The San Francisco 49ers have a 29-11 record as favorites against the Cardinals all-time.

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Regular season

	TEAM	DATE	REC	TM		OPP	RESULT	W%	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	9/14/1980	1-0	SF	vs	STL	W 24-21	1.000	3	19	392	342
2	49ers	11/21/1982	1-0	SF	@	STL	W 31-20	1.000	4	22	448	254
3	49ers	9/18/1983	1-0	SF	@	STL	W 42-27	1.000	6	24	527	385
4	49ers	11/9/1986	1-0	SF	vs	STL	W 43-17	1.000	5	23	460	364
5	49ers	11/6/1988	0-1	SF	@	PHX	L 23-24	.000	2	22	357	355
6	49ers	11/17/1991	1-0	SF	vs	PHX	W 14-10	1.000	2	22	257	176	60.0
7	49ers	11/1/1992	0-1	SF	@	PHX	L 14-24	.000	2	19	330	342	14.3	0.0
8	49ers	10/24/1993	1-0	SF	vs	PHX	W 28-14	1.000	4	26	428	429	50.0
9	49ers	9/27/1999	1-0	SF	@	ARI	W 24-10	1.000	3	18	322	250	43.8
10	49ers	10/1/2000	1-0	SF	vs	ARI	W 27-20	1.000	3	18	345	365	43.8
11	49ers	10/27/2002	1-0	SF	vs	ARI	W 38-28	1.000	5	18	357	420	50.0	100.0
12	49ers	12/21/2002	1-0	SF	@	ARI	W 17-14	1.000	2	21	358	184	55.0	50.0
13	49ers	10/26/2003	0-1	SF	@	ARI	L 13-16	.000	2	15	255	314	50.0
14	49ers	12/7/2003	1-0	SF	vs	ARI	W 50-14	1.000	7	30	496	210	50.0	0.0
15	49ers	10/10/2004	1-0	SF	vs	ARI	W 31-28	1.000	3	28	448	320	40.0	100.0
16	49ers	12/24/2006	0-1	SF	vs	ARI	L 20-26	.000	2	14	223	372	22.2	100.0
17	49ers	9/10/2007	1-0	SF	vs	ARI	W 20-17	1.000	2	16	194	261	25.0	100.0
18	49ers	11/29/2010	1-0	SF	@	ARI	W 27-6	1.000	3	26	386	203	53.8
19	49ers	1/2/2011	1-0	SF	vs	ARI	W 38-7	1.000	5	16	362	279	18.2
20	49ers	11/20/2011	1-0	SF	vs	ARI	W 23-7	1.000	2	25	431	229	38.1	100.0
21	49ers	12/11/2011	0-1	SF	@	ARI	L 19-21	.000	1	12	233	325	17.6	50.0
22	49ers	10/29/2012	1-0	SF	@	ARI	W 24-3	1.000	3	15	317	265	50.0
23	49ers	12/30/2012	1-0	SF	vs	ARI	W 27-13	1.000	3	20	407	262	28.6	100.0
24	49ers	10/13/2013	1-0	SF	vs	ARI	W 32-20	1.000	3	20	387	403	28.6	100.0
25	49ers	9/21/2014	0-1	SF	@	ARI	L 14-23	.000	2	20	318	338	50.0	100.0
	Average							.725	3.3	21.2	366.5	322.2
	Total		29-11					.725	132	847	14,659	12,887

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More 49ers Stats

Team Leaders

PASS

1,196

Purdy

RUSH

286

McCaffrey

REC

326

Evans

Team Rankings

PPG

30.8

3rd

OPP PPG

18.6

3rd

RUSH YDS/G

128.6

8th

PASS YDS/G

239.2

15th

2026 Division Standings

TEAM	W	L	PCT
49ers	5	0	1.000
Seahawks	3	2	.600
Rams	2	3	.400
Cardinals	1	4	.200

Schedule

DATE	MATCHUP			TIME (ET)
Mon 10/19	WAS	@	SF	8:15 PM
Sun 10/25	SF	@	ATL	1:00 PM
Sun 11/8	LV	@	SF	4:05 PM
Sun 11/15	SF	@	DAL	4:25 PM
Sun 11/22	MIN	@	SF	8:20 PM

Last Game

49ers

5 - 0

Final

Seahawks

3 - 2

Sun 11 Oct 2026

NFL 2026 Leaders

Pass Yards Leaders

1,572

Stafford

1,485

Goff

1,408

Love

Rush Yards Leaders

580

Robinson

537

Walker

532

Cook

Rec Yards Leaders

583

Smith-Njigba

537

Olave

507

Lamb

Pass TD Leaders

13

Purdy

12

Goff

12

Cousins

Rush TD Leaders

8

Allen

7

Gibbs

7

Henry

Rec TD Leaders

7

Smith-Njigba

6

Watson

5

St. Brown

QB Rating Leaders

119.6

Jackson

119.3

Purdy

111.3

Goff

Sack Leaders

7.5

Anderson

6.0

Rousseau

5.5

Turner

NFL 2026 Rankings

PPG Rankings

32.8

30.8

30.3

29.5

29.2

Opp PPG Rankings

12.8

14.0

18.6

18.8

19.2

Total Yards Rankings

424.4

412.0

405.8

396.2

394.2

393.8

Rush Yards Rankings

173.2

166.8

164.4

162.3

158.0

139.6

Pass Yards Rankings

317.0

297.0

281.6

280.4

276.2

Sack Leaders

20.0

18.0

17.0

16.0

NFL Fantasy 2026

Fantasy RB Rankings

126.7

Gibbs

103.8

Henry

103.2

Robinson

Fantasy WR Rankings

102.5

Smith-Njigba

83.4

Watson

76.1

Lamb

Fantasy TE Rankings

52.4

Likely

50.8

Kittle

49.6

LaPorta

Fantasy K Rankings

75

Shrader

68

Reichard

54

Loop

NFL 2026 Betting

Best Record ATS

4-1

3-1-1

Worst Record ATS

0-4-1

1-4

1-3-1

2-3

NFL 2026 Standings

NFC East	W	L	T	PCT
Giants	3	1	1	.700
Eagles	2	3	0	.400
Cowboys	2	3	0	.400
Commanders	1	3	1	.300
NFC North	W	L	T	PCT
Vikings	5	0	0	1.000
Packers	3	2	0	.600
Lions	3	2	0	.600
Bears	3	2	0	.600
NFC South	W	L	T	PCT
Panthers	2	2	0	.500
Falcons	2	3	0	.400
Buccaneers	1	4	0	.200
Saints	1	4	0	.200
NFC West	W	L	T	PCT
49ers	5	0	0	1.000
Seahawks	3	2	0	.600
Rams	2	3	0	.400
Cardinals	1	4	0	.200

AFC East	W	L	T	PCT
Bills	4	1	0	.800
Patriots	3	2	0	.600
Jets	2	3	0	.400
Dolphins	0	5	0	.000
AFC North	W	L	T	PCT
Ravens	4	1	0	.800
Browns	3	2	0	.600
Steelers	3	2	0	.600
Bengals	3	2	0	.600
AFC South	W	L	T	PCT
Jaguars	4	1	0	.800
Colts	2	3	0	.400
Texans	1	4	0	.200
Titans	0	5	0	.000
AFC West	W	L	T	PCT
Chiefs	4	0	0	1.000
Broncos	3	2	0	.600
Raiders	3	2	0	.600
Chargers	0	5	0	.000