49ers record against the bills since 2018

The San Francisco 49ers have a record of 0-2 versus the Bills since 2018.

		TEAM	DATE	REC	TM		OPP	RESULT	W%	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1		49ers	12/7/2020	0-1	SF	vs	BUF	L 24-34	.000	3	24	402	449	54.5	0.0
2		49ers	12/1/2024	0-1	SF	@	BUF	L 10-35	.000	1	15	239	372	30.0	100.0
		Average							.000	2.0	19.5	320.5	410.5	42.9	25.0
		Total		0-2					.000	4	39	641	821	42.9	50.0

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More 49ers Stats

PASS

1,404

Jones

Mac Jones

RUSH

465

McCaffrey

Christian McCaffrey

REC

516

McCaffrey

Christian McCaffrey

PPG

20.7

23rd

OPP PPG

19.7

7th

RUSH YDS/G

95.3

25th

PASS YDS/G

284.3

1st

2025 Division Standings

TEAM	W	L	T	PCT
Rams	5	2	0	.714
49ers	5	2	0	.714
Seahawks	5	2	0	.714
Cardinals	2	5	0	.286

DATE	MATCHUP			TIME (ET)
Sun 10/26	SF	@	HOU	1:00 PM
Sun 11/2	SF	@	NYG	1:00 PM
Sun 11/9	LAR	@	SF	4:25 PM
Sun 11/16	SF	@	ARI	4:05 PM
Mon 11/24	CAR	@	SF	8:15 PM

ATL

3 - 3 - 0

10

Final

20

5 - 2 - 0

Sun 19 Oct 2025

NFL 2025 Leaders

Pass Yards Leaders

1,913

Herbert

Justin Herbert

1,881

Prescott

Dak Prescott

1,866

Stafford

Matthew Stafford

Rush Yards Leaders

697

Taylor

Jonathan Taylor

592

Williams

Javonte Williams

551

Dowdle

Rico Dowdle

Rec Yards Leaders

819

Smith-Njigba

Jaxon Smith-Njigba

629

Chase

Ja'Marr Chase

616

Nacua

Puka Nacua

Pass TD Leaders

17

Stafford

Matthew Stafford

16

Prescott

Dak Prescott

15

Goff

Jared Goff

Rush TD Leaders

10

Taylor

Jonathan Taylor

8

Jacobs

Josh Jacobs

6

Gibbs

Jahmyr Gibbs

7

St. Brown

Amon-Ra St. Brown

6

Ferguson

Jake Ferguson

6

Pickens

George Pickens

QB Rating Leaders

130.5

Jackson

Lamar Jackson

116.4

Maye

Drake Maye

116.4

Goff

Jared Goff

9.0

Young

Byron Young

9.0

Burns

Brian Burns

8.0

Bonitto

Nik Bonitto

NFL 2025 Rankings

33.1

31.7

30.7

27.8

27.6

26.6

Opp PPG Rankings

14.7

16.7

17.7

18.1

19.0

19.4

Total Yards Rankings

390.6

380.3

378.3

372.7

370.6

366.6

Rush Yards Rankings

151.0

148.9

140.1

136.3

133.7

131.9

Pass Yards Rankings

284.3

279.6

274.6

266.6

257.1

257.0

34.0

26.0

23.0

23.0

22.0

20.0

NFL Fantasy 2025

Fantasy RB Rankings

156.2

Taylor

Jonathan Taylor

134.1

McCaffrey

Christian McCaffrey

115.4

Robinson

Bijan Robinson

Fantasy WR Rankings

105

Smith-Njigba

Jaxon Smith-Njigba

96.7

Pickens

George Pickens

96.7

St. Brown

Amon-Ra St. Brown

Fantasy TE Rankings

69.4

Ferguson

Jake Ferguson

68.5

Warren

Tyler Warren

66.1

McBride

Trey McBride

Fantasy K Rankings

82

Aubrey

Brandon Aubrey

75

Pineiro

Eddy Pineiro

73

Myers

Jason Myers

NFL 2025 Betting

Best Record ATS

5-2

5-2

5-2

5-2

5-2

5-2

Worst Record ATS

1-5

2-5

2-5

2-5

2-5

2-4

NFL 2025 Division Standings

AFC East	W	L	T	PCT
Patriots	5	2	0	.714
Bills	4	2	0	.667
AFC North	W	L	T	PCT
Steelers	4	2	0	.667
Bengals	3	4	0	.429
AFC South	W	L	T	PCT
Colts	6	1	0	.857
Jaguars	4	3	0	.571
AFC West	W	L	T	PCT
Broncos	5	2	0	.714
Chargers	4	3	0	.571

NFC East	W	L	T	PCT
Eagles	5	2	0	.714
Cowboys	3	3	1	.500
NFC North	W	L	T	PCT
Packers	4	1	1	.750
Lions	5	2	0	.714
NFC South	W	L	T	PCT
Buccaneers	5	2	0	.714
Panthers	4	3	0	.571
NFC West	W	L	T	PCT
49ers	5	2	0	.714
Seahawks	5	2	0	.714

NFL 2025 Scores & Schedule

Scores

DATE	MATCHUP			SCORE
Wed 9/3	DAL	@	PHI	20-24
Thu 9/4	KC	@	LAC	21-27
Sat 9/6	PIT	@	NYJ	34-32
Sat 9/6	TB	@	ATL	23-20
Sat 9/6	LV	@	NE	20-13

Schedule

DATE	MATCHUP			TIME (ET)
Thu 10/23	MIN	@	LAC	8:15 PM
Sun 10/26	NYJ	@	CIN	1:00 PM
Sun 10/26	BUF	@	CAR	1:00 PM
Sun 10/26	SF	@	HOU	1:00 PM
Sun 10/26	NYG	@	PHI	1:00 PM