Answered February 24th, 2020
Eli Manning had his most passing touchdowns in a game against the Cowboys on September 8, 2013, on October 25, 2010 and on September 9, 2007, with 4 touchdowns.
Eli Manning had his most passing touchdowns in a game against the Cowboys on September 8, 2013, on October 25, 2010 and on September 9, 2007, with 4 touchdowns.