LeSean McCoy had the most yards from scrimmage for the Bills in a Week-2 game in 2018, with 68 yards against the Chargers on September 16, 2018.
| NAME | YDS | DATE | TM | OPP | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | L. McCoy | 68 | 9/16/2018 |  BUF | vs |  LAC | 39 | 9 | 4.3 | 0 | 29 | 4 | 4 | 7.3 | 0 |
| 2 |  | Z. Jones | 63 | 9/16/2018 | BUF | vs | LAC | 0 | 0 | 0 | 63 | 2 | 3 | 31.5 | 0 | |
| 3 |  | C. Ivory | 37 | 9/16/2018 | BUF | vs | LAC | 7 | 2 | 3.5 | 1 | 30 | 1 | 2 | 30.0 | 0 |
| 4 |  | J. Allen | 32 | 9/16/2018 | BUF | vs | LAC | 32 | 8 | 4.0 | 0 | 0 | 0 | 0 | 0 | |
| 5 | | R. Foster | 30 | 9/16/2018 | BUF | vs | LAC | 0 | 0 | 0 | 30 | 2 | 3 | 15.0 | 0 | |
| 6 | | C. Clay | 29 | 9/16/2018 | BUF | vs | LAC | 0 | 0 | 0 | 29 | 2 | 3 | 14.5 | 0 | |
| 7 | | P. DiMarco | 24 | 9/16/2018 | BUF | vs | LAC | 0 | 0 | 0 | 24 | 1 | 1 | 24.0 | 0 | |
| 8 | | K. Benjamin | 19 | 9/16/2018 | BUF | vs | LAC | 0 | 0 | 0 | 19 | 2 | 3 | 9.5 | 1 | |
| 9 | | M. Murphy | 13 | 9/16/2018 | BUF | vs | LAC | 6 | 3 | 2.0 | 0 | 7 | 1 | 5 | 7.0 | 0 |
| 10 | | L. Thomas | 7 | 9/16/2018 | BUF | vs | LAC | 0 | 0 | 0 | 7 | 1 | 1 | 7.0 | 0 | |
| 11 | | J. Croom | 7 | 9/16/2018 | BUF | vs | LAC | 0 | 0 | 0 | 7 | 2 | 4 | 3.5 | 0 |
More Bills Stats
Team Rankings
PPG
30.9
2nd
OPP PPG
21.6
11th
RUSH YDS/G
131.2
9th
PASS YDS/G
231.6
17th
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| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 14 | 3 | 0 | .824 |
 Commanders | 12 | 5 | 0 | .706 |
| NFC North | W | L | T | PCT |
 Lions | 15 | 2 | 0 | .882 |
 Vikings | 14 | 3 | 0 | .824 |
| NFC South | W | L | T | PCT |
 Buccaneers | 10 | 7 | 0 | .588 |
 Falcons | 8 | 9 | 0 | .471 |
| NFC West | W | L | T | PCT |
 Rams | 10 | 7 | 0 | .588 |
 Seahawks | 10 | 7 | 0 | .588 |
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