The Arizona Cardinals had a record of 19-21-1 against the spread against the AFC between the 2012 and 2021 seasons.
| TEAM | DATE | ATS | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Cardinals | 9/16/2012 | 1-0 | +650 | @ | -850 | W 20-18 | +12.5 | +14.5 (Y) | 48 | -10 (U) | 2 | 16 | 242 | 387 | 28.6 | |||
| 2 | | Cardinals | 9/30/2012 | 0-1 | -220 | vs | +190 | W 24-21 | -4.5 | -1.5 (N) | 39.5 | +5.5 (O) | 3 | 19 | 297 | 480 | 25.0 | 100.0 | ||
| 3 | | Cardinals | 10/14/2012 | 0-1 | -240 | vs | +200 | L 16-19 | -5 | -8 (N) | 44.5 | -9.5 (U) | 1 | 20 | 332 | 306 | 31.3 | 100.0 | ||
| 4 | | Cardinals | 12/2/2012 | 1-0 | +230 | @ | -270 | L 6-7 | +6 | +5 (Y) | 37 | -24 (U) | 0 | 5 | 137 | 289 | 0.0 | 50.0 | ||
| 5 | | Cardinals | 11/10/2013 | 0-1 | -200 | vs | +170 | W 27-24 | -3.5 | -0.5 (N) | 42 | +9 (O) | 3 | 19 | 332 | 235 | 30.0 | |||
| 6 | | Cardinals | 11/17/2013 | 1-0 | -440 | @ | +360 | W 27-14 | -9.5 | +3.5 (Y) | 40.5 | +0.5 (O) | 3 | 19 | 416 | 274 | 31.3 | |||
| 7 | | Cardinals | 11/24/2013 | 1-0 | -165 | vs | +145 | W 40-11 | -3 | +26 (Y) | 44.5 | +6.5 (O) | 4 | 27 | 410 | 239 | 50.0 | |||
| 8 | | Cardinals | 12/15/2013 | 0-0-1 | -150 | @ | +130 | W 37-34 | -3 | 0 (P) | 43 | +28 (O) | 4 | 24 | 360 | 460 | 50.0 | |||
| 9 | | Cardinals | 9/8/2014 | 0-1 | -155 | vs | +135 | W 18-17 | -3 | -2 (N) | 46.5 | -11.5 (U) | 2 | 22 | 403 | 290 | 46.2 | |||
| 10 | | Cardinals | 10/5/2014 | 0-1 | +330 | @ | -400 | L 20-41 | +8.5 | -12.5 (N) | 47 | +14 (O) | 2 | 9 | 215 | 568 | 18.8 | |||
| 11 | | Cardinals | 10/19/2014 | 1-0 | -175 | @ | +155 | W 24-13 | -3.5 | +7.5 (Y) | 44 | -7 (U) | 3 | 25 | 365 | 220 | 60.0 | 0.0 | ||
| 12 | | Cardinals | 12/7/2014 | 1-0 | +130 | vs | -150 | W 17-14 | +2 | +5 (Y) | 41 | -10 (U) | 1 | 18 | 366 | 390 | 40.0 | |||
| 13 | | Cardinals | 10/18/2015 | 0-1 | -230 | @ | +205 | L 13-25 | -6 | -18 (N) | 46 | -8 (U) | 1 | 21 | 469 | 310 | 41.7 | 0.0 | ||
| 14 | | Cardinals | 10/26/2015 | 0-1 | -500 | vs | +400 | W 26-18 | -10 | -2 (N) | 50 | -6 (U) | 3 | 21 | 414 | 276 | 41.7 | |||
| 15 | | Cardinals | 11/1/2015 | 1-0 | -320 | @ | +260 | W 34-20 | -7 | +7 (Y) | 46 | +8 (O) | 4 | 25 | 491 | 254 | 81.3 | |||
| 16 | | Cardinals | 11/22/2015 | 0-1 | -215 | vs | +185 | W 34-31 | -4 | -1 (N) | 48 | +17 (O) | 4 | 21 | 383 | 377 | 45.5 | |||
| 17 | | Cardinals | 9/11/2016 | 0-1 | -400 | vs | +300 | L 21-23 | -9 | -11 (N) | 45 | -1 (U) | 3 | 21 | 344 | 363 | 50.0 | |||
| 18 | | Cardinals | 9/25/2016 | 0-1 | -215 | @ | +185 | L 18-33 | -4.5 | -19.5 (N) | 48 | +3 (O) | 2 | 25 | 348 | 297 | 33.3 | 0.0 | ||
| 19 | | Cardinals | 10/17/2016 | 1-0 | -335 | vs | +280 | W 28-3 | -7 | +18 (Y) | 45.5 | -14.5 (U) | 4 | 28 | 396 | 230 | 54.5 | |||
| 20 | | Cardinals | 12/11/2016 | 0-1 | -128 | @ | +108 | L 23-26 | -2 | -5 (N) | 44 | +5 (O) | 3 | 21 | 300 | 314 | 30.8 | |||
| 21 | | Cardinals | 9/17/2017 | 0-1 | -310 | @ | +260 | W 16-13 | -7 | -4 (N) | 44 | -15 (U) | 1 | 17 | 389 | 266 | 40.0 | 0.0 | ||
| 22 | | Cardinals | 11/19/2017 | 0-1 | +119 | @ | -129 | L 21-31 | +2.5 | -7.5 (N) | 38.5 | +13.5 (O) | 3 | 17 | 292 | 357 | 30.0 | 0.0 | ||
| 23 | | Cardinals | 11/26/2017 | 1-0 | +230 | vs | -250 | W 27-24 | +6 | +9 (Y) | 37 | +14 (O) | 2 | 20 | 344 | 219 | 41.2 | |||
| 24 | | Cardinals | 12/10/2017 | 1-0 | +130 | vs | -140 | W 12-7 | +2.5 | +7.5 (Y) | 42 | -23 (U) | 0 | 16 | 261 | 204 | 21.4 | |||
| 25 | | Cardinals | 10/18/2018 | 0-1 | -105 | vs | -105 | L 10-45 | +1 | -34 (N) | 42 | +13 (O) | 1 | 14 | 223 | 309 | 28.6 | 0.0 | ||
| Average | 1.2 | 2.6 | 20.3 | 351.2 | 317.3 | 38.9 | 0.0 | |||||||||||||
| Total | 19-21-1 | 107 | 834 | 14,400 | 13,011 | 38.9 | 55.9 | |||||||||||||
NYJStatMuse has team, game-level data for spread records going back to the 1979 season.
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More Cardinals Stats
Team Leaders 
PASS
3,366
Brissett
RUSH
333
Carter
REC
1,239
McBride
Team Rankings
PPG
20.9
23rd
OPP PPG
28.7
29th
RUSH YDS/G
93.1
31st
PASS YDS/G
256.1
5th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |