21 teams are tied for the highest point differential in a loss, with a -1-point differential. The first three are the Buffalo Bills on December 28, the Los Angeles Rams on December 18 and the Tampa Bay Buccaneers on December 11.
Interpreted as:
most difference total yardage differential in a regular-season loss ever| TEAM | DIFF | YDS | L | DATE | TM | OPP | RESULT | TD | PASS YDS | SCKY | PASS TD | RUSH YDS | RUSH TD | RET YDS | RET TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | -1 | 331 | 1 | 12/28/2025 | vs | L 12-13 | 2 | 262 | 51 | 0 | 120 | 2 | 134 | 0 | ||
| 2 |  | Rams | -1 | 581 | 1 | 12/18/2025 | @ | L 37-38 | 4 | 457 | 0 | 3 | 124 | 1 | 158 | 0 | ||
| 3 |  | Buccaneers | -1 | 338 | 1 | 12/11/2025 | vs | L 28-29 | 3 | 277 | 27 | 2 | 88 | 1 | 72 | 0 | ||
| 4 |  | Commanders | -1 | 419 | 1 | 11/30/2025 | vs | L 26-27 | 3 | 294 | 18 | 2 | 143 | 1 | 129 | 0 | ||
| 5 |  | Falcons | -1 | 288 | 1 | 11/2/2025 | @ | L 23-24 | 3 | 221 | 4 | 3 | 71 | 0 | 148 | 0 | ||
| 6 |  | Raiders | -1 | 331 | 1 | 11/2/2025 | vs | L 29-30 | 4 | 284 | 10 | 4 | 57 | 0 | 232 | 0 | ||
| 7 |  | Bengals | -1 | 398 | 1 | 10/26/2025 | vs | L 38-39 | 5 | 223 | 6 | 2 | 181 | 3 | 114 | 0 | ||
| 8 |  | Giants | -1 | 387 | 1 | 10/19/2025 | @ | L 32-33 | 5 | 283 | 15 | 3 | 119 | 2 | 113 | 0 | ||
| 9 | | Commanders | -1 | 329 | 1 | 10/13/2025 | vs | L 24-25 | 3 | 211 | 6 | 3 | 124 | 0 | 136 | 0 | ||
| 10 |  | Cardinals | -1 | 360 | 1 | 10/5/2025 | vs | L 21-22 | 3 | 220 | 28 | 0 | 168 | 3 | 106 | 0 | ||
| 11 | | Raiders | -1 | 357 | 1 | 9/28/2025 | vs | L 24-25 | 3 | 117 | 0 | 2 | 240 | 1 | 197 | 0 | ||
| 12 | | Cardinals | -1 | 260 | 1 | 9/21/2025 | @ | L 15-16 | 1 | 159 | 5 | 1 | 106 | 0 | 123 | 0 | ||
| 13 |  | Texans | -1 | 266 | 1 | 9/15/2025 | vs | L 19-20 | 2 | 207 | 25 | 1 | 84 | 1 | 174 | 0 | ||
| 14 |  | Broncos | -1 | 324 | 1 | 9/14/2025 | @ | L 28-29 | 4 | 206 | 0 | 3 | 118 | 1 | 122 | 0 | ||
| 15 |  | Browns | -1 | 327 | 1 | 9/7/2025 | vs | L 16-17 | 2 | 290 | 12 | 1 | 49 | 1 | 146 | 0 | ||
| 16 |  | Ravens | -1 | 432 | 1 | 9/7/2025 | @ | L 40-41 | 5 | 209 | 15 | 2 | 238 | 3 | 173 | 0 | ||
| 17 |  | Saints | -1 | 245 | 1 | 12/15/2024 | vs | L 19-20 | 2 | 205 | 29 | 2 | 69 | 0 | 146 | 0 | ||
| 18 |  | Patriots | -1 | 422 | 1 | 12/1/2024 | vs | L 24-25 | 2 | 238 | 16 | 1 | 200 | 1 | 111 | 0 | ||
| 19 | | Cardinals | -1 | 406 | 1 | 12/1/2024 | @ | L 22-23 | 1 | 260 | 8 | 1 | 154 | 0 | 36 | 0 | ||
| 20 |  | Bears | -1 | 391 | 1 | 11/17/2024 | vs | L 19-20 | 2 | 231 | 19 | 0 | 179 | 2 | 55 | 0 | ||
| 21 |  | Jets | -1 | 253 | 1 | 11/17/2024 | vs | L 27-28 | 3 | 184 | 22 | 2 | 91 | 1 | 43 | 0 | ||
| 22 | | Commanders | -1 | 242 | 1 | 11/10/2024 | vs | L 27-28 | 3 | 202 | 20 | 0 | 60 | 3 | 118 | 0 | ||
| 23 | | Bengals | -1 | 470 | 1 | 11/7/2024 | @ | L 34-35 | 5 | 428 | 7 | 4 | 49 | 1 | 13 | 0 | ||
| 24 | | Saints | -1 | 427 | 1 | 11/3/2024 | @ | L 22-23 | 2 | 236 | 6 | 1 | 197 | 1 | 66 | 0 | ||
| 25 |  | Dolphins | -1 | 377 | 1 | 10/27/2024 | vs | L 27-28 | 3 | 234 | 7 | 1 | 150 | 2 | 60 | 0 | ||
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More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |