Edgerrin James had the most rushing touchdowns by a Colts running back in a 2005 regular-season or postseason game, with 3 touchdowns against the St. Louis Rams on October 17, 2005.
| NAME | RUSH TD | DATE | TM | OPP | RUSH YDS | ATT | YPC | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | E. James | 3 | 10/17/2005 | vs | 143 | 23 | 6.2 | 16 | 3 | 4 | 5.3 | 0 | ||
| 2 | | E. James | 2 | 11/20/2005 | @ | 89 | 24 | 3.7 | 18 | 3 | 3 | 6.0 | 0 | ||
| 3 | | E. James | 2 | 10/23/2005 | @ | 139 | 21 | 6.6 | 8 | 1 | 1 | 8.0 | 0 | ||
| 4 | | E. James | 1 | 1/15/2006 | vs | 56 | 13 | 4.3 | 26 | 5 | 6 | 5.2 | 0 | ||
| 5 | | E. James | 1 | 12/18/2005 | vs | 25 | 13 | 1.9 | 20 | 2 | 2 | 10.0 | 0 | ||
| 6 | | E. James | 1 | 12/4/2005 | vs | 107 | 28 | 3.8 | 17 | 2 | 3 | 8.5 | 0 | ||
| 7 |  | D. Rhodes | 1 | 11/20/2005 | @ | 6 | 2 | 3.0 | 0 | 0 | 0 | 0 | |||
| 8 | | E. James | 1 | 11/13/2005 | vs | 122 | 26 | 4.7 | 26 | 3 | 4 | 8.7 | 0 | ||
| 9 | | E. James | 1 | 11/7/2005 | @ | 104 | 34 | 3.1 | 9 | 3 | 3 | 3.0 | 0 | ||
| 10 | | D. Rhodes | 1 | 11/7/2005 | @ | 4 | 1 | 4.0 | 0 | 0 | 0 | 0 | |||
| 11 | | D. Rhodes | 1 | 10/17/2005 | vs | 29 | 11 | 2.6 | 8 | 1 | 2 | 8.0 | 0 | ||
| 12 | | E. James | 1 | 10/9/2005 | @ | 105 | 21 | 5.0 | 42 | 4 | 5 | 10.5 | 0 | ||
| 13 | | D. Rhodes | 1 | 10/9/2005 | @ | 18 | 5 | 3.6 | 8 | 1 | 1 | 8.0 | 0 | ||
| 14 | | E. James | 1 | 9/25/2005 | vs | 108 | 27 | 4.0 | 29 | 2 | 2 | 14.5 | 0 | ||
| 15 | | R. Carthon | 1 | 9/18/2005 | vs | 5 | 6 | 0.8 | 0 | 0 | 0 | 0 |
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More Colts Stats
Team Leaders 
PASS
3,101
Jones
RUSH
1,585
Taylor
REC
1,003
Pierce
Team Rankings
PPG
27.4
8th
OPP PPG
24.2
21st
RUSH YDS/G
118.1
17th
PASS YDS/G
240.3
8th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |