James Cook III has had 110 carries for 497 yards and has scored 7 touchdowns in 8 games against the Patriots in his career.
| NAME | DATE | TM | OPP | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Cook III | 12/1/2022 | @ | 64 | 14 | 4.6 | 0 | 41 | 6 | 6 | 6.8 | 0 | ||
| 2 | | J. Cook III | 1/8/2023 | vs | 45 | 9 | 5.0 | 0 | 6 | 2 | 2 | 3.0 | 0 | ||
| 3 | | J. Cook III | 10/22/2023 | @ | 56 | 13 | 4.3 | 0 | 46 | 3 | 3 | 15.3 | 1 | ||
| 4 | | J. Cook III | 12/31/2023 | vs | 48 | 16 | 3.0 | 0 | -4 | 1 | 3 | -4.0 | 0 | ||
| 5 | | J. Cook III | 12/22/2024 | vs | 100 | 11 | 9.1 | 1 | 26 | 3 | 3 | 8.7 | 1 | ||
| 6 | | J. Cook III | 1/5/2025 | @ | 28 | 10 | 2.8 | 1 | 0 | 0 | 0 | 0 | |||
| 7 | | J. Cook III | 10/5/2025 | vs | 49 | 15 | 3.3 | 0 | 0 | 0 | 1 | 0 | |||
| 8 | | J. Cook III | 12/14/2025 | @ | 107 | 22 | 4.9 | 2 | 4 | 2 | 3 | 2.0 | 1 | ||
| Average | 62.1 | 13.8 | 4.5 | 0.5 | 14.9 | 2.1 | 2.6 | 7.0 | 0.4 | ||||||
| Total | 497 | 110 | 4.5 | 4 | 119 | 17 | 21 | 7.0 | 3 |
More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
