| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 9/12/2021 | 0-1 |  BUF | -286 | vs |  PIT | +229 | L 16-23 | -6.5 | -13.5 (N) | 48.5 | -9.5 (U) | 1 | 22 | 371 | 252 | 44.4 | 33.3 |
| 2 | | Bills | 9/19/2021 | 1-0 | BUF | -188 | @ |  MIA | +159 | W 35-0 | -3.5 | +31.5 (Y) | 48 | -13 (U) | 5 | 21 | 314 | 216 | 53.8 | 100.0 |
| 3 | | Bills | 9/26/2021 | 1-0 | BUF | -346 | vs |  WAS | +270 | W 43-21 | -7 | +15 (Y) | 45.5 | +18.5 (O) | 5 | 29 | 481 | 290 | 60.0 | 0.0 |
| 4 | | Bills | 10/3/2021 | 1-0 | BUF | -1784 | vs |  HOU | +957 | W 40-0 | -19 | +21 (Y) | 47.5 | -7.5 (U) | 4 | 26 | 450 | 109 | 41.7 | 50.0 |
| 5 | | Bills | 10/10/2021 | 1-0 | BUF | +124 | @ |  KC | -146 | W 38-20 | +3 | +21 (Y) | 56.5 | +1.5 (O) | 5 | 20 | 436 | 392 | 45.5 | |
| 6 | | Bills | 10/18/2021 | 0-1 | BUF | -270 | @ |  TEN | +218 | L 31-34 | -6 | -9 (N) | 53.5 | +11.5 (O) | 3 | 28 | 417 | 362 | 53.8 | 0.0 |
| 7 | | Bills | 10/31/2021 | 0-0-1 | BUF | -1046 | vs | MIA | +681 | W 26-11 | -15 | 0 (P) | 48.5 | -11.5 (U) | 3 | 24 | 351 | 262 | 46.2 | 0.0 |
| 8 | | Bills | 11/7/2021 | 0-1 | BUF | -1144 | @ |  JAX | +704 | L 6-9 | -14.5 | -17.5 (N) | 48.5 | -33.5 (U) | 0 | 17 | 301 | 218 | 40.0 | 0.0 |
| 9 | | Bills | 11/14/2021 | 1-0 | BUF | -777 | @ |  NYJ | +533 | W 45-17 | -13.5 | +14.5 (Y) | 48.5 | +13.5 (O) | 6 | 26 | 489 | 366 | 57.1 | |
| 10 | | Bills | 11/21/2021 | 0-1 | BUF | -310 | vs |  IND | +244 | L 15-41 | -7 | -33 (N) | 49.5 | +6.5 (O) | 2 | 19 | 311 | 370 | 50.0 | |
| 11 | | Bills | 11/25/2021 | 1-0 | BUF | -302 | @ |  NO | +239 | W 31-6 | -7 | +18 (Y) | 45 | -8 (U) | 4 | 21 | 361 | 190 | 61.5 | 100.0 |
| 12 | | Bills | 12/6/2021 | 0-1 | BUF | -147 | vs |  NE | +124 | L 10-14 | -3 | -7 (N) | 40 | -16 (U) | 1 | 16 | 230 | 241 | 30.8 | 0.0 |
| 13 | | Bills | 12/12/2021 | 0-1 | BUF | +154 | @ |  TB | -181 | L 27-33 | +3.5 | -2.5 (N) | 52.5 | +7.5 (O) | 3 | 27 | 466 | 488 | 15.4 | 66.7 |
| 14 | | Bills | 12/19/2021 | 1-0 | BUF | -834 | vs |  CAR | +557 | W 31-14 | -14.5 | +2.5 (Y) | 43 | +2 (O) | 4 | 21 | 312 | 275 | 42.9 | 100.0 |
| 15 | | Bills | 12/26/2021 | 1-0 | BUF | -107 | @ | NE | -113 | W 33-21 | +1 | +13 (Y) | 43.5 | +10.5 (O) | 4 | 28 | 428 | 288 | 50.0 | 75.0 |
| 16 | | Bills | 1/2/2022 | 0-0-1 | BUF | -947 | vs |  ATL | +625 | W 29-15 | -14 | 0 (P) | 46 | -2 (U) | 4 | 28 | 351 | 265 | 58.3 | 100.0 |
| 17 | | Bills | 1/9/2022 | 1-0 | BUF | -1163 | vs | NYJ | +714 | W 27-10 | -16 | +1 (Y) | 43 | -6 (U) | 3 | 25 | 424 | 63 | 44.4 | 0.0 |
| 18 | | Bills | 9/8/2022 | 1-0 | BUF | -131 | @ |  LAR | +110 | W 31-10 | -2.5 | +18.5 (Y) | 52 | -11 (U) | 4 | 23 | 413 | 243 | 90.0 | |
| 19 | | Bills | 9/19/2022 | 1-0 | BUF | -453 | vs | TEN | +349 | W 41-7 | -10 | +24 (Y) | 47.5 | +0.5 (O) | 5 | 23 | 414 | 187 | 38.5 | 66.7 |
| 20 | | Bills | 9/25/2022 | 0-1 | BUF | -206 | @ | MIA | +171 | L 19-21 | -4.5 | -6.5 (N) | 54.5 | -14.5 (U) | 2 | 31 | 497 | 212 | 61.1 | 66.7 |
| 21 | | Bills | 10/2/2022 | 0-1 | BUF | -173 | @ |  BAL | +144 | W 23-20 | -3.5 | -0.5 (N) | 50.5 | -7.5 (U) | 2 | 22 | 326 | 296 | 36.4 | 100.0 |
| 22 | | Bills | 10/9/2022 | 1-0 | BUF | -908 | vs | PIT | +611 | W 38-3 | -14 | +21 (Y) | 44.5 | -3.5 (U) | 5 | 21 | 552 | 364 | 55.6 | |
| 23 | | Bills | 10/16/2022 | 1-0 | BUF | -148 | @ | KC | +124 | W 24-20 | -2.5 | +1.5 (Y) | 54 | -10 (U) | 3 | 26 | 443 | 387 | 36.4 | 33.3 |
| 24 | | Bills | 10/30/2022 | 0-1 | BUF | -502 | vs |  GB | +381 | W 27-17 | -10.5 | -0.5 (N) | 47 | -3 (U) | 3 | 20 | 369 | 398 | 28.6 | |
| 25 | | Bills | 11/6/2022 | 0-1 | BUF | -562 | @ | NYJ | +410 | L 17-20 | -10.5 | -13.5 (N) | 46 | -9 (U) | 2 | 19 | 317 | 310 | 61.5 | 0.0 |
| Average | 0.7 | 3.4 | 22.5 | 378.8 | 310.3 | 47.4 | 1.2 | |||||||||||||
| Total | 38-35-2 | 258 | 1,691 | 28,409 | 23,271 | 47.4 | 58.2 | |||||||||||||
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