Between the 2000 and 2009 seasons, Willis McGahee had the most total touchdowns for the Bills in a game, with 4 touchdowns versus the Seahawks on November 28, 2004.
Interpreted as:
buffalo bills player most touchdowns in a regular-season game 2000s| NAME | TD | DATE | TM | OPP | RUSH TD | REC TD | RET TD | FGM | XPM | XP2 | SFTY | PTS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | W. McGahee | 4 | 11/28/2004 | @ | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 24 | ||
| 2 | | L. Evans | 3 | 12/4/2005 | @ | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 18 | ||
| 3 | | M. Campbell | 3 | 11/21/2004 | vs | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 18 | ||
| 4 | | T. Henry | 3 | 9/14/2003 | @ | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 18 | ||
| 5 | | T. Henry | 3 | 9/8/2002 | vs | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 18 | ||
| 6 | | A. Smith | 3 | 12/23/2000 | @ | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 18 | ||
| 7 | | F. Jackson | 2 | 11/29/2009 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 8 | | L. Evans | 2 | 11/15/2009 | @ | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 9 | | T. Edwards | 2 | 11/23/2008 | @ | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 10 |  | M. Lynch | 2 | 9/21/2008 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 11 | | L. Evans | 2 | 12/9/2007 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 12 | | R. Royal | 2 | 12/9/2007 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 13 | | W. McGahee | 2 | 11/26/2006 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 14 | | L. Evans | 2 | 11/19/2006 | @ | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 15 | | T. McGee | 2 | 12/24/2005 | @ | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 12 | ||
| 16 | | L. Evans | 2 | 11/13/2005 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 17 | | W. McGahee | 2 | 1/2/2005 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 18 | | L. Evans | 2 | 12/26/2004 | @ | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 19 | | W. McGahee | 2 | 12/26/2004 | @ | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 20 | | W. McGahee | 2 | 12/12/2004 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 21 | | L. Evans | 2 | 12/5/2004 | @ | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 22 | | W. McGahee | 2 | 10/31/2004 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 23 | | T. Henry | 2 | 10/19/2003 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 24 | | T. Henry | 2 | 10/5/2003 | vs | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 25 | | T. Henry | 2 | 9/7/2003 | vs | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 12 | ||
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3,668
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1,621
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719
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Team Rankings
PPG
28.3
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OPP PPG
21.5
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RUSH YDS/G
159.6
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PASS YDS/G
234.2
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NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |