The Buffalo Bills had the highest point differential by a team in 2021, with a 243-point differential.
| TEAM | DIFF | SEASON | GP | W | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 243 | 2021 | 11 | 11 | 0 | 0 | 47 | 378 | 34.4 | 135 | 12.3 | 269 | 50.7 | 61.5 |
| 2 |  | Patriots | 214 | 2021 | 10 | 10 | 0 | 0 | 35 | 325 | 32.5 | 111 | 11.1 | 224 | 46.3 | 60.0 |
| 3 |  | Cowboys | 204 | 2021 | 12 | 12 | 0 | 0 | 52 | 421 | 35.1 | 217 | 18.1 | 289 | 46.5 | 64.7 |
| 4 |  | Buccaneers | 196 | 2021 | 13 | 13 | 0 | 0 | 54 | 441 | 33.9 | 245 | 18.8 | 330 | 48.2 | 60.0 |
| 5 |  | Chiefs | 168 | 2021 | 12 | 12 | 0 | 0 | 43 | 367 | 30.6 | 199 | 16.6 | 290 | 54.8 | 70.0 |
| 6 |  | Cardinals | 149 | 2021 | 11 | 11 | 0 | 0 | 40 | 337 | 30.6 | 188 | 17.1 | 249 | 45.3 | 83.3 |
| 7 |  | Rams | 149 | 2021 | 12 | 12 | 0 | 0 | 42 | 362 | 30.2 | 213 | 17.8 | 259 | 45.3 | 63.6 |
| 8 |  | Eagles | 148 | 2021 | 9 | 9 | 0 | 0 | 30 | 281 | 31.2 | 133 | 14.8 | 193 | 45.5 | 40.0 |
| 9 |  | Bengals | 145 | 2021 | 10 | 10 | 0 | 0 | 36 | 313 | 31.3 | 168 | 16.8 | 208 | 40.8 | 81.8 |
| 10 |  | Colts | 144 | 2021 | 9 | 9 | 0 | 0 | 33 | 277 | 30.8 | 133 | 14.8 | 184 | 43.0 | 72.7 |
| 11 |  | Titans | 131 | 2021 | 12 | 12 | 0 | 0 | 40 | 343 | 28.6 | 212 | 17.7 | 249 | 46.5 | 88.9 |
| 12 |  | Packers | 130 | 2021 | 13 | 13 | 0 | 0 | 45 | 379 | 29.2 | 249 | 19.2 | 299 | 45.2 | 57.1 |
| 13 |  | Saints | 121 | 2021 | 9 | 9 | 0 | 0 | 26 | 235 | 26.1 | 114 | 12.7 | 175 | 36.4 | 80.0 |
| 14 |  | 49ers | 114 | 2021 | 10 | 10 | 0 | 0 | 33 | 293 | 29.3 | 179 | 17.9 | 219 | 46.0 | 57.1 |
| 15 |  | Broncos | 114 | 2021 | 7 | 7 | 0 | 0 | 21 | 189 | 27.0 | 75 | 10.7 | 157 | 50.0 | 100.0 |
| 16 |  | Seahawks | 100 | 2021 | 7 | 7 | 0 | 0 | 31 | 239 | 34.1 | 139 | 19.9 | 138 | 44.4 | 100.0 |
| 17 |  | Dolphins | 95 | 2021 | 9 | 9 | 0 | 0 | 25 | 217 | 24.1 | 122 | 13.6 | 178 | 42.4 | 66.7 |
| 18 |  | Chargers | 92 | 2021 | 9 | 9 | 0 | 0 | 38 | 305 | 33.9 | 213 | 23.7 | 226 | 50.4 | 71.4 |
| 19 |  | Browns | 75 | 2021 | 8 | 8 | 0 | 0 | 22 | 187 | 23.4 | 112 | 14.0 | 171 | 45.3 | 33.3 |
| 20 |  | Panthers | 69 | 2021 | 5 | 5 | 0 | 0 | 12 | 122 | 24.4 | 53 | 10.6 | 119 | 47.2 | 0.0 |
| 21 |  | Ravens | 65 | 2021 | 8 | 8 | 0 | 0 | 22 | 209 | 26.1 | 144 | 18.0 | 204 | 41.7 | 100.0 |
| 22 |  | Vikings | 61 | 2021 | 8 | 8 | 0 | 0 | 25 | 228 | 28.5 | 167 | 20.9 | 167 | 45.6 | 75.0 |
| 23 |  | Raiders | 54 | 2021 | 10 | 10 | 0 | 0 | 28 | 284 | 28.4 | 230 | 23.0 | 227 | 42.4 | 77.8 |
| 24 |  | Bears | 53 | 2021 | 6 | 6 | 0 | 0 | 14 | 134 | 22.3 | 81 | 13.5 | 119 | 39.2 | 50.0 |
| 25 |  | Texans | 51 | 2021 | 4 | 4 | 0 | 0 | 14 | 130 | 32.5 | 79 | 19.8 | 76 | 53.6 | 100.0 |
More Bills Stats
Team Leaders 
PASS
273
Allen
RUSH
46
Cook
REC
82
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
