The Buffalo Bills had the highest point differential by a team in a 2021 playoff game, with a 30-point differential in the 2021 AFC Wild Card game versus the Patriots on January 15, 2022.
| TEAM | DIFF | DATE | ROUND | TM | OPP | RESULT | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 30 | 1/15/2022 | AFC Wild Card | vs | W 47-17 | 7 | 29 | 482 | 305 | 85.7 | |||
| 2 |  | Rams | 23 | 1/17/2022 | NFC Wild Card | vs | W 34-11 | 4 | 16 | 375 | 183 | 46.2 | |||
| 3 |  | Chiefs | 21 | 1/16/2022 | AFC Wild Card | vs | W 42-21 | 6 | 26 | 478 | 257 | 66.7 | |||
| 4 |  | Buccaneers | 16 | 1/16/2022 | NFC Wild Card | vs | W 31-15 | 4 | 23 | 349 | 339 | 30.8 | 0.0 | ||
| 5 |  | Bengals | 7 | 1/15/2022 | AFC Wild Card | vs | W 26-19 | 2 | 18 | 308 | 385 | 41.7 | 100.0 | ||
| 6 | | Chiefs | 6 | 1/23/2022 | AFC Divisional | vs | W 42-36 | 5 | 30 | 552 | 422 | 61.5 | 100.0 | ||
| 7 |  | 49ers | 6 | 1/16/2022 | NFC Wild Card | @ | W 23-17 | 2 | 21 | 341 | 307 | 46.2 | |||
| 8 | | Rams | 3 | 2/13/2022 | Super Bowl | @ | W 23-20 | 3 | 18 | 313 | 305 | 40.0 | 100.0 | ||
| 9 | | Bengals | 3 | 1/30/2022 | AFC Championship | @ | W 27-24 | 2 | 21 | 359 | 375 | 57.1 | |||
| 10 | | Rams | 3 | 1/30/2022 | NFC Championship | vs | W 20-17 | 2 | 25 | 396 | 282 | 61.1 | 0.0 | ||
| 11 | | Rams | 3 | 1/23/2022 | NFC Divisional | @ | W 30-27 | 3 | 24 | 428 | 359 | 36.4 | |||
| 12 | | Bengals | 3 | 1/22/2022 | AFC Divisional | @ | W 19-16 | 1 | 17 | 345 | 353 | 46.7 | |||
| 13 | | 49ers | 3 | 1/22/2022 | NFC Divisional | @ | W 13-10 | 1 | 12 | 212 | 263 | 36.4 | 0.0 | ||
| 14 | | Bengals | -3 | 2/13/2022 | Super Bowl | vs | L 20-23 | 2 | 15 | 305 | 313 | 21.4 | 33.3 | ||
| 15 | | Chiefs | -3 | 1/30/2022 | AFC Championship | vs | L 24-27 | 3 | 24 | 375 | 359 | 50.0 | |||
| 16 | | 49ers | -3 | 1/30/2022 | NFC Championship | @ | L 17-20 | 2 | 16 | 282 | 396 | 33.3 | |||
| 17 | | Buccaneers | -3 | 1/23/2022 | NFC Divisional | vs | L 27-30 | 3 | 20 | 359 | 428 | 21.4 | 50.0 | ||
| 18 |  | Titans | -3 | 1/22/2022 | AFC Divisional | vs | L 16-19 | 2 | 16 | 353 | 345 | 12.5 | 0.0 | ||
| 19 |  | Packers | -3 | 1/22/2022 | NFC Divisional | vs | L 10-13 | 1 | 14 | 263 | 212 | 41.7 | |||
| 20 | | Bills | -6 | 1/23/2022 | AFC Divisional | @ | L 36-42 | 5 | 23 | 422 | 552 | 42.9 | 100.0 | ||
| 21 |  | Cowboys | -6 | 1/16/2022 | NFC Wild Card | vs | L 17-23 | 2 | 20 | 307 | 341 | 35.7 | 50.0 | ||
| 22 |  | Raiders | -7 | 1/15/2022 | AFC Wild Card | @ | L 19-26 | 1 | 23 | 385 | 308 | 44.4 | 50.0 | ||
| 23 |  | Eagles | -16 | 1/16/2022 | NFC Wild Card | @ | L 15-31 | 2 | 14 | 339 | 349 | 35.7 | 33.3 | ||
| 24 |  | Steelers | -21 | 1/16/2022 | AFC Wild Card | @ | L 21-42 | 3 | 19 | 257 | 478 | 43.8 | 100.0 | ||
| 25 |  | Cardinals | -23 | 1/17/2022 | NFC Wild Card | @ | L 11-34 | 1 | 14 | 183 | 375 | 0.0 | 50.0 | ||
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More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |