The San Francisco 49ers had a 10-10 record versus the St. Louis Rams between the 2000 and 2009 seasons.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 9/17/2000 | 0-1 | @ | L 24-41 | .000 | 3 | 16 | 401 | 529 | 20.0 | 100.0 | ||
| 2 | | 49ers | 10/29/2000 | 0-1 | vs | L 24-34 | .000 | 3 | 15 | 325 | 447 | 37.5 | 0.0 | ||
| 3 | | 49ers | 9/23/2001 | 0-1 | vs | L 26-30 | .000 | 3 | 14 | 232 | 425 | 31.3 | 100.0 | ||
| 4 | | 49ers | 12/9/2001 | 0-1 | @ | L 14-27 | .000 | 2 | 16 | 220 | 385 | 35.7 | 50.0 | ||
| 5 | | 49ers | 10/6/2002 | 1-0 | vs | W 37-13 | 1.000 | 4 | 21 | 386 | 313 | 44.4 | |||
| 6 | | 49ers | 12/30/2002 | 0-1 | @ | L 20-31 | .000 | 2 | 19 | 329 | 263 | 42.9 | |||
| 7 | | 49ers | 9/14/2003 | 0-1 | @ | L 24-27 | .000 | 3 | 20 | 390 | 278 | 28.6 | 100.0 | ||
| 8 | | 49ers | 11/2/2003 | 1-0 | vs | W 30-10 | 1.000 | 4 | 24 | 389 | 340 | 69.2 | |||
| 9 | | 49ers | 10/3/2004 | 0-1 | vs | L 14-24 | .000 | 2 | 26 | 332 | 360 | 58.3 | 50.0 | ||
| 10 | | 49ers | 12/5/2004 | 0-1 | @ | L 6-16 | .000 | 0 | 9 | 160 | 350 | 15.4 | 100.0 | ||
| 11 | | 49ers | 9/11/2005 | 1-0 | vs | W 28-25 | 1.000 | 4 | 12 | 217 | 405 | 14.3 | |||
| 12 | | 49ers | 12/24/2005 | 1-0 | @ | W 24-20 | 1.000 | 3 | 15 | 321 | 389 | 25.0 | |||
| 13 | | 49ers | 9/17/2006 | 1-0 | vs | W 20-13 | 1.000 | 2 | 14 | 360 | 265 | 33.3 | |||
| 14 | | 49ers | 11/26/2006 | 0-1 | @ | L 17-20 | .000 | 2 | 20 | 319 | 349 | 45.5 | |||
| 15 | | 49ers | 9/16/2007 | 1-0 | @ | W 17-16 | 1.000 | 2 | 8 | 186 | 392 | 23.1 | 100.0 | ||
| 16 | | 49ers | 11/18/2007 | 0-1 | vs | L 9-13 | .000 | 0 | 13 | 244 | 207 | 21.4 | |||
| 17 | | 49ers | 11/16/2008 | 1-0 | vs | W 35-16 | 1.000 | 5 | 19 | 334 | 406 | 45.5 | |||
| 18 | | 49ers | 12/21/2008 | 1-0 | @ | W 17-16 | 1.000 | 2 | 15 | 273 | 343 | 36.4 | 100.0 | ||
| 19 | | 49ers | 10/4/2009 | 1-0 | vs | W 35-0 | 1.000 | 5 | 13 | 228 | 177 | 30.8 | |||
| 20 | | 49ers | 1/3/2010 | 1-0 | @ | W 28-6 | 1.000 | 4 | 16 | 329 | 109 | 26.7 | 0.0 | ||
| Average | .500 | 2.8 | 16.3 | 298.8 | 336.6 | 34.6 | 7.3 | ||||||||
| Total | 10-10 | .500 | 55 | 325 | 5,975 | 6,732 | 34.6 | 73.3 |
STLMore 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
