O.J. Simpson has averaged the most rushing yards per game by a Bills running back in a season, with 143.1 per game in 1973.
| NAME | RUSH YDS/G | SEASON | TM | GP | RUSH YDS | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC YDS/G | REC TD | ||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | O.J. Simpson | 143.1 | 1973 |  BUF | 14 | 2,003 | 332 | 6.0 | 12 | 70 | 6 | 11.7 | 5.0 | 0 | |
| 2 | | O.J. Simpson | 129.8 | 1975 | BUF | 14 | 1,817 | 329 | 5.5 | 16 | 426 | 28 | 15.2 | 30.4 | 7 | |
| 3 | | O.J. Simpson | 107.4 | 1976 | BUF | 14 | 1,503 | 290 | 5.2 | 8 | 259 | 22 | 11.8 | 18.5 | 1 | |
| 4 |  | J. Cook III | 98.5 | 2025 | BUF | 11 | 1,084 | 199 | 5.4 | 8 | 203 | 24 | 26 | 8.5 | 18.5 | 1 |
| 5 |  | T. Thomas | 93.8 | 1991 | BUF | 15 | 1,407 | 288 | 4.9 | 7 | 631 | 62 | 10.2 | 42.1 | 5 | |
| 6 | | F. Jackson | 93.4 | 2011 | BUF | 10 | 934 | 170 | 5.5 | 6 | 442 | 39 | 50 | 11.3 | 44.2 | 0 |
| 7 | | T. Thomas | 92.9 | 1992 | BUF | 16 | 1,487 | 312 | 4.8 | 9 | 626 | 58 | 10.8 | 39.1 | 3 | |
| 8 | | J. Cribbs | 90.4 | 1982 | BUF | 7 | 633 | 134 | 4.7 | 3 | 99 | 13 | 7.6 | 14.1 | 0 | |
| 9 | | T. Henry | 90.4 | 2003 | BUF | 15 | 1,356 | 331 | 4.1 | 10 | 158 | 28 | 40 | 5.6 | 10.5 | 1 |
| 10 | | T. Henry | 89.9 | 2002 | BUF | 16 | 1,438 | 325 | 4.4 | 13 | 309 | 43 | 59 | 7.2 | 19.3 | 1 |
| 11 | | O.J. Simpson | 89.4 | 1972 | BUF | 14 | 1,251 | 292 | 4.3 | 6 | 198 | 27 | 7.3 | 14.1 | 0 | |
| 12 |  | M. Lynch | 85.8 | 2007 | BUF | 13 | 1,115 | 280 | 4.0 | 7 | 184 | 18 | 26 | 10.2 | 14.2 | 0 |
| 13 |  | L. McCoy | 84.5 | 2016 | BUF | 15 | 1,267 | 234 | 5.4 | 13 | 356 | 50 | 57 | 7.1 | 23.7 | 1 |
| 14 | | J. Braxton | 82.3 | 1973 | BUF | 6 | 494 | 108 | 4.6 | 4 | 101 | 6 | 16.8 | 16.8 | 0 | |
| 15 | | T. Thomas | 82.2 | 1993 | BUF | 16 | 1,315 | 355 | 3.7 | 6 | 387 | 48 | 8.1 | 24.2 | 0 | |
| 16 | | T. Thomas | 81.1 | 1990 | BUF | 16 | 1,297 | 271 | 4.8 | 11 | 532 | 49 | 10.9 | 33.3 | 2 | |
| 17 | | O.J. Simpson | 80.4 | 1974 | BUF | 14 | 1,125 | 270 | 4.2 | 3 | 189 | 15 | 12.6 | 13.5 | 1 | |
| 18 | | O.J. Simpson | 79.6 | 1977 | BUF | 7 | 557 | 126 | 4.4 | 0 | 138 | 16 | 8.6 | 19.7 | 0 | |
| 19 | | C. Gilchrist | 78.3 | 1962 | BUF | 14 | 1,096 | 214 | 5.1 | 13 | 319 | 24 | 13.3 | 22.8 | 2 | |
| 20 | | W. McGahee | 77.9 | 2005 | BUF | 16 | 1,247 | 325 | 3.8 | 5 | 178 | 28 | 37 | 6.4 | 11.1 | 0 |
| 21 | | C.J. Spiller | 77.8 | 2012 | BUF | 16 | 1,244 | 207 | 6.0 | 6 | 459 | 43 | 57 | 10.7 | 28.7 | 2 |
| 22 | | T. Thomas | 77.8 | 1989 | BUF | 16 | 1,244 | 298 | 4.2 | 6 | 669 | 60 | 11.2 | 41.8 | 6 | |
| 23 | | L. McCoy | 74.6 | 2015 | BUF | 12 | 895 | 203 | 4.4 | 3 | 292 | 32 | 50 | 9.1 | 24.3 | 2 |
| 24 | | J. Cribbs | 74.1 | 1980 | BUF | 16 | 1,185 | 306 | 3.9 | 11 | 415 | 52 | 8.0 | 25.9 | 1 | |
| 25 | | J. Cribbs | 73.1 | 1981 | BUF | 15 | 1,097 | 257 | 4.3 | 3 | 603 | 40 | 15.1 | 40.2 | 7 | |
StatMuse has season-level data for rushing yards per game going back to the 1932 season.
More Bills Stats
Team Rankings
PPG
28.3
5th
OPP PPG
22.9
17th
RUSH YDS/G
147.2
1st
PASS YDS/G
251.2
11th
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