
The San Francisco 49ers have a record of 65-45-1 against the NFC in the regular-season and playoffs at home since 2009.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 49ers | 9/20/2009 | 1-0 | vs | W 23-10 | 1.000 | 2 | 16 | 379 | 283 | 33.3 | ||||
| 2 | 49ers | 10/4/2009 | 1-0 | vs | W 35-0 | 1.000 | 5 | 13 | 228 | 177 | 30.8 | ||||
| 3 | 49ers | 10/11/2009 | 0-1 | vs | L 10-45 | .000 | 1 | 13 | 279 | 477 | 28.6 | 50.0 | |||
| 4 | 49ers | 11/12/2009 | 1-0 | vs | W 10-6 | 1.000 | 1 | 12 | 216 | 350 | 42.9 | 0.0 | |||
| 5 | 49ers | 12/14/2009 | 1-0 | vs | W 24-9 | 1.000 | 3 | 18 | 327 | 245 | 50.0 | ||||
| 6 | 49ers | 12/27/2009 | 1-0 | vs | W 20-6 | 1.000 | 2 | 13 | 310 | 289 | 29.4 | 50.0 | |||
| 7 | 49ers | 9/20/2010 | 0-1 | vs | L 22-25 | .000 | 3 | 24 | 417 | 287 | 55.6 | ||||
| 8 | 49ers | 10/10/2010 | 0-1 | vs | L 24-27 | .000 | 3 | 21 | 364 | 352 | 61.5 | ||||
| 9 | 49ers | 11/14/2010 | 1-0 | vs | W 23-20 | 1.000 | 2 | 19 | 421 | 332 | 0.0 | 100.0 | |||
| 10 | 49ers | 11/21/2010 | 0-1 | vs | L 0-21 | .000 | 0 | 11 | 189 | 299 | 25.0 | 0.0 | |||
| 11 | 49ers | 12/12/2010 | 1-0 | vs | W 40-21 | 1.000 | 4 | 10 | 336 | 361 | 41.2 | ||||
| 12 | 49ers | 1/2/2011 | 1-0 | vs | W 38-7 | 1.000 | 5 | 16 | 362 | 279 | 18.2 | ||||
| 13 | 49ers | 9/11/2011 | 1-0 | vs | W 33-17 | 1.000 | 3 | 12 | 209 | 219 | 8.3 | ||||
| 14 | 49ers | 9/18/2011 | 0-1 | vs | L 24-27 | .000 | 3 | 14 | 206 | 472 | 50.0 | ||||
| 15 | 49ers | 10/9/2011 | 1-0 | vs | W 48-3 | 1.000 | 6 | 28 | 418 | 272 | 28.6 | 100.0 | |||
| 16 | 49ers | 11/13/2011 | 1-0 | vs | W 27-20 | 1.000 | 2 | 16 | 305 | 395 | 27.3 | ||||
| 17 | 49ers | 11/20/2011 | 1-0 | vs | W 23-7 | 1.000 | 2 | 25 | 431 | 229 | 38.1 | 100.0 | |||
| 18 | 49ers | 12/4/2011 | 1-0 | vs | W 26-0 | 1.000 | 2 | 18 | 389 | 157 | 28.6 | ||||
| 19 | 49ers | 1/14/2012 | 1-0 | vs | W 36-32 | 1.000 | 4 | 17 | 407 | 472 | 26.7 | ||||
| 20 | 49ers | 1/22/2012 | 0-1 | vs | L 17-20 | .000 | 2 | 15 | 328 | 352 | 7.7 | ||||
| 21 | 49ers | 9/16/2012 | 1-0 | vs | W 27-19 | 1.000 | 3 | 24 | 349 | 296 | 36.4 | ||||
| 22 | 49ers | 10/14/2012 | 0-1 | vs | L 3-26 | .000 | 0 | 14 | 314 | 342 | 28.6 | 0.0 | |||
| 23 | 49ers | 10/18/2012 | 1-0 | vs | W 13-6 | 1.000 | 1 | 18 | 313 | 251 | 27.3 | ||||
| 24 | 49ers | 11/11/2012 | 0-0-1 | vs | T 24-24 | .500 | 3 | 25 | 341 | 458 | 18.2 | 100.0 | |||
| 25 | 49ers | 11/19/2012 | 1-0 | vs | W 32-7 | 1.000 | 3 | 18 | 353 | 143 | 33.3 | ||||
| Average | .590 | 2.7 | 19.7 | 348.7 | 315.9 | 39.5 | 0.7 | ||||||||
| Total | 65-45-1 | .590 | 297 | 2,189 | 38,701 | 35,060 | 39.5 | 47.2 | |||||||
More 49ers Stats
Team Leaders
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
14 | 3 | 0 | .824 | |
12 | 5 | 0 | .706 | |
7 | 10 | 0 | .412 | |
3 | 14 | 0 | .176 | |
| AFC North | W | L | T | PCT |
10 | 7 | 0 | .588 | |
8 | 9 | 0 | .471 | |
6 | 11 | 0 | .353 | |
5 | 12 | 0 | .294 | |
| AFC South | W | L | T | PCT |
13 | 4 | 0 | .765 | |
12 | 5 | 0 | .706 | |
8 | 9 | 0 | .471 | |
3 | 14 | 0 | .176 | |
| AFC West | W | L | T | PCT |
14 | 3 | 0 | .824 | |
11 | 6 | 0 | .647 | |
6 | 11 | 0 | .353 | |
3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
11 | 6 | 0 | .647 | |
7 | 9 | 1 | .441 | |
5 | 12 | 0 | .294 | |
4 | 13 | 0 | .235 | |
| NFC North | W | L | T | PCT |
11 | 6 | 0 | .647 | |
9 | 7 | 1 | .559 | |
9 | 8 | 0 | .529 | |
9 | 8 | 0 | .529 | |
| NFC South | W | L | T | PCT |
8 | 9 | 0 | .471 | |
8 | 9 | 0 | .471 | |
8 | 9 | 0 | .471 | |
6 | 11 | 0 | .353 | |
| NFC West | W | L | T | PCT |
14 | 3 | 0 | .824 | |
12 | 5 | 0 | .706 | |
12 | 5 | 0 | .706 | |
3 | 14 | 0 | .176 |








