Between January 15, 2001 and January 15, 2021, Nick Chubb has the most rushing yards per attempt when playing 12+ games and averaging 70.0+ rushing yards per game, with 5.2 per attempt.

highest rush yards per carry in the last 20 years with a minimum 12 games played and 70 rush yards per game
Interpreted as:
highest rush yards by a player per carry in the last 20 years with a minimum 12 games played and 70 or higher rush yards per game

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