The Buffalo Bills have a record of 4-6 against the spread as favorites on the road in their last 10 games.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 12/8/2024 | 0-1 | -191 | @ | +158 | L 42-44 | -3.5 | -5.5 (N) | 50 | +36 (O) | 6 | 25 | 445 | 457 | 55.6 | |||
| 2 | | Bills | 1/5/2025 | 0-1 | -173 | @ | +145 | L 16-23 | -3 | -10 (N) | 36.5 | +2.5 (O) | 2 | 16 | 259 | 309 | 40.0 | 25.0 | ||
| 3 | | Bills | 9/14/2025 | 1-0 | -283 | @ | +230 | W 30-10 | -6 | +14 (Y) | 47.5 | -7.5 (U) | 3 | 25 | 403 | 154 | 35.7 | 100.0 | ||
| 4 | | Bills | 10/13/2025 | 0-1 | -203 | @ | +169 | L 14-24 | -3.5 | -13.5 (N) | 49.5 | -11.5 (U) | 2 | 17 | 291 | 443 | 22.2 | 0.0 | ||
| 5 | | Bills | 10/26/2025 | 1-0 | -398 | @ | +314 | W 40-9 | -7.5 | +23.5 (Y) | 47.5 | +1.5 (O) | 5 | 23 | 410 | 244 | 58.3 | |||
| 6 | | Bills | 11/9/2025 | 0-1 | -455 | @ | +350 | L 13-30 | -7.5 | -24.5 (N) | 50 | -7 (U) | 2 | 20 | 376 | 370 | 33.3 | 50.0 | ||
| 7 | | Bills | 11/20/2025 | 0-1 | -235 | @ | +193 | L 19-23 | -4.5 | -8.5 (N) | 44 | -2 (U) | 2 | 14 | 326 | 261 | 31.3 | 60.0 | ||
| 8 | | Bills | 11/30/2025 | 1-0 | -175 | @ | +145 | W 26-7 | -3 | +16 (Y) | 44.5 | -11.5 (U) | 3 | 26 | 372 | 166 | 53.3 | 100.0 | ||
| 9 | | Bills | 12/14/2025 | 1-0 | -139 | @ | +119 | W 35-31 | -2.5 | +1.5 (Y) | 49.5 | +16.5 (O) | 5 | 22 | 349 | 385 | 57.1 | 100.0 | ||
| 10 | | Bills | 12/21/2025 | 0-1 | -599 | @ | +442 | W 23-20 | -10.5 | -7.5 (N) | 41.5 | +1.5 (O) | 3 | 16 | 259 | 294 | 25.0 | 0.0 | ||
| Average | 4.0 | 3.3 | 20.4 | 349.0 | 308.3 | 41.7 | 0.1 | |||||||||||||
| Total | 4-6 | 33 | 204 | 3,490 | 3,083 | 41.7 | 52.6 |
BUF
LAR
NE
NYJ
ATL
CAR
MIA
HOU
PIT
CLEStatMuse has team, game-level data for spread records going back to the 1979 season.
More NFL News
Myles Garrett acknowledges knee injury is significant after 0-tackle debut in Rams' Australia loss
Rams receiver Puka Nacua acknowledges struggles with alcohol in Netflix interview
49ers rout Rams 27-7 in NFL's first Australia game behind Brock Purdy's 3 TD passes
49ers rookie WR De'Zhaun Stribling ruled out with an ankle injury
Cowboys reach $18 million, 3-year deal with backup tight end Brevyn Spann-Ford
Patriots have plenty of issues after Brown's injury, Maye's turnovers marred season-opening loss
More Bills Stats
DET
LACNFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 0 | 0 | ||
| NFC North | W | L | T | PCT |
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 0 | 0 | ||
| NFC South | W | L | T | PCT |
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 0 | 0 | ||
0 | 0 | 0 | ||
| NFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 0 | 0 | ||
0 | 1 | 0 | .000 |
Giants
Cowboys
Commanders
Eagles
Vikings
Packers
Bears
Buccaneers
Saints
49ers
Seahawks
Cardinals
Bengals
Ravens
Titans
Jaguars
Colts
Chiefs
Broncos
Raiders