most rushing yards vs patriots individual game

O.J. Simpson has the most rushing yards in a game versus the Patriots, with 250 yards on September 16, 1973.

Interpreted as:
most rushing yards by a player vs patriots individual regular-season game
NAMERUSH YDSDATETMOPPATTYPCRUSH TDREC YDSRECTRGAVGREC TD
1O.J. Simpson
O.J. Simpson
250
9/16/1973
@
29
8.6
2
0
0
0
2Knowshon Moreno
K. Moreno
224
11/24/2013
@
37
6.1
1
6
1
1
6.0
0
3O.J. Simpson
O.J. Simpson
219
12/9/1973
vs
22
10.0
1
0
0
0
4LaDainian Tomlinson
L. Tomlinson
217
9/29/2002
vs
27
8.0
2
20
4
6
5.0
0
5Greg Bell
G. Bell
210
12/24/1989
@
26
8.1
1
0
0
0
6Mercury Morris
M. Morris
197
9/30/1973
vs
15
13.1
3
0
0
0
7Harold Green
H. Green
190
12/20/1992
vs
31
6.1
1
0
0
0
8Ricky Williams
R. Williams
185
12/29/2002
@
31
6.0
2
7
2
3
3.5
0
9O.J. Simpson
O.J. Simpson
185
12/14/1975
@
21
8.8
1
28
2
14.0
0
10Peyton Hillis
P. Hillis
184
11/7/2010
vs
29
6.3
2
36
3
3
12.0
0
11Priest Holmes
P. Holmes
180
9/22/2002
@
30
6.0
2
18
5
5
3.6
1
12Breece Hall
B. Hall
178
1/7/2024
@
37
4.8
1
12
2
2
6.0
0
13Chris Warren
C. Warren
174
9/19/1993
@
36
4.8
1
0
0
0
14Herschel Walker
H. Walker
173
11/15/1987
@
28
6.2
1
59
5
11.8
0
15Cam Akers
C. Akers
171
12/10/2020
vs
29
5.9
0
23
2
3
11.5
0
16Terrell Davis
T. Davis
171
10/6/1997
vs
32
5.3
2
7
2
3.5
0
17Jonathan Taylor
J. Taylor
170
12/18/2021
vs
29
5.9
1
0
0
0
0
18Richard Huntley
R. Huntley
168
1/6/2002
vs
21
8.0
0
23
2
3
11.5
0
19John Riggins
J. Riggins
168
10/15/1972
@
32
5.3
1
0
0
0
20Thurman Thomas
T. Thomas
165
11/18/1990
vs
22
7.5
2
5
1
5.0
0
21James Brooks
J. Brooks
163
12/7/1986
@
18
9.1
1
101
6
16.8
0
22Tony Dorsett
T. Dorsett
162
9/21/1981
@
19
8.5
1
22
4
5.5
0
23Sammie Smith
S. Smith
159
9/9/1990
@
23
6.9
1
0
0
0
24Rueben Mayes
R. Mayes
157
11/30/1986
vs
33
4.8
1
25
2
12.5
0
25Roland Hooks
R. Hooks
155
11/6/1977
@
27
5.7
0
0
0
0
Results may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.

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Last Game
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Sat 17 Jan 2026

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