Between the 2018 and 2021 seasons, Derrick Henry had the most rushing yards, with 5,563 yards.

Interpreted as:

most rush yards by a player between 2018 to 2021

	NAME	RUSH YDS	GP	ATT	YPC	RUSH YDS/G	RUSH TD	REC YDS	REC	TRG	AVG	REC YDS/G	REC TD
1	Derrick Henry D. Henry	5,563	55	1,115	5.0	101.1	55	573	70	93	8.2	10.4	2
2	Nick Chubb N. Chubb	4,816	58	908	5.3	83.0	36	751	92	121	8.2	12.9	3
3	Ezekiel Elliott E. Elliott	4,772	63	1,086	4.4	75.7	34	1,612	230	302	7.0	25.6	9
4	Dalvin Cook D. Cook	4,466	52	944	4.7	85.9	37	1,409	171	215	8.2	27.1	3
5	Joe Mixon J. Mixon	3,938	52	926	4.3	75.7	29	1,035	141	174	7.3	19.9	8
6	Aaron Jones Sr. A. Jones Sr.	3,715	57	741	5.0	65.2	37	1,426	174	231	8.2	25.0	12
7	Lamar Jackson L. Jackson	3,673	58	615	6.0	63.3	21	0	0	2		0.0	0
8	Alvin Kamara A. Kamara	3,510	57	792	4.4	61.6	39	2,437	292	376	8.3	42.8	15
9	Melvin Gordon M. Gordon	3,401	55	755	4.5	61.8	35	1,157	152	203	7.6	21.0	8
10	Chris Carson C. Carson	3,294	45	720	4.6	73.2	24	745	100	123	7.5	16.6	6
11	Christian McCaffrey C. McCaffrey	3,152	42	664	4.7	75.0	28	2,364	277	326	8.5	56.3	12
12	Sony Michel S. Michel	3,137	55	743	4.2	57.0	18	386	47	73	8.2	7.0	2
13	Josh Jacobs J. Jacobs	3,087	43	732	4.2	71.8	28	752	107	136	7.0	17.5	0
14	Jonathan Taylor J. Taylor	2,980	32	564	5.3	93.1	29	659	76	90	8.7	20.6	3
15	Saquon Barkley S. Barkley	2,937	44	659	4.5	66.8	19	1,482	190	260	7.8	33.7	8
16	James Conner J. Conner	2,907	51	702	4.1	57.0	37	1,338	161	191	8.3	26.2	7
17	David Montgomery D. Montgomery	2,808	44	714	3.9	63.8	21	924	121	154	7.6	21.0	3
18	Phillip Lindsay P. Lindsay	2,799	56	622	4.5	50.0	18	510	81	114	6.3	9.1	2
19	Todd Gurley T. Gurley	2,786	44	674	4.1	63.3	38	951	115	165	8.3	21.6	6
20	Leonard Fournette L. Fournette	2,770	50	675	4.1	55.4	22	1,394	203	257	6.9	27.9	3
21	Adrian Peterson A. Peterson	2,642	51	656	4.0	51.8	21	459	53	71	8.7	9.0	1
22	Kenyan Drake K. Drake	2,561	57	592	4.3	44.9	24	1,250	158	212	7.9	21.9	6
23	Austin Ekeler A. Ekeler	2,552	56	560	4.6	45.6	19	2,447	255	320	9.6	43.7	21
24	Mark Ingram M. Ingram	2,516	52	572	4.4	48.4	20	629	80	99	7.9	12.1	6
25	Miles Sanders M. Sanders	2,439	40	480	5.1	61.0	9	864	104	149	8.3	21.6	3

Unlock 2x data

StatMuse has season-level data for rushing yards going back to the 1932 season.

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NFL 2025 Standings

AFC East	W	L	T	PCT
Patriots - y	14	3	0	.824
Bills - w	12	5	0	.706
Dolphins - e	7	10	0	.412
Jets - e	3	14	0	.176
AFC North	W	L	T	PCT
Steelers - y	10	7	0	.588
Ravens - e	8	9	0	.471
Bengals - e	6	11	0	.353
Browns - e	5	12	0	.294
AFC South	W	L	T	PCT
Jaguars - y	13	4	0	.765
Texans - w	12	5	0	.706
Colts - e	8	9	0	.471
Titans - e	3	14	0	.176
AFC West	W	L	T	PCT
Broncos - z*	14	3	0	.824
Chargers - w	11	6	0	.647
Chiefs - e	6	11	0	.353
Raiders - e	3	14	0	.176

NFC East	W	L	T	PCT
Eagles - y	11	6	0	.647
Cowboys - e	7	9	1	.441
Commanders - e	5	12	0	.294
Giants - e	4	13	0	.235
NFC North	W	L	T	PCT
Bears - y	11	6	0	.647
Packers - w	9	7	1	.559
Vikings - e	9	8	0	.529
Lions - e	9	8	0	.529
NFC South	W	L	T	PCT
Panthers - y	8	9	0	.471
Buccaneers - e	8	9	0	.471
Falcons - e	8	9	0	.471
Saints - e	6	11	0	.353
NFC West	W	L	T	PCT
Seahawks - z*	14	3	0	.824
Rams - w	12	5	0	.706
49ers - w	12	5	0	.706
Cardinals - e	3	14	0	.176