The Carolina Panthers had their lowest point differential in a game against the Oakland Raiders on December 24, 2000, with a -43-point differential.
Interpreted as:
carolina panthers biggest loss in a regular-season game of all-time| TEAM | DIFF | DATE | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Panthers | -43 | 12/24/2000 |  CAR | @ |  OAK | L 9-52 | 0 | 19 | 297 | 409 | 50.0 | |
| 2 | | Panthers | -41 | 11/24/2002 | CAR | vs |  ATL | L 0-41 | 0 | 10 | 122 | 426 | 20.0 | |
| 3 | | Panthers | -38 | 10/27/2019 | CAR | @ |  SF | L 13-51 | 1 | 12 | 230 | 388 | 15.4 | 0.0 |
| 4 | | Panthers | -37 | 9/8/2024 | CAR | @ |  NO | L 10-47 | 1 | 11 | 193 | 379 | 10.0 | 33.3 |
| 5 | | Panthers | -34 | 12/29/2024 | CAR | @ |  TB | L 14-48 | 2 | 13 | 204 | 551 | 22.2 | 0.0 |
| 6 | | Panthers | -34 | 12/17/2006 | CAR | vs |  PIT | L 3-37 | 0 | 12 | 240 | 306 | 23.1 | 50.0 |
| 7 | | Panthers | -34 | 11/11/2001 | CAR | @ |  STL | L 14-48 | 2 | 8 | 146 | 493 | 9.1 | 0.0 |
| 8 | | Panthers | -34 | 11/9/1997 | CAR | @ |  DEN | L 0-34 | 0 | 7 | 147 | 393 | 23.1 | |
| 9 | | Panthers | -33 | 10/20/2024 | CAR | @ |  WAS | L 7-40 | 1 | 10 | 180 | 421 | 30.0 | 0.0 |
| 10 | | Panthers | -33 | 12/4/2016 | CAR | @ |  SEA | L 7-40 | 1 | 14 | 271 | 534 | 41.7 | 0.0 |
| 11 | | Panthers | -32 | 12/29/2019 | CAR | vs | NO | L 10-42 | 1 | 16 | 329 | 379 | 31.3 | 50.0 |
| 12 | | Panthers | -32 | 12/22/2019 | CAR | @ |  IND | L 6-38 | 0 | 19 | 286 | 324 | 28.6 | 50.0 |
| 13 | | Panthers | -32 | 1/6/2002 | CAR | vs |  NE | L 6-38 | 0 | 18 | 322 | 298 | 30.8 | 0.0 |
| 14 | | Panthers | -31 | 11/8/2018 | CAR | @ | PIT | L 21-52 | 3 | 18 | 242 | 457 | 36.4 | 100.0 |
| 15 | | Panthers | -31 | 11/7/2010 | CAR | vs | NO | L 3-34 | 0 | 15 | 195 | 408 | 8.3 | 50.0 |
| 16 | | Panthers | -31 | 12/9/2007 | CAR | @ |  JAX | L 6-37 | 0 | 10 | 149 | 427 | 16.7 | 33.3 |
| 17 | | Panthers | -30 | 10/20/2002 | CAR | @ | ATL | L 0-30 | 0 | 12 | 205 | 393 | 27.3 | 0.0 |
| 18 | | Panthers | -29 | 9/20/2012 | CAR | vs |  NYG | L 7-36 | 1 | 22 | 327 | 405 | 44.4 | 0.0 |
| 19 | | Panthers | -28 | 9/28/2014 | CAR | @ |  BAL | L 10-38 | 1 | 20 | 315 | 454 | 66.7 | |
| 20 | | Panthers | -28 | 1/1/2012 | CAR | @ | NO | L 17-45 | 2 | 21 | 301 | 617 | 0.0 | |
| 21 | | Panthers | -28 | 9/13/2009 | CAR | vs |  PHI | L 10-38 | 1 | 14 | 169 | 267 | 18.8 | 66.7 |
| 22 | | Panthers | -28 | 10/4/1998 | CAR | @ | ATL | L 23-51 | 3 | 16 | 346 | 323 | 33.3 | 50.0 |
| 23 | | Panthers | -27 | 11/13/2011 | CAR | vs |  TEN | L 3-30 | 0 | 16 | 279 | 383 | 21.4 | |
| 24 | | Panthers | -27 | 11/29/1998 | CAR | @ |  NYJ | L 21-48 | 3 | 15 | 216 | 456 | 30.0 | 100.0 |
| 25 | | Panthers | -26 | 10/6/2024 | CAR | @ |  CHI | L 10-36 | 1 | 14 | 292 | 424 | 25.0 | 33.3 |
More Panthers Stats
Team Rankings
PPG
20.7
19th
OPP PPG
17.7
8th
RUSH YDS/G
90.7
25th
PASS YDS/G
201.0
23rd
2025 Division Standings
| TEAM | W | L | T | PCT |
|---|---|---|---|---|
| Buccaneers | 3 | 0 | 0 | 1.000 |
| Falcons | 1 | 2 | 0 | .333 |
| Panthers | 1 | 2 | 0 | .333 |
| Saints | 0 | 3 | 0 | .000 |
MIA 
DAL 
NYJ 
BUF 
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
| Eagles | 3 | 0 | 0 | 1.000 |
| Commanders | 2 | 1 | 0 | .667 |
| NFC North | W | L | T | PCT |
 Packers | 2 | 1 | 0 | .667 |
 Vikings | 2 | 1 | 0 | .667 |
| NFC South | W | L | T | PCT |
| Buccaneers | 3 | 0 | 0 | 1.000 |
| Panthers | 1 | 2 | 0 | .333 |
| NFC West | W | L | T | PCT |
| 49ers | 3 | 0 | 0 | 1.000 |
 Rams | 2 | 1 | 0 | .667 |
Bengals 
Chargers 
KC 
ARI 
HOU 
CLE 
DET 
