The San Francisco 49ers have a record of 11-4 against the spread in Week 1 between April 15, 2011 and April 15, 2026.

Interpreted as:

49ers week 1 or more ats record last 15 years

	TEAM	DATE	ATS	TM			OPP		RESULT	SPREAD	ATS DIFF	O/U	O/U DIFF	TD	1DWN	OFF	OPP OFF	3DWN%	4DWN%
1	49ers	9/11/2011	1-0	SF	-250	vs	SEA	+210	W 33-17	-6	+10 (Y)	37.5	+12.5 (O)	3	12	209	219	8.3
2	49ers	9/9/2012	1-0	SF	+225	@	GB	-265	W 30-22	+5	+13 (Y)	45	+7 (O)	3	22	377	324	22.2
3	49ers	9/8/2013	1-0	SF	-240	vs	GB	+200	W 34-28	-5	+1 (Y)	47	+15 (O)	4	23	494	385	50.0	100.0
4	49ers	9/7/2014	1-0	SF	-175	@	DAL	+155	W 28-17	-3.5	+7.5 (Y)	49	-4 (U)	4	19	319	382	58.3
5	49ers	9/14/2015	1-0	SF	+120	vs	MIN	-142	W 20-3	+2	+19 (Y)	42	-19 (U)	2	25	395	248	41.7
6	49ers	9/12/2016	1-0	SF	+125	vs	LA	-145	W 28-0	+3	+31 (Y)	42.5	-14.5 (U)	4	28	320	185	47.1	50.0
7	49ers	9/10/2017	0-1	SF	+185	vs	CAR	-200	L 3-23	+4.5	-15.5 (N)	45	-19 (U)	0	13	217	287	18.2	25.0
8	49ers	9/9/2018	0-1	SF	+240	@	MIN	-260	L 16-24	+6	-2 (N)	46.5	-6.5 (U)	1	20	327	343	38.5
9	49ers	9/8/2019	1-0	SF	-104	@	TB	-118	W 31-17	+1	+15 (Y)	51	-3 (U)	3	17	256	295	38.5
10	49ers	9/13/2020	0-1	SF	-312	vs	ARI	+245	L 20-24	-6.5	-10.5 (N)	48	-4 (U)	2	18	366	404	18.2	0.0
11	49ers	9/12/2021	1-0	SF	-371	@	DET	+285	W 41-33	-7.5	+0.5 (Y)	45	+29 (O)	5	21	442	430	33.3
12	49ers	9/11/2022	0-1	SF	-285	@	CHI	+230	L 10-19	-6.5	-15.5 (N)	38	-9 (U)	1	17	331	204	47.1	0.0
13	49ers	9/10/2023	1-0	SF	-121	@	PIT	+102	W 30-7	-1.5	+21.5 (Y)	41.5	-4.5 (U)	3	22	391	239	46.2	100.0
14	49ers	9/9/2024	1-0	SF	-195	vs	NYJ	+163	W 32-19	-3.5	+9.5 (Y)	43	+8 (O)	2	24	401	266	46.2
15	49ers	9/7/2025	1-0	SF	-139	@	SEA	+117	W 17-13	-2.5	+1.5 (Y)	43.5	-13.5 (U)	2	24	384	230	50.0	100.0
	Average		4.9											2.6	20.3	348.6	296.1	39.2	6.1
	Total		11-4											39	305	5,229	4,441	39.2	42.9

StatMuse has team, game-level data for spread records going back to the 1979 season.

More 49ers Stats

Team Leaders

PASS

2,167

Purdy

RUSH

1,202

McCaffrey

REC

924

McCaffrey

Team Rankings

PPG

25.7

10th

OPP PPG

21.8

13th

RUSH YDS/G

106.9

24th

PASS YDS/G

254.0

6th

2025 Division Standings

TEAM	W	L	PCT
Seahawks	14	3	.824
Rams	12	5	.706
49ers	12	5	.706
Cardinals	3	14	.176

Last Game

49ers

1 - 1

Final

Seahawks

1 - 0

Sat 17 Jan 2026

NFL 2025 Leaders

Pass Yards Leaders

4,707

Stafford

4,564

Goff

4,552

Prescott

Rush Yards Leaders

1,621

Cook

1,595

Henry

1,585

Taylor

Rec Yards Leaders

1,793

Smith-Njigba

1,715

Nacua

1,429

Pickens

Pass TD Leaders

46

Stafford

34

Goff

31

Maye

Rush TD Leaders

18

Taylor

16

Henry

14

Allen

Rec TD Leaders

14

Adams

11

McBride

11

St. Brown

QB Rating Leaders

113.5

Maye

109.2

Stafford

105.5

Goff

Sack Leaders

23.0

Garrett

16.5

Burns

15.0

Hunter

NFL 2025 Rankings

PPG Rankings

30.5

28.8

28.4

28.3

27.9

Opp PPG Rankings

17.2

17.4

18.3

18.8

19.1

19.3

Total Yards Rankings

394.6

391.9

379.4

376.3

373.2

369.5

Rush Yards Rankings

159.6

156.6

144.5

134.7

129.1

128.9

Pass Yards Rankings

278.5

276.9

268.6

262.3

256.1

254.0

Sack Leaders

68.0

57.0

53.0

49.0

48.0

NFL Fantasy 2025

Fantasy RB Rankings

316.3

Taylor

314.6

McCaffrey

291.8

Robinson

Fantasy WR Rankings

246

Nacua

240.9

Smith-Njigba

207

St. Brown

Fantasy TE Rankings

189.9

McBride

125.1

Goedert

122.8

Pitts

Fantasy K Rankings

202

Myers

194

Fairbairn

187.6

Aubrey

NFL 2025 Betting

Best Record ATS

15-5

12-6

14-7

12-6-1

12-7

11-7

Worst Record ATS

5-12

5-12-1

6-11

7-10

NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176