The Buffalo Bills have a record of 4-3 against the spread as underdogs in the regular season and playoffs against the AFC South on the road since 2017.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 1/7/2018 | 1-0 | +355 | @ | -400 | L 3-10 | +8.5 | +1.5 (Y) | 40 | -27 (U) | 0 | 20 | 263 | 230 | 38.9 | 100.0 | ||
| 2 | | Bills | 10/14/2018 | 1-0 | +405 | @ | -455 | L 13-20 | +10 | +3 (Y) | 40.5 | -7.5 (U) | 1 | 12 | 229 | 216 | 40.0 | |||
| 3 | | Bills | 10/21/2018 | 0-1 | +260 | @ | -290 | L 5-37 | +7 | -25 (N) | 43.5 | -1.5 (U) | 0 | 15 | 303 | 376 | 22.2 | 0.0 | ||
| 4 | | Bills | 10/6/2019 | 1-0 | +126 | @ | -153 | W 14-7 | +2.5 | +9.5 (Y) | 39.5 | -18.5 (U) | 2 | 18 | 313 | 252 | 30.8 | 50.0 | ||
| 5 | | Bills | 1/4/2020 | 0-1 | +121 | @ | -146 | L 19-22 | +2.5 | -0.5 (N) | 43 | -2 (U) | 1 | 24 | 425 | 360 | 52.4 | 0.0 | ||
| 6 | | Bills | 10/6/2024 | 0-1 | +103 | @ | -122 | L 20-23 | +1.5 | -1.5 (N) | 48 | -5 (U) | 2 | 16 | 276 | 425 | 21.4 | 100.0 | ||
| 7 | | Bills | 1/11/2026 | 1-0 | +106 | @ | -126 | W 27-24 | +1.5 | +4.5 (Y) | 51.5 | -0.5 (U) | 3 | 20 | 340 | 359 | 50.0 | 100.0 | ||
| Average | 8.2 | 1.3 | 17.9 | 307.0 | 316.9 | 38.5 | 0.1 | |||||||||||||
| Total | 4-3 | 9 | 125 | 2,149 | 2,218 | 38.5 | 62.5 |
BUF
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TENStatMuse has team, game-level data for spread records going back to the 1979 season.
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More Bills Stats
Team Leaders 
PASS
334
Allen
RUSH
57
Cook
REC
130
Kincaid
Team Rankings
PPG
36.0
5th
OPP PPG
31.0
22nd
RUSH YDS/G
86.0
24th
PASS YDS/G
334.0
4th
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Dolphins
DET
LAC
LAR
LV
NFL 2026 Leaders
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NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| NFC South | W | L | T | PCT |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 |
Giants
Eagles
Commanders
Cowboys
Vikings
Bears
Packers
Falcons
Buccaneers
Saints
Panthers
49ers
Cardinals
Seahawks| AFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| AFC South | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 1 | 0 | .000 |
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Chiefs