable (Ankle)

Jauan Jennings

WR

questionable (Ankle)

WR

Zay Jones

questionable (Knee)

Jordan Watkins

WR

out (Calf)

DL

Darius Robinson

out (Pectoral)

Ricky Pearsall

WR

out (Knee)

Brock Purdy

QB

out (Toe)

Yetur Gross-Matos

DL

out (Knee)

Kevin Givens

DL

out (Pectoral)

2025 NFC West

Team	W	L	PCT
49ers	4	2	.667
Seahawks	4	2	.667
Rams	4	2	.667
Cardinals	2	4	.333

SF

Last 5

ARI

Sun, Oct 12

Sun, Oct 12

Thu, Oct 2

Sun, Oct 5

Sun, Sep 28

Thu, Sep 25

Sun, Sep 21

Sun, Sep 21

Sun, Sep 14

Sun, Sep 14

Game Info

November 16, 2025

State Farm Stadium

Glendale, Arizona

Team Leaders

PASS

1,252

Jones

RUSH

336

McCaffrey

REC

444

McCaffrey

	Passing	GP	CMP	ATT	PCT	ATT/G	YDS	AVG	YDS/G	TD	INT	RTG	TD%	INT%	LNG	SCK	SCKY
	Mac Jones M. Jones	4	113	168	67.3	42.0	1,252	7.5	313.0	6	3	93.7	3.6	1.8	56	11	74
	Brock Purdy B. Purdy	2	48	73	65.8	36.5	586	8.0	293.0	4	4	85.8	5.5	5.5	45	2	15

Rushing	GP	ATT	ATT/G	YDS	YPC	YDS/G	TD	LNG	PLY SCM	YDS SCM
Christian McCaffrey C. McCaffrey	6	108	18.0	336	3.1	56.0	1	15	154	780
Brian Robinson Jr. B. Robinson Jr.	6	27	4.5	108	4.0	18.0	0	19	32	119
Mac Jones M. Jones	4	16	4.0	23	1.4	5.8	0	13	16	23
Brock Purdy B. Purdy	2	7	3.5	30	4.3	15.0	0	11	7	30
Skyy Moore S. Moore	6	1	0.2	1	1.0	0.2	0	1	2	11
Kyle Juszczyk K. Juszczyk	6	1	0.2	-1	-1.0	-0.2	0	-1	12	99
Ricky Pearsall R. Pearsall	4	1	0.3	-4	-4.0	-1.0	0	-4	21	323

Receiving	GP	REC	TRG	REC/G	YDS	AVG	YDS/G	TD	LNG	PLY SCM	YDS SCM
Christian McCaffrey C. McCaffrey	6	46	60	7.7	444	9.7	74.0	3	29	154	780
Jake Tonges J. Tonges	6	25	34	4.2	224	9.0	37.3	3	23	25	224
Kendrick Bourne K. Bourne	5	23	33	4.6	371	16.1	74.2	0	56	23	371
Ricky Pearsall R. Pearsall	4	20	29	5.0	327	16.4	81.8	0	45	21	323
Kyle Juszczyk K. Juszczyk	6	11	12	1.8	100	9.1	16.7	1	25	12	99
Jauan Jennings J. Jennings	4	10	22	2.5	136	13.6	34.0	1	42	10	136
Demarcus Robinson D. Robinson	3	6	12	2.0	103	17.2	34.3	0	31	6	103
Luke Farrell L. Farrell	6	6	8	1.0	47	7.8	7.8	1	11	6	47
Brian Robinson Jr. B. Robinson Jr.	6	5	6	0.8	11	2.2	1.8	0	4	32	119
Marquez Valdes-Scantling M. Valdes-Scantling	5	4	8	0.8	40	10.0	8.0	0	19	4	40
George Kittle G. Kittle	1	4	4	4.0	25	6.3	25.0	1	11	4	25
Skyy Moore S. Moore	6	1	2	0.2	10	10.0	1.7	0	10	2	11

Defense	GP	TKL	AST	COMB	TFL	SCK	PDEF	LNG
Fred Warner F. Warner	6	28	23	51	2	0.0	3
Marques Sigle M. Sigle	6	26	17	43	1	0.0	2
Dee Winters D. Winters	6	30	10	40	3	0.0	3
Upton Stout U. Stout	6	13	12	25	2	1.0	2	0
Deommodore Lenoir D. Lenoir	6	17	6	23	3	0.0	1
Renardo Green R. Green	5	11	7	18	0	0.0	5
Luke Gifford L. Gifford	6	5	13	18	0	0.0	0
Jason Pinnock J. Pinnock	6	12	5	17	0	0.0	0
Nick Bosa N. Bosa	3	9	8	17	4	2.0	0
Sam Okuayinonu S. Okuayinonu	6	7	9	16	1	0.0	0
Bryce Huff B. Huff	6	9	5	14	5	3.0	1
Tatum Bethune T. Bethune	6	8	6	14	0	0.0	0
Jordan Elliott J. Elliott	6	4	10	14	1	0.0	0
Mykel Williams M. Williams	6	9	4	13	4	1.0	0
Ji'Ayir Brown J. Brown	6	6	6	12	0	0.0	1
Darrell Luter Jr. D. Luter Jr.	6	4	5	9	1	0.0	0
Kalia Davis K. Davis	6	3	4	7	2	0.0	0
Chase Lucas C. Lucas	6	5	1	6	0	0.0	0
Alfred Collins A. Collins	6	2	4	6	0	0.0	0
Brayden Willis B. Willis	5	3	2	5	0	0.0	0
Siran Neal S. Neal	6	2	3	5	0	0.0	0
C.J. West	5	2	2	4	0	0.0	0
Yetur Gross-Matos Y. Gross-Matos	5	1	3	4	0	0.0	1
Jake Tonges J. Tonges	6	1	2	3	0	0.0	0
Curtis Robinson C. Robinson	6	0	3	3	0	0.0	0
Christian McCaffrey C. McCaffrey	6	1	1	2	0	0.0	0
Colton McKivitz C. McKivitz	6	1	1	2	0	0.0	0
Malik Mustapha M. Mustapha	1	1	1	2	0	0.0	0
Trevis Gipson T. Gipson	2	1	0	1	0	0.0	0
Isaac Guerendo I. Guerendo	6	1	0	1	0	0.0	0
Ricky Pearsall R. Pearsall	4	1	0	1	0	0.0	0
Dominick Puni D. Puni	6	1	0	1	0	0.0	0
Trent Williams T. Williams	6	1	0	1	0	0.0	0
Kyle Juszczyk K. Juszczyk	6	0	1	1	0	0.0	0

Team Leaders

PASS

962

Murray

RUSH

173

Murray

REC

347

McBride

	Passing	GP	CMP	ATT	PCT	ATT/G	YDS	AVG	YDS/G	TD	INT	RTG	TD%	INT%	LNG	SCK	SCKY
	Kyler Murray K. Murray	5	110	161	68.3	32.2	962	6.0	192.4	6	3	88.6	3.7	1.9	45	16	111
	Jacoby Brissett J. Brissett	3	27	45	60.0	15.0	320	7.1	106.7	2	1	87.3	4.4	2.2	30	2	8

Rushing	GP	ATT	ATT/G	YDS	YPC	YDS/G	TD	LNG	PLY SCM	YDS SCM
James Conner J. Conner	3	32	10.7	95	3.0	31.7	1	12	40	133
Kyler Murray K. Murray	5	29	5.8	173	6.0	34.6	1	30	29	173
Trey Benson T. Benson	4	29	7.3	160	5.5	40.0	0	52	42	224
Michael Carter M. Carter	3	28	9.3	86	3.1	28.7	1	11	35	138
Zonovan Knight Z. Knight	4	15	3.8	45	3.0	11.3	2	10	17	78
Emari Demercado E. Demercado	6	8	1.3	90	11.3	15.0	0	71	10	103
Jacoby Brissett J. Brissett	3	4	1.3	21	5.3	7.0	0	12	4	21
Greg Dortch G. Dortch	6	2	0.3	9	4.5	1.5	0	5	15	77

Receiving	GP	REC	TRG	REC/G	YDS	AVG	YDS/G	TD	LNG	PLY SCM	YDS SCM
Trey McBride T. McBride	6	37	53	6.2	347	9.4	57.8	2	31	37	347
Marvin Harrison Jr. M. Harrison Jr.	6	22	34	3.7	338	15.4	56.3	2	45	22	338
Greg Dortch G. Dortch	6	13	14	2.2	68	5.2	11.3	1	15	15	77
Trey Benson T. Benson	4	13	16	3.3	64	4.9	16.0	0	12	42	224
Michael Wilson M. Wilson	6	12	23	2.0	96	8.0	16.0	1	30	12	96
Zay Jones Z. Jones	5	10	15	2.0	116	11.6	23.2	0	24	10	116
Elijah Higgins E. Higgins	6	8	10	1.3	99	12.4	16.5	0	27	8	99
James Conner J. Conner	3	8	9	2.7	38	4.8	12.7	1	18	40	133
Michael Carter M. Carter	3	7	10	2.3	52	7.4	17.3	0	16	35	138
Tip Reiman T. Reiman	4	3	5	0.8	18	6.0	4.5	0	10	3	18
Zonovan Knight Z. Knight	4	2	3	0.5	33	16.5	8.3	0	20	17	78
Emari Demercado E. Demercado	6	2	4	0.3	13	6.5	2.2	1	7	10	103

Defense	GP	TKL	AST	COMB	TFL	SCK	PDEF	INT	YDS	AVG	LNG
Mack Wilson Sr. M. Wilson Sr.	6	28	22	50	3	0.0	6	1	9	9	9
Akeem Davis-Gaither A. Davis-Gaither	6	21	23	44	1	0.0	2	0	0
Jalen Thompson J. Thompson	6	24	19	43	0	0.0	1	0	0
Budda Baker B. Baker	6	19	22	41	1	0.0	2	0	0
Dadrion Taylor-Demerson D. Taylor-Demerson	6	17	10	27	0	0.0	5	2	18	9	18
Max Melton M. Melton	5	12	6	18	0	0.0	4	0	0
Kei'Trel Clark K. Clark	5	9	7	16	1	0.0	2	0	0
Zaven Collins Z. Collins	6	9	7	16	3	0.0	0	0	0
Dante Stills D. Stills	6	5	11	16	0	0.0	1	0	0
Calais Campbell C. Campbell	6	10	5	15	4	3.0	0	0	0
Josh Sweat J. Sweat	6	10	3	13	6	5.0	1	0	0
PJ Mustipher	6	6	6	12	1	0.0	1	0	0
Baron Browning B. Browning	6	4	8	12	3	2.0	1	1	4	4	4
Dalvin Tomlinson D. Tomlinson	6	7	4	11	2	0.0	1	0	0
Garrett Williams G. Williams	2	7	4	11	0	0.0	1	0	0
Will Johnson W. Johnson	4	8	2	10	0	0.0	5	0	0		0
Jordan Burch J. Burch	6	4	6	10	0	0.0	0	0	0
Kitan Crawford K. Crawford	6	5	3	8	0	0.0	1	0	0
Denzel Burke D. Burke	6	5	2	7	0	0.0	3	0	0
Darius Robinson D. Robinson	4	4	1	5	2	1.0	0	0	0
Zachary Carter Z. Carter	2	2	3	5	0	0.0	0	0	0
Cody Simon C. Simon	5	2	3	5	0	0.0	0	0	0
Owen Pappoe O. Pappoe	6	1	4	5	0	0.0	0	0	0
Simi Fehoko S. Fehoko	5	2	2	4	0	0.0	0	0	0
Anthony Goodlow A. Goodlow	3	1	2	3	1	0.0	0	0	0
Darren Hall D. Hall	4	1	2	3	0	0.0	0	0	0
Elijah Higgins E. Higgins	6	0	3	3	0	0.0	0	0	0
Emari Demercado E. Demercado	6	2	0	2	0	0.0	0	0	0
Hjalte Froholdt H. Froholdt	6	2	0	2	0	0.0	0	0	0
Travis Vokolek T. Vokolek	5	2	0	2	0	0.0	0	0	0
Evan Brown E. Brown	5	1	0	1	0	0.0	0	0	0
L.J. Collier	2	1	0	1	0	0.0	0	0	0
Josiah Deguara J. Deguara	1	1	0	1	0	0.0	0	0	0
Zonovan Knight Z. Knight	4	1	0	1	0	0.0	0	0	0
Jonah Williams J. Williams	6	1	0	1	0	0.0	0	0	0
Greg Dortch G. Dortch	6	0	1	1	0	0.0	0	0	0