49ers vs. Cardinals (Nov 16, 2025)

Odds

SF

ARI

-1.5

Open

+1.5

Open

-120

ML

+100

ML

o47.5

-110

u47.5

-110

-1.5

-110

+1.5

-110

Passing Matchup

Mac Jones

SF QB #10

Kyler Murray

ARI QB #1

1,597

Pass Yds

962

8

Pass TD

6

5

Int

3

Rushing Matchup

Christian McCaffrey

SF RB #23

Kyler Murray

ARI QB #1

490

Rush Yds

173

3.5

Yds/Rush

6.0

3

Rush TD

1

Receiving Matchup

Christian McCaffrey

SF RB #23

Trey McBride

ARI TE #85

56

Rec

47

559

Rec Yds

421

3

Rec TD

4

SF

Team Stats

ARI

20.0

PPG

21.9

20.5

Opp PPG

22.0

2,789

Total Yds

2,172

2,183

Pass Yds

1,561

715

Rush Yds

773

SF

Injuries

ARI

Deommodore Lenoir

DB

questionable (Quadricep)

DB

Kitan Crawford

questionable (Ankle)

Luke Gifford

LB

questionable (Hamstring)

DL

Darius Robinson

questionable (Pectoral)

Ricky Pearsall

WR

out (Knee)

QB

Kyler Murray

questionable (Foot)

Brock Purdy

QB

out (Toe)

OL

Will Hernandez

questionable (Knee)

Spencer Burford

OL

out (Knee)

WR

Zay Jones

questionable (Knee)

Bryce Huff

DL

out (Hamstring)

DL

Walter Nolen III

out (Calf)

Yetur Gross-Matos

DL

out (Knee)

RB

Emari Demercado

out (Ankle)

Jake Brendel

OL

out (Hamstring)

2025 NFC West

Team	W	L	PCT
Seahawks	5	2	.714
Rams	5	2	.714
49ers	5	3	.625
Cardinals	2	5	.286

SF

Last 5

ARI

Sun, Oct 26

Sun, Oct 19

Sun, Oct 19

Sun, Oct 12

Sun, Oct 12

Sun, Oct 5

Thu, Oct 2

Thu, Sep 25

Sun, Sep 28

Sun, Sep 21

Game Info

November 16, 2025

State Farm Stadium

Glendale, Arizona

Team Leaders

PASS

1,597

Jones

RUSH

490

McCaffrey

REC

559

McCaffrey

	Passing	GP	CMP	ATT	PCT	ATT/G	YDS	AVG	YDS/G	TD	INT	RTG	TD%	INT%	LNG	SCK	SCKY
	Mac Jones M. Jones	6	149	226	65.9	37.7	1,597	7.1	266.2	8	5	89.0	3.5	2.2	56	14	94
	Brock Purdy B. Purdy	2	48	73	65.8	36.5	586	8.0	293.0	4	4	85.8	5.5	5.5	45	2	15

Rushing	GP	ATT	ATT/G	YDS	YPC	YDS/G	TD	LNG	PLY SCM	YDS SCM
Christian McCaffrey C. McCaffrey	8	140	17.5	490	3.5	61.3	3	15	196	1,049
Brian Robinson Jr. B. Robinson Jr.	8	36	4.5	144	4.0	18.0	0	19	41	155
Mac Jones M. Jones	6	23	3.8	57	2.5	9.5	0	13	23	57
Brock Purdy B. Purdy	2	7	3.5	30	4.3	15.0	0	11	7	30
Skyy Moore S. Moore	8	1	0.1	1	1.0	0.1	0	1	3	26
Kyle Juszczyk K. Juszczyk	8	2	0.3	-3	-1.5	-0.4	0	-1	15	111
Ricky Pearsall R. Pearsall	4	1	0.3	-4	-4.0	-1.0	0	-4	21	323

Receiving	GP	REC	TRG	REC/G	YDS	AVG	YDS/G	TD	LNG	PLY SCM	YDS SCM
Christian McCaffrey C. McCaffrey	8	56	74	7.0	559	10.0	69.9	3	29	196	1,049
Kendrick Bourne K. Bourne	7	28	39	4.0	429	15.3	61.3	0	56	28	429
Ricky Pearsall R. Pearsall	4	20	29	5.0	327	16.4	81.8	0	45	21	323
Jake Tonges J. Tonges	8	26	35	3.3	226	8.7	28.3	4	23	26	226
Jauan Jennings J. Jennings	6	18	36	3.0	212	11.8	35.3	1	42	18	212
Kyle Juszczyk K. Juszczyk	8	13	15	1.6	114	8.8	14.3	1	25	15	111
Demarcus Robinson D. Robinson	5	8	16	1.6	108	13.5	21.6	0	31	8	108
George Kittle G. Kittle	3	8	11	2.7	68	8.5	22.7	2	17	8	68
Luke Farrell L. Farrell	8	7	9	0.9	58	8.3	7.3	1	11	7	58
Marquez Valdes-Scantling M. Valdes-Scantling	5	4	8	0.8	40	10.0	8.0	0	19	4	40
Skyy Moore S. Moore	8	2	4	0.3	25	12.5	3.1	0	15	3	26
Brian Robinson Jr. B. Robinson Jr.	8	5	6	0.6	11	2.2	1.4	0	4	41	155
Jordan Watkins J. Watkins	1	1	2	1.0	7	7.0	7.0	0	7	1	7
Connor Colby C. Colby	8	1	1	0.1	-1	-1.0	-0.1	0	-1	1	-1

Defense	GP	TKL	AST	COMB	TFL	SCK	PDEF	INT	YDS	AVG	LNG
Dee Winters D. Winters	8	40	14	54	4	0.0	3	0	0
Fred Warner F. Warner	6	28	23	51	2	0.0	3	0	0
Marques Sigle M. Sigle	8	27	19	46	1	0.0	2	0	0
Tatum Bethune T. Bethune	8	16	22	38	1	0.0	0	0	0
Upton Stout U. Stout	7	19	15	34	2	1.0	2	0	0		0
Deommodore Lenoir D. Lenoir	8	21	8	29	3	0.0	3	1	26	26	26
Renardo Green R. Green	7	16	11	27	0	0.0	5	0	0
Ji'Ayir Brown J. Brown	8	15	7	22	1	0.0	1	0	0
Sam Okuayinonu S. Okuayinonu	8	10	12	22	2	1.0	0	0	0
Jason Pinnock J. Pinnock	8	14	6	20	0	0.0	0	0	0
Malik Mustapha M. Mustapha	3	10	10	20	1	0.0	0	0	0
Bryce Huff B. Huff	7	11	8	19	6	4.0	1	0	0
Mykel Williams M. Williams	8	11	8	19	4	1.0	0	0	0
Luke Gifford L. Gifford	8	5	14	19	0	0.0	0	0	0
Nick Bosa N. Bosa	3	9	8	17	4	2.0	0	0	0
Jordan Elliott J. Elliott	8	4	12	16	1	0.0	0	0	0
Darrell Luter Jr. D. Luter Jr.	8	8	6	14	1	0.0	0	0	0
Curtis Robinson C. Robinson	8	4	7	11	1	0.0	0	0	0
Kalia Davis K. Davis	8	5	5	10	2	0.0	1	0	0
Siran Neal S. Neal	8	3	6	9	0	0.0	0	0	0
Alfred Collins A. Collins	8	2	6	8	0	0.0	0	0	0
Chase Lucas C. Lucas	8	5	1	6	0	0.0	1	0	0
Brayden Willis B. Willis	5	3	2	5	0	0.0	0	0	0
Robert Beal Jr. R. Beal Jr.	2	2	3	5	0	0.0	0	0	0
Jake Tonges J. Tonges	8	2	2	4	0	0.0	0	0	0
C.J. West	6	2	2	4	0	0.0	0	0	0
Yetur Gross-Matos Y. Gross-Matos	5	1	3	4	0	0.0	1	0	0
Malik Turner M. Turner	3	3	0	3	0	0.0	0	0	0
Isaac Guerendo I. Guerendo	8	2	0	2	0	0.0	0	0	0
Trevis Gipson T. Gipson	4	1	1	2	0	0.0	0	0	0
Christian McCaffrey C. McCaffrey	8	1	1	2	0	0.0	0	0	0
Colton McKivitz C. McKivitz	8	1	1	2	0	0.0	0	0	0
Luke Farrell L. Farrell	8	0	2	2	0	0.0	0	0	0
Jauan Jennings J. Jennings	6	1	0	1	0	0.0	0	0	0
Mac Jones M. Jones	6	1	0	1	0	0.0	0	0	0
Ricky Pearsall R. Pearsall	4	1	0	1	0	0.0	0	0	0
Dominick Puni D. Puni	8	1	0	1	0	0.0	0	0	0
Trent Williams T. Williams	8	1	0	1	0	0.0	0	0	0
Kyle Juszczyk K. Juszczyk	8	0	1	1	0	0.0	0	0	0
Nick Martin N. Martin	2	0	1	1	0	0.0	0	0	0

Team Leaders

PASS

962

Murray

RUSH

173

Murray

REC

421

McBride

	Passing	GP	CMP	ATT	PCT	ATT/G	YDS	AVG	YDS/G	TD	INT	RTG	TD%	INT%	LNG	SCK	SCKY
	Kyler Murray K. Murray	5	110	161	68.3	32.2	962	6.0	192.4	6	3	88.6	3.7	1.9	45	16	111
	Jacoby Brissett J. Brissett	4	52	81	64.2	20.3	599	7.4	149.8	4	1	97.7	4.9	1.2	43	8	51

Rushing	GP	ATT	ATT/G	YDS	YPC	YDS/G	TD	LNG	PLY SCM	YDS SCM
Kyler Murray K. Murray	5	29	5.8	173	6.0	34.6	1	30	29	173
Trey Benson T. Benson	4	29	7.3	160	5.5	40.0	0	52	42	224
Bam Knight B. Knight	5	29	5.8	102	3.5	20.4	2	10	34	142
Michael Carter M. Carter	4	35	8.8	97	2.8	24.3	1	11	44	174
James Conner J. Conner	3	32	10.7	95	3.0	31.7	1	12	40	133
Emari Demercado E. Demercado	6	8	1.3	90	11.3	15.0	0	71	10	103
Jacoby Brissett J. Brissett	4	10	2.5	47	4.7	11.8	0	12	10	47
Greg Dortch G. Dortch	7	2	0.3	9	4.5	1.3	0	5	17	82
D'Ernest Johnson D. Johnson	1	1	1.0	0	0.0	0.0	0	0	1	0

Receiving	GP	REC	TRG	REC/G	YDS	AVG	YDS/G	TD	LNG	PLY SCM	YDS SCM
Trey McBride T. McBride	7	47	66	6.7	421	9.0	60.1	4	31	47	421
Marvin Harrison Jr. M. Harrison Jr.	7	24	40	3.4	396	16.5	56.6	2	45	24	396
Zay Jones Z. Jones	6	12	17	2.0	183	15.3	30.5	0	43	12	183
Michael Wilson M. Wilson	7	15	27	2.1	136	9.1	19.4	1	30	15	136
Elijah Higgins E. Higgins	7	9	11	1.3	102	11.3	14.6	0	27	9	102
Michael Carter M. Carter	4	9	12	2.3	77	8.6	19.3	0	16	44	174
Greg Dortch G. Dortch	7	15	16	2.1	73	4.9	10.4	1	15	17	82
Trey Benson T. Benson	4	13	16	3.3	64	4.9	16.0	0	12	42	224
Bam Knight B. Knight	5	5	7	1.0	40	8.0	8.0	0	20	34	142
James Conner J. Conner	3	8	9	2.7	38	4.8	12.7	1	18	40	133
Tip Reiman T. Reiman	4	3	5	0.8	18	6.0	4.5	0	10	3	18
Emari Demercado E. Demercado	6	2	4	0.3	13	6.5	2.2	1	7	10	103

Defense	GP	TKL	AST	COMB	TFL	SCK	PDEF	INT	YDS	AVG	LNG
Mack Wilson Sr. M. Wilson Sr.	7	31	22	53	3	0.0	6	1	9	9	9
Akeem Davis-Gaither A. Davis-Gaither	7	25	26	51	1	0.0	3	0	0
Budda Baker B. Baker	7	23	26	49	1	0.0	2	0	0
Jalen Thompson J. Thompson	7	27	21	48	1	0.0	2	0	0
Dadrion Taylor-Demerson D. Taylor-Demerson	7	19	14	33	0	0.0	5	2	18	9	18
Max Melton M. Melton	6	16	6	22	1	0.0	4	0	0
Calais Campbell C. Campbell	7	12	7	19	5	3.0	1	0	0
Kei'Trel Clark K. Clark	6	10	7	17	1	0.0	2	0	0
Zaven Collins Z. Collins	7	10	7	17	4	1.0	0	0	0
Dante Stills D. Stills	7	5	11	16	0	0.0	1	0	0
Josh Sweat J. Sweat	7	11	4	15	7	5.0	1	0	0
Will Johnson W. Johnson	5	9	4	13	0	0.0	5	0	0		0
PJ Mustipher	7	7	6	13	1	0.0	1	0	0
Baron Browning B. Browning	7	5	8	13	3	2.0	1	1	4	4	4
Dalvin Tomlinson D. Tomlinson	7	7	5	12	2	0.0	1	0	0
Garrett Williams G. Williams	2	7	4	11	0	0.0	1	0	0
Jordan Burch J. Burch	7	4	6	10	0	0.0	0	0	0
Kitan Crawford K. Crawford	6	5	3	8	0	0.0	1	0	0
Denzel Burke D. Burke	7	5	2	7	0	0.0	3	0	0
Darius Robinson D. Robinson	5	5	2	7	2	1.0	0	0	0
Cody Simon C. Simon	6	3	3	6	0	0.0	0	0	0
Owen Pappoe O. Pappoe	7	2	4	6	0	0.0	0	0	0
Simi Fehoko S. Fehoko	6	3	2	5	0	0.0	0	0	0
Zachary Carter Z. Carter	2	2	3	5	0	0.0	0	0	0
Darren Hall D. Hall	5	1	3	4	0	0.0	0	0	0
Elijah Higgins E. Higgins	7	1	3	4	0	0.0	0	0	0
Anthony Goodlow A. Goodlow	3	1	2	3	1	0.0	0	0	0
Emari Demercado E. Demercado	6	2	0	2	0	0.0	0	0	0
Hjalte Froholdt H. Froholdt	7	2	0	2	0	0.0	0	0	0
Travis Vokolek T. Vokolek	5	2	0	2	0	0.0	0	0	0
Evan Brown E. Brown	6	1	0	1	0	0.0	0	0	0
L.J. Collier	2	1	0	1	0	0.0	0	0	0
Josiah Deguara J. Deguara	2	1	0	1	0	0.0	0	0	0
Bam Knight B. Knight	5	1	0	1	0	0.0	0	0	0
Jonah Williams J. Williams	7	1	0	1	0	0.0	0	0	0
Greg Dortch G. Dortch	7	0	1	1	0	0.0	0	0	0
Bilal Nichols B. Nichols	2	0	1	1	0	0.0	0	0	0