The Los Angeles Chargers are 22-10-1 against the Bills in the regular season and playoffs on Sundays all-time.
| TEAM | DATE | REC | TM | OPP | RESULT | W% | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Chargers | 10/2/1960 | 1-0 | @ | W 24-10 | 1.000 | 3 | 12 | 159 | 238 | ||||
| 2 | | Chargers | 11/20/1960 | 0-1 | vs | L 3-32 | .000 | 0 | 11 | 185 | 248 | ||||
| 3 | | Chargers | 12/10/1961 | 1-0 | vs | W 28-10 | 1.000 | 4 | 7 | 237 | 279 | ||||
| 4 | | Chargers | 11/11/1962 | 0-1 | vs | L 20-40 | .000 | 3 | 21 | 370 | 335 | ||||
| 5 | | Chargers | 9/8/1963 | 1-0 | vs | W 14-10 | 1.000 | 2 | 17 | 370 | 306 | ||||
| 6 | | Chargers | 11/17/1963 | 1-0 | @ | W 23-13 | 1.000 | 2 | 16 | 355 | 358 | ||||
| 7 | | Chargers | 10/10/1965 | 1-0 | @ | W 34-3 | 1.000 | 4 | 18 | 458 | 150 | ||||
| 8 | | Chargers | 12/26/1965 | 0-1 | vs | L 0-23 | .000 | 0 | 12 | 223 | 260 | ||||
| 9 | | Chargers | 9/4/1966 | 1-0 | vs | W 27-7 | 1.000 | 3 | 15 | 290 | 267 | ||||
| 10 | | Chargers | 10/16/1966 | 0-0-1 | @ | T 17-17 | .500 | 2 | 12 | 219 | 320 | ||||
| 11 | | Chargers | 10/1/1967 | 1-0 | @ | W 37-17 | 1.000 | 4 | 26 | 484 | 247 | ||||
| 12 | | Chargers | 11/17/1968 | 1-0 | @ | W 21-6 | 1.000 | 3 | 15 | 282 | 151 | ||||
| 13 | | Chargers | 12/14/1969 | 1-0 | vs | W 45-6 | 1.000 | 6 | 30 | 537 | 238 | ||||
| 14 | | Chargers | 9/23/1973 | 1-0 | vs | W 34-7 | 1.000 | 5 | 17 | 354 | 287 | ||||
| 15 | | Chargers | 11/21/1976 | 1-0 | @ | W 34-13 | 1.000 | 4 | 20 | 382 | 219 | ||||
| 16 | | Chargers | 9/16/1979 | 1-0 | vs | W 27-19 | 1.000 | 4 | 18 | 339 | 298 | ||||
| 17 | | Chargers | 10/5/1980 | 0-1 | vs | L 24-26 | .000 | 3 | 19 | 300 | 202 | ||||
| 18 | | Chargers | 12/6/1981 | 0-1 | vs | L 27-28 | .000 | 3 | 28 | 482 | 318 | ||||
| 19 | | Chargers | 9/8/1985 | 1-0 | @ | W 14-9 | 1.000 | 2 | 17 | 308 | 455 | ||||
| 20 | | Chargers | 12/1/1985 | 1-0 | vs | W 40-7 | 1.000 | 5 | 21 | 365 | 347 | ||||
| 21 | | Chargers | 9/6/1998 | 1-0 | vs | W 16-14 | 1.000 | 1 | 14 | 254 | 297 | 20.0 | |||
| 22 | | Chargers | 10/15/2000 | 0-1 | @ | L 24-27 | .000 | 3 | 15 | 303 | 424 | 35.7 | |||
| 23 | | Chargers | 10/28/2001 | 1-0 | vs | W 27-24 | 1.000 | 3 | 17 | 338 | 396 | 27.3 | |||
| 24 | | Chargers | 12/15/2002 | 0-1 | @ | L 13-20 | .000 | 1 | 14 | 308 | 256 | 27.8 | 0.0 | ||
| 25 | | Chargers | 11/20/2005 | 1-0 | vs | W 48-10 | 1.000 | 6 | 28 | 478 | 202 | 54.5 | 100.0 | ||
| Average | .682 | 3.1 | 18.5 | 338.5 | 292.1 | ||||||||||
| Total | 22-10-1 | .682 | 101 | 609 | 11,170 | 9,639 | |||||||||
LAC
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More Chargers Stats
Team Leaders 
PASS
816
Herbert
RUSH
238
Hampton
REC
209
Harris
Team Rankings
PPG
16.8
29th
OPP PPG
26.5
24th
RUSH YDS/G
121.5
10th
PASS YDS/G
204.0
23rd
Chiefs
Raiders
Broncos
LAR
HOU
BAL
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 3 | 0 | .400 | |
1 | 3 | 0 | .250 | |
| NFC North | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| NFC South | W | L | T | PCT |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
1 | 4 | 0 | .200 | |
| NFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 |
Giants
Eagles
Cowboys
Commanders
Vikings
Bears
Lions
Packers
Panthers
Falcons
Saints
Buccaneers
49ers
Seahawks
Cardinals| AFC East | W | L | T | PCT |
|---|---|---|---|---|
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
1 | 3 | 0 | .250 | |
0 | 4 | 0 | .000 | |
| AFC North | W | L | T | PCT |
3 | 1 | 0 | .750 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
2 | 2 | 0 | .500 | |
| AFC South | W | L | T | PCT |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 | |
0 | 4 | 0 | .000 | |
| AFC West | W | L | T | PCT |
4 | 0 | 0 | 1.000 | |
3 | 1 | 0 | .750 | |
2 | 2 | 0 | .500 | |
0 | 4 | 0 | .000 |
Patriots
Jets
Dolphins
Browns
Steelers
Bengals
Jaguars
Colts
Titans