Mario Williams has the most sacks for the Bills in a game, with 4.5 sacks versus the Panthers on September 15, 2013.
Interpreted as:
most defensive sacks by a bills player in a regular-season game| NAME | SCK | DATE | TM | OPP | TKL | AST | COMB | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | M. Williams | 4.5 | 9/15/2013 | vs | 5 | 1 | 6 | 24.5 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 2 |  | B. Smith | 4.0 | 9/18/1994 | @ | 0 | 0 | 0 | 0 | ||||||||
| 3 | | B. Smith | 4.0 | 12/9/1990 | @ | 0 | 0 | 0 | 0 | ||||||||
| 4 | | C. Bennett | 4.0 | 12/27/1987 | @ | 0 | 0 | 0 | 0 | ||||||||
| 5 | | M. Williams | 3.5 | 11/13/2014 | @ | 4 | 1 | 5 | 21 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 6 | | G. Rousseau | 3.0 | 9/8/2024 | vs | 6 | 0 | 6 | 11 | 0 | 0 | 0 | 1 | 0 | 0 | ||
| 7 | | J. Phillips | 3.0 | 10/6/2019 | @ | 3 | 0 | 3 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 8 | | L. Alexander | 3.0 | 10/9/2016 | @ | 7 | 0 | 7 | 19 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 9 | | M. Dareus | 3.0 | 11/9/2014 | vs | 4 | 3 | 7 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 10 | | M. Dareus | 3.0 | 10/5/2014 | @ | 5 | 0 | 5 | 18 | 0 | 0 | 0 | 1 | 0 | 0 | ||
| 11 | | M. Williams | 3.0 | 11/25/2012 | @ | 3 | 0 | 3 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 12 | | C. Kelsay | 3.0 | 12/24/2011 | vs | 7 | 3 | 10 | 27 | 0 | 0 | 0 | 1 | 0 | 0 | ||
| 13 | | A. Schobel | 3.0 | 12/27/2009 | @ | 4 | 0 | 4 | 16 | 0 | 0 | 0 | 2 | 0 | 0 | ||
| 14 | | A. Schobel | 3.0 | 12/10/2006 | @ | 6 | 3 | 9 | 31 | 0 | 0 | 0 | 1 | 0 | 0 | ||
| 15 | | R. Denney | 3.0 | 9/17/2006 | @ | 4 | 0 | 4 | 33 | 0 | 0 | 0 | 1 | 0 | 0 | ||
| 16 | | L. Milloy | 3.0 | 11/21/2004 | vs | 6 | 0 | 6 | 22 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 17 | | A. Schobel | 3.0 | 11/30/2003 | @ | 5 | 0 | 5 | 18 | 0 | 0 | 0 | 0 | 1 | 0 | ||
| 18 | | P. Williams | 3.0 | 12/6/1998 | @ | 0 | 0 | 0 | 0 | ||||||||
| 19 | | B. Paup | 3.0 | 9/7/1997 | @ | 0 | 0 | 0 | 0 | ||||||||
| 20 | | B. Smith | 3.0 | 9/8/1996 | vs | 0 | 0 | 0 | 0 | ||||||||
| 21 | | B. Smith | 3.0 | 12/3/1995 | @ | 0 | 0 | 0 | 0 | ||||||||
| 22 | | B. Paup | 3.0 | 11/5/1995 | @ | 0 | 0 | 0 | 0 | ||||||||
| 23 | | B. Paup | 3.0 | 9/17/1995 | vs | 0 | 0 | 0 | 0 | ||||||||
| 24 | | B. Smith | 3.0 | 9/20/1992 | vs | 0 | 0 | 0 | 0 | ||||||||
| 25 | | B. Smith | 3.0 | 10/22/1989 | vs | 0 | 0 | 0 | 0 | ||||||||
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SFStatMuse has game-level data for sacks going back to the 1982 season.
More Bills Stats
Team Leaders 
PASS
3,276
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RUSH
1,415
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REC
650
Shakir
Team Rankings
PPG
29.4
3rd
OPP PPG
23.1
16th
RUSH YDS/G
158.5
1st
PASS YDS/G
237.9
11th
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NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
11 | 3 | 0 | .786 | |
10 | 4 | 0 | .714 | |
 Dolphins - e | 6 | 8 | 0 | .429 |
 Jets - e | 3 | 11 | 0 | .214 |
| AFC North | W | L | T | PCT |
8 | 6 | 0 | .571 | |
7 | 7 | 0 | .500 | |
 Bengals - e | 4 | 10 | 0 | .286 |
 Browns - e | 3 | 11 | 0 | .214 |
| AFC South | W | L | T | PCT |
10 | 4 | 0 | .714 | |
9 | 5 | 0 | .643 | |
8 | 6 | 0 | .571 | |
 Titans - e | 2 | 12 | 0 | .143 |
| AFC West | W | L | T | PCT |
 Broncos - x | 12 | 2 | 0 | .857 |
10 | 4 | 0 | .714 | |
 Chiefs - e | 6 | 8 | 0 | .429 |
 Raiders - e | 2 | 12 | 0 | .143 |
Steelers
Ravens
Jaguars
Texans
Chargers| NFC East | W | L | T | PCT |
|---|---|---|---|---|
9 | 5 | 0 | .643 | |
6 | 7 | 1 | .464 | |
 Commanders - e | 4 | 10 | 0 | .286 |
 Giants - e | 2 | 12 | 0 | .143 |
| NFC North | W | L | T | PCT |
10 | 4 | 0 | .714 | |
9 | 4 | 1 | .679 | |
8 | 6 | 0 | .571 | |
 Vikings - e | 6 | 8 | 0 | .429 |
| NFC South | W | L | T | PCT |
7 | 7 | 0 | .500 | |
7 | 7 | 0 | .500 | |
 Falcons - e | 5 | 9 | 0 | .357 |
 Saints - e | 4 | 10 | 0 | .286 |
| NFC West | W | L | T | PCT |
 Rams - x | 11 | 3 | 0 | .786 |
11 | 3 | 0 | .786 | |
10 | 4 | 0 | .714 | |
 Cardinals - e | 3 | 11 | 0 | .214 |
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Bears
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Buccaneers
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