The Buffalo Bills are 12-14-1 against the spread in the regular season against the AFC East at home since 2017.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 9/10/2017 | 1-0 | -360 | vs | +325 | W 21-12 | -7.5 | +1.5 (Y) | 42.5 | -9.5 (U) | 3 | 23 | 408 | 214 | 47.1 | |||
| 2 | | Bills | 12/3/2017 | 0-1 | +305 | vs | -335 | L 3-23 | +7.5 | -12.5 (N) | 49 | -23 (U) | 0 | 16 | 268 | 435 | 38.5 | 0.0 | ||
| 3 | | Bills | 12/17/2017 | 1-0 | -185 | vs | +170 | W 24-16 | -3.5 | +4.5 (Y) | 39.5 | +0.5 (O) | 3 | 21 | 328 | 349 | 46.7 | 0.0 | ||
| 4 | | Bills | 10/29/2018 | 0-1 | +750 | vs | -950 | L 6-25 | +14 | -5 (N) | 44 | -13 (U) | 0 | 16 | 333 | 387 | 28.6 | 0.0 | ||
| 5 | | Bills | 12/9/2018 | 0-1 | -205 | vs | +188 | L 23-27 | -4.5 | -8.5 (N) | 37 | +13 (O) | 2 | 24 | 368 | 248 | 50.0 | |||
| 6 | | Bills | 12/30/2018 | 1-0 | -240 | vs | +220 | W 42-17 | -5.5 | +19.5 (Y) | 39.5 | +19.5 (O) | 6 | 23 | 381 | 225 | 45.5 | 50.0 | ||
| 7 | | Bills | 9/29/2019 | 1-0 | +253 | vs | -314 | L 10-16 | +7 | +1 (Y) | 41.5 | -15.5 (U) | 1 | 23 | 375 | 224 | 15.4 | 50.0 | ||
| 8 | | Bills | 10/20/2019 | 0-1 | -1336 | vs | +802 | W 31-21 | -17 | -7 (N) | 42 | +10 (O) | 3 | 17 | 305 | 381 | 30.0 | |||
| 9 | | Bills | 12/29/2019 | 0-1 | -105 | vs | -115 | L 6-13 | +1 | -6 (N) | 37 | -18 (U) | 0 | 17 | 309 | 271 | 28.6 | |||
| 10 | | Bills | 9/13/2020 | 1-0 | -294 | vs | +235 | W 27-17 | -6.5 | +3.5 (Y) | 39.5 | +4.5 (O) | 3 | 31 | 404 | 254 | 50.0 | 100.0 | ||
| 11 | | Bills | 11/1/2020 | 0-1 | -206 | vs | +172 | W 24-21 | -4 | -1 (N) | 41 | +4 (O) | 3 | 22 | 339 | 349 | 45.5 | |||
| 12 | | Bills | 1/3/2021 | 1-0 | +144 | vs | -171 | W 56-26 | +3.5 | +33.5 (Y) | 43 | +39 (O) | 8 | 24 | 455 | 454 | 40.0 | |||
| 13 | | Bills | 10/31/2021 | 0-0-1 | -1046 | vs | +681 | W 26-11 | -15 | 0 (P) | 48.5 | -11.5 (U) | 3 | 24 | 351 | 262 | 46.2 | 0.0 | ||
| 14 | | Bills | 12/6/2021 | 0-1 | -147 | vs | +124 | L 10-14 | -3 | -7 (N) | 40 | -16 (U) | 1 | 16 | 230 | 241 | 30.8 | 0.0 | ||
| 15 | | Bills | 1/9/2022 | 1-0 | -1163 | vs | +714 | W 27-10 | -16 | +1 (Y) | 43 | -6 (U) | 3 | 25 | 424 | 63 | 44.4 | 0.0 | ||
| 16 | | Bills | 12/11/2022 | 0-1 | -462 | vs | +356 | W 20-12 | -10 | -2 (N) | 43.5 | -11.5 (U) | 2 | 14 | 232 | 309 | 15.4 | |||
| 17 | | Bills | 12/17/2022 | 0-1 | -349 | vs | +273 | W 32-29 | -7 | -4 (N) | 44.5 | +16.5 (O) | 4 | 29 | 446 | 405 | 57.1 | |||
| 18 | | Bills | 1/8/2023 | 1-0 | -390 | vs | +306 | W 35-23 | -8 | +4 (Y) | 44.5 | +13.5 (O) | 5 | 18 | 327 | 341 | 58.3 | |||
| 19 | | Bills | 10/1/2023 | 1-0 | -150 | vs | +127 | W 48-20 | -3 | +25 (Y) | 52.5 | +15.5 (O) | 6 | 24 | 414 | 393 | 50.0 | |||
| 20 | | Bills | 11/19/2023 | 1-0 | -419 | vs | +323 | W 32-6 | -8.5 | +17.5 (Y) | 39 | -1 (U) | 3 | 22 | 393 | 155 | 38.5 | 100.0 | ||
| 21 | | Bills | 12/31/2023 | 0-1 | -1045 | vs | +667 | W 27-21 | -15 | -9 (N) | 40 | +8 (O) | 3 | 19 | 281 | 294 | 46.7 | |||
| 22 | | Bills | 11/3/2024 | 0-1 | -279 | vs | +225 | W 30-27 | -6 | -3 (N) | 49 | +8 (O) | 3 | 24 | 325 | 373 | 50.0 | 100.0 | ||
| 23 | | Bills | 12/22/2024 | 0-1 | -1136 | vs | +720 | W 24-21 | -14 | -11 (N) | 48 | -3 (U) | 3 | 19 | 324 | 379 | 36.4 | 100.0 | ||
| 24 | | Bills | 12/29/2024 | 1-0 | -552 | vs | +408 | W 40-14 | -10.5 | +15.5 (Y) | 44.5 | +9.5 (O) | 5 | 23 | 348 | 281 | 57.1 | 0.0 | ||
| 25 | | Bills | 9/18/2025 | 0-1 | -787 | vs | +548 | W 31-21 | -11.5 | -1.5 (N) | 50.5 | +1.5 (O) | 4 | 23 | 360 | 276 | 54.5 | |||
| Average | 1.7 | 3.1 | 21.9 | 354.1 | 297.1 | 42.6 | 0.0 | |||||||||||||
| Total | 12-14-1 | 84 | 592 | 9,561 | 8,023 | 42.6 | 39.1 | |||||||||||||
BUF
NYJ
NE
MIA
NYJ
NYJStatMuse has team, game-level data for spread records going back to the 1979 season.
More NFL News
Jaxson Dart and Isaiah Likely show off their chemistry in Giants' Week 1 win
Packers seeking answers on offensive line after failing to protect Love in season-opening collapse
Bears score 59 points in opening win despite quiet days for a couple of Williams' top targets
Falcons' quarterback questions persist after shaky effort by Cooper Rush in opening loss to Steelers
Todd Monken stands by Deshaun Watson after his performance in Browns’ opening loss sparks fan outcry
McCarthy stays vague as Steelers sit Joey Porter Jr. amid back rehab, contract limbo
More Bills Stats
Team Leaders 
PASS
334
Allen
RUSH
57
Cook
REC
130
Kincaid
Team Rankings
PPG
36.0
5th
OPP PPG
31.0
22nd
RUSH YDS/G
86.0
24th
PASS YDS/G
334.0
4th
DET
LAC
LAR
LV
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| NFC South | W | L | T | PCT |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 |
Giants
Eagles
Commanders
Cowboys
Vikings
Bears
Packers
Falcons
Buccaneers
Saints
Panthers
49ers
Cardinals
Seahawks| AFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| AFC South | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 1 | 0 | .000 |
Ravens
Steelers
Bengals
Browns
Jaguars
Texans
Titans
Colts
Chiefs
Broncos