The San Francisco 49ers are 6-4 on Mondays in the regular-season and playoffs on the road since 2006.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 11/12/2007 | 0-1 | @ | L 0-24 | .000 | 0 | 6 | 173 | 380 | 8.3 | 0.0 | ||
| 2 | | 49ers | 11/10/2008 | 0-1 | @ | L 24-29 | .000 | 3 | 19 | 336 | 374 | 50.0 | |||
| 3 | | 49ers | 11/29/2010 | 1-0 | @ | W 27-6 | 1.000 | 3 | 26 | 386 | 203 | 53.8 | |||
| 4 | | 49ers | 10/29/2012 | 1-0 | @ | W 24-3 | 1.000 | 3 | 15 | 317 | 265 | 50.0 | |||
| 5 | | 49ers | 11/25/2013 | 1-0 | @ | W 27-6 | 1.000 | 3 | 15 | 304 | 190 | 28.6 | 50.0 | ||
| 6 | | 49ers | 10/13/2014 | 1-0 | @ | W 31-17 | 1.000 | 4 | 17 | 432 | 309 | 42.9 | 0.0 | ||
| 7 | | 49ers | 10/15/2018 | 0-1 | @ | L 30-33 | .000 | 3 | 18 | 401 | 521 | 22.2 | |||
| 8 | | 49ers | 11/21/2022 | 1-0 | @ | W 38-10 | 1.000 | 5 | 21 | 387 | 314 | 54.5 | |||
| 9 | | 49ers | 10/23/2023 | 0-1 | @ | L 17-22 | .000 | 2 | 19 | 325 | 452 | 55.6 | 100.0 | ||
| 10 | | 49ers | 12/22/2025 | 1-0 | @ | W 48-27 | 1.000 | 6 | 28 | 440 | 312 | 63.6 | 100.0 | ||
| Average | .600 | 3.2 | 18.4 | 350.1 | 332.0 | 43.1 | 6.7 | ||||||||
| Total | 6-4 | .600 | 32 | 184 | 3,501 | 3,320 | 43.1 | 33.3 |
WAS
STLMore 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
