Interpreted as:
most 100 or more yard rushing regular-season games in NFL history by a bills player| NAME | GP | RUSH YDS | ATT | YPC | RUSH YDS/G | RUSH TD | REC YDS | REC | TRG | AVG | REC YDS/G | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | T. Thomas | 46 | 5,666 | 1,112 | 5.1 | 123.2 | 32 | 1,205 | 121 | 10.0 | 26.2 | 10 | |
| 2 |  | O.J. Simpson | 41 | 6,140 | 1,038 | 5.9 | 149.8 | 35 | 443 | 45 | 9.8 | 10.8 | 4 | |
| 3 |  | L. McCoy | 15 | 1,894 | 309 | 6.1 | 126.3 | 16 | 283 | 43 | 49 | 6.6 | 18.9 | 1 |
| 4 | | F. Jackson | 15 | 1,896 | 337 | 5.6 | 126.4 | 8 | 351 | 45 | 59 | 7.8 | 23.4 | 2 |
| 5 | | W. McGahee | 14 | 1,692 | 356 | 4.8 | 120.9 | 14 | 215 | 26 | 42 | 8.3 | 15.4 | 0 |
| 6 | | T. Henry | 13 | 1,797 | 342 | 5.3 | 138.2 | 13 | 200 | 24 | 39 | 8.3 | 15.4 | 0 |
| 7 | | J. Cribbs | 13 | 1,702 | 304 | 5.6 | 130.9 | 5 | 323 | 33 | 9.8 | 24.8 | 2 | |
| 8 |  | J. Cook III | 10 | 1,191 | 172 | 6.9 | 119.1 | 11 | 209 | 23 | 25 | 9.1 | 20.9 | 2 |
| 9 | | C.J. Spiller | 10 | 1,224 | 160 | 7.7 | 122.4 | 6 | 217 | 27 | 38 | 8.0 | 21.7 | 0 |
| 10 | | C. Gilchrist | 10 | 1,372 | 226 | 6.1 | 137.2 | 15 | 122 | 12 | 10.2 | 12.2 | 3 | |
| 11 | | A. Smith | 7 | 870 | 164 | 5.3 | 124.3 | 11 | 36 | 4 | 1 | 9.0 | 5.1 | 0 |
| 12 |  | M. Lynch | 6 | 745 | 134 | 5.6 | 124.2 | 1 | 101 | 16 | 25 | 6.3 | 16.8 | 1 |
| 13 | | G. Bell | 4 | 586 | 103 | 5.7 | 146.5 | 2 | 90 | 10 | 9.0 | 22.5 | 1 | |
| 14 | | J. Braxton | 4 | 482 | 91 | 5.3 | 120.5 | 7 | 75 | 6 | 12.5 | 18.8 | 1 | |
| 15 |  | D. Singletary | 3 | 322 | 56 | 5.8 | 107.3 | 3 | 27 | 3 | 6 | 9.0 | 9.0 | 0 |
| 16 |  | J. Allen | 3 | 345 | 30 | 11.5 | 115.0 | 2 | 0 | 0 | 1 | 0.0 | 0 | |
| 17 | | K. Davis | 3 | 407 | 54 | 7.5 | 135.7 | 3 | 35 | 6 | 5.8 | 11.7 | 0 | |
| 18 | | R. Riddick | 3 | 329 | 70 | 4.7 | 109.7 | 1 | 48 | 6 | 8.0 | 16.0 | 0 | |
| 19 | | R. Hooks | 3 | 379 | 58 | 6.5 | 126.3 | 3 | 0 | 0 | 0.0 | 0 | ||
| 20 | | K. Williams | 2 | 220 | 21 | 10.5 | 110.0 | 3 | 0 | 0 | 0 | 0.0 | 0 | |
| 21 | | S. Bryson | 2 | 237 | 44 | 5.4 | 118.5 | 2 | 31 | 3 | 5 | 10.3 | 15.5 | 0 |
| 22 | | D. Holmes | 2 | 222 | 45 | 4.9 | 111.0 | 3 | 18 | 2 | 9.0 | 9.0 | 0 | |
| 23 | | T. Miller | 2 | 331 | 36 | 9.2 | 165.5 | 3 | 7 | 2 | 3.5 | 3.5 | 0 | |
| 24 | | C. Brown | 2 | 214 | 29 | 7.4 | 107.0 | 1 | 20 | 6 | 3.3 | 10.0 | 0 | |
| 25 |  | F. Gore | 1 | 109 | 17 | 6.4 | 109.0 | 0 | 0 | 0 | 1 | 0.0 | 0 | |
StatMuse has game-level data for rushing yards going back to the 1960 season.
More Bills Stats
Team Rankings
PPG
33.3
2nd
OPP PPG
22.5
17th
RUSH YDS/G
163.5
1st
PASS YDS/G
249.0
7th
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NFL 2025 Division Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles | 4 | 0 | 0 | 1.000 |
 Commanders | 2 | 2 | 0 | .500 |
| NFC North | W | L | T | PCT |
 Lions | 3 | 1 | 0 | .750 |
 Packers | 2 | 1 | 1 | .625 |
| NFC South | W | L | T | PCT |
 Buccaneers | 3 | 1 | 0 | .750 |
 Falcons | 2 | 2 | 0 | .500 |
| NFC West | W | L | T | PCT |
 49ers | 3 | 1 | 0 | .750 |
 Seahawks | 3 | 1 | 0 | .750 |
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