The Buffalo Bills had the highest point differential per game played by a team in the 2021 regular-season and playoffs, with 11.47 in 2021.
| TEAM | DIFF/GP | DIFF | GP | SEASON | W | L | T | TD | PTS | PPG | OPP PTS | OPP PPG | 1DWN | 3DWN% | 4DWN% | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | Bills | 11.47 | 218 | 19 | 2021 | 12 | 7 | 0 | 69 | 566 | 29.8 | 348 | 18.3 | 450 | 47.3 | 57.7 |
| 2 |  | Cowboys | 9.22 | 166 | 18 | 2021 | 12 | 6 | 0 | 66 | 547 | 30.4 | 381 | 21.2 | 410 | 43.0 | 57.7 |
| 3 |  | Buccaneers | 9 | 171 | 19 | 2021 | 14 | 5 | 0 | 70 | 569 | 29.9 | 398 | 20.9 | 447 | 44.8 | 52.4 |
| 4 |  | Patriots | 7.17 | 129 | 18 | 2021 | 10 | 8 | 0 | 53 | 479 | 26.6 | 350 | 19.4 | 382 | 43.9 | 71.4 |
| 5 |  | Chiefs | 7 | 140 | 20 | 2021 | 14 | 6 | 0 | 71 | 588 | 29.4 | 448 | 22.4 | 499 | 53.3 | 68.8 |
| 6 |  | Rams | 5.71 | 120 | 21 | 2021 | 16 | 5 | 0 | 64 | 567 | 27.0 | 447 | 21.3 | 438 | 44.7 | 52.4 |
| 7 |  | Colts | 5.06 | 86 | 17 | 2021 | 9 | 8 | 0 | 52 | 451 | 26.5 | 365 | 21.5 | 354 | 41.0 | 62.1 |
| 8 |  | Bengals | 4.48 | 94 | 21 | 2021 | 13 | 8 | 0 | 61 | 552 | 26.3 | 458 | 21.8 | 408 | 40.1 | 62.5 |
| 9 |  | Packers | 4.22 | 76 | 18 | 2021 | 13 | 5 | 0 | 55 | 460 | 25.6 | 384 | 21.3 | 389 | 43.5 | 59.1 |
| 10 |  | Titans | 3.44 | 62 | 18 | 2021 | 12 | 6 | 0 | 51 | 435 | 24.2 | 373 | 20.7 | 379 | 42.6 | 60.0 |
| 11 |  | 49ers | 3.4 | 68 | 20 | 2021 | 12 | 8 | 0 | 55 | 480 | 24.0 | 412 | 20.6 | 410 | 40.1 | 47.6 |
| 12 |  | Cardinals | 3.33 | 60 | 18 | 2021 | 11 | 7 | 0 | 53 | 460 | 25.6 | 400 | 22.2 | 381 | 43.5 | 58.1 |
| 13 |  | Eagles | 2.39 | 43 | 18 | 2021 | 9 | 9 | 0 | 52 | 459 | 25.5 | 416 | 23.1 | 366 | 45.1 | 44.4 |
| 14 |  | Saints | 1.71 | 29 | 17 | 2021 | 9 | 8 | 0 | 43 | 364 | 21.4 | 335 | 19.7 | 307 | 35.5 | 52.4 |
| 15 |  | Seahawks | 1.71 | 29 | 17 | 2021 | 7 | 10 | 0 | 49 | 395 | 23.2 | 366 | 21.5 | 302 | 37.3 | 36.4 |
| 16 |  | Chargers | 0.88 | 15 | 17 | 2021 | 9 | 8 | 0 | 58 | 474 | 27.9 | 459 | 27.0 | 401 | 45.2 | 64.7 |
| 17 |  | Broncos | 0.76 | 13 | 17 | 2021 | 7 | 10 | 0 | 37 | 335 | 19.7 | 322 | 18.9 | 331 | 38.5 | 57.1 |
| 18 |  | Vikings | -0.06 | -1 | 17 | 2021 | 8 | 9 | 0 | 48 | 425 | 25.0 | 426 | 25.1 | 332 | 36.4 | 54.5 |
| 19 |  | Ravens | -0.29 | -5 | 17 | 2021 | 8 | 9 | 0 | 41 | 387 | 22.8 | 392 | 23.1 | 394 | 36.4 | 66.7 |
| 20 |  | Browns | -1.29 | -22 | 17 | 2021 | 8 | 9 | 0 | 43 | 349 | 20.5 | 371 | 21.8 | 342 | 39.2 | 41.4 |
| 21 |  | Dolphins | -1.88 | -32 | 17 | 2021 | 9 | 8 | 0 | 39 | 341 | 20.1 | 373 | 21.9 | 325 | 40.8 | 54.5 |
| 22 |  | Raiders | -4 | -72 | 18 | 2021 | 10 | 8 | 0 | 38 | 393 | 21.8 | 465 | 25.8 | 372 | 37.9 | 61.9 |
| 23 |  | Steelers | -4.22 | -76 | 18 | 2021 | 9 | 8 | 1 | 37 | 364 | 20.2 | 440 | 24.4 | 343 | 39.2 | 52.2 |
| 24 |  | Bears | -5.65 | -96 | 17 | 2021 | 6 | 11 | 0 | 33 | 311 | 18.3 | 407 | 23.9 | 333 | 34.7 | 41.7 |
| 25 |  | Washington Football Team | -5.82 | -99 | 17 | 2021 | 7 | 10 | 0 | 37 | 335 | 19.7 | 434 | 25.5 | 345 | 38.8 | 50.0 |
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More Bills Stats
Team Leaders 
PASS
3,668
Allen
RUSH
1,621
Cook
REC
719
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |