The San Francisco 49ers have a record of 6-4 against the Rams between January 11, 2021 and January 11, 2026.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 11/15/2021 | 1-0 | vs | W 31-10 | 1.000 | 4 | 20 | 335 | 278 | 57.1 | 50.0 | ||
| 2 | | 49ers | 1/9/2022 | 1-0 | @ | W 27-24 | 1.000 | 3 | 23 | 449 | 265 | 64.3 | |||
| 3 | | 49ers | 10/3/2022 | 1-0 | vs | W 24-9 | 1.000 | 3 | 13 | 327 | 257 | 41.7 | 0.0 | ||
| 4 | | 49ers | 10/30/2022 | 1-0 | @ | W 31-14 | 1.000 | 4 | 22 | 368 | 223 | 55.6 | |||
| 5 | | 49ers | 9/17/2023 | 1-0 | @ | W 30-23 | 1.000 | 3 | 21 | 365 | 386 | 22.2 | |||
| 6 | | 49ers | 1/7/2024 | 0-1 | vs | L 20-21 | .000 | 3 | 20 | 300 | 258 | 50.0 | 100.0 | ||
| 7 | | 49ers | 9/22/2024 | 0-1 | @ | L 24-27 | .000 | 3 | 25 | 425 | 296 | 54.5 | 100.0 | ||
| 8 | | 49ers | 12/12/2024 | 0-1 | vs | L 6-12 | .000 | 0 | 11 | 191 | 302 | 25.0 | |||
| 9 | | 49ers | 10/2/2025 | 1-0 | @ | W 26-23 | 1.000 | 2 | 27 | 407 | 456 | 38.9 | 100.0 | ||
| 10 | | 49ers | 11/9/2025 | 0-1 | vs | L 26-42 | .000 | 4 | 24 | 393 | 401 | 37.5 | 33.3 | ||
| Average | .600 | 2.9 | 20.6 | 356.0 | 312.2 | 45.3 | 10.6 | ||||||||
| Total | 6-4 | .600 | 29 | 206 | 3,560 | 3,122 | 45.3 | 63.6 |
More 49ers Stats
Team Leaders 
PASS
2,167
Purdy
RUSH
1,202
McCaffrey
REC
924
McCaffrey
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
