| TEAM | OPPONENT | WEEK/ROUND | DATE | TIME (ET) | SPREAD | OVER/UNDER | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Buffalo Bills | -113 | @ | -106 | WK 1 | Sun, Sep 13, 2026 | 1:00 PM | -1.5 | 44.5 | |
| 2 | | Buffalo Bills | -161 | vs | +136 | WK 2 | Thu, Sep 17, 2026 | 8:15 PM | -3.0 | 52.5 | |
| 3 | | Buffalo Bills | -159 | vs | +130 | WK 3 | Sun, Sep 27, 2026 | 1:00 PM | -2.5 | 48.5 | |
| 4 | | Buffalo Bills | -179 | vs | +148 | WK 4 | Sun, Oct 4, 2026 | 1:00 PM | -3.0 | 49.5 | |
| 5 | | Buffalo Bills | +167 | @ | -205 | WK 5 | Mon, Oct 12, 2026 | 8:15 PM | +3.5 | 53.5 | |
| 6 | | Buffalo Bills | -154 | vs | +130 | WK 12 | Thu, Nov 26, 2026 | 8:20 PM | -2.5 | 49.5 | |
| 7 | | Buffalo Bills | -126 | @ | +106 | WK 16 | Fri, Dec 25, 2026 | 4:30 PM | -1.5 | 46.5 |
Betting lines shown represent consensus, closing odds.
More NFL News
Khosla family agrees to purchase defending Super Bowl champion Seattle for $9.612B, AP source says
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Washington Commanders are retiring Hall of Famer John Riggins' No. 44 on Nov. 8
Adam Vinatieri will celebrate on the field in Indianapolis again as Colts' Ring of Honor member
Former Dallas Cowboys defensive end Kneeland had early stage CTE at time of death
Cornerback Rasul Douglas agrees to a 1-year contract with the Commanders, AP source says
More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |