The San Francisco 49ers had their most sacks in a game on November 23, 1980, on October 11, 1976 and on December 6, 1964, with 10 sacks.
Interpreted as:
most defensive sacks in 49ers regular-season game| TEAM | SCK | DATE | TM | OPP | RESULT | TKL | AST | COMB | SCKY | INT | INT YDS | INT TD | FF | FR | FR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 10.0 | 11/23/1980 | vs | W 12-0 | 67 | 1 | 13 | 0 | 0 | 0 | ||||||
| 2 | | 49ers | 10.0 | 10/11/1976 | @ | W 16-0 | 97 | 0 | 0 | 0 | 3 | 0 | ||||||
| 3 | | 49ers | 10.0 | 12/6/1964 | vs | W 28-7 | 62 | 2 | 52 | 0 | 2 | 0 | ||||||
| 4 | | 49ers | 9.0 | 10/29/1989 | @ | W 23-10 | 82 | 0 | 0 | 0 | 2 | 0 | ||||||
| 5 | | 49ers | 9.0 | 9/22/1985 | @ | W 34-10 | 71 | 2 | 33 | 0 | 1 | 1 | ||||||
| 6 | | 49ers | 9.0 | 11/13/1983 | vs | W 27-0 | 77 | 2 | 10 | 0 | 1 | 0 | ||||||
| 7 | | 49ers | 9.0 | 11/23/1972 | @ | W 31-10 | 66 | 2 | 23 | 1 | 2 | 1 | ||||||
| 8 | | 49ers | 8.0 | 11/1/2018 | vs | W 34-3 | 46 | 4 | 50 | 39 | 0 | 0 | 0 | 2 | 0 | 0 | ||
| 9 | | 49ers | 8.0 | 1/3/2010 | @ | W 28-6 | 55 | 2 | 57 | 58 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 10 | | 49ers | 8.0 | 10/25/1998 | @ | W 28-10 | 32 | 3 | 36 | 0 | 1 | 0 | ||||||
| 11 | | 49ers | 8.0 | 11/10/1997 | @ | W 24-12 | 43 | 1 | 10 | 0 | 2 | 1 | ||||||
| 12 | | 49ers | 8.0 | 11/23/1986 | vs | W 20-0 | 80 | 1 | 0 | 0 | 0 | 0 | ||||||
| 13 | | 49ers | 8.0 | 11/25/1984 | @ | W 35-3 | 48 | 1 | 53 | 1 | 0 | 0 | ||||||
| 14 | | 49ers | 8.0 | 9/25/1983 | vs | W 24-20 | 59 | 0 | 0 | 0 | 1 | 0 | ||||||
| 15 | | 49ers | 8.0 | 10/23/1977 | vs | W 28-7 | 67 | 2 | 80 | 0 | 0 | 0 | ||||||
| 16 | | 49ers | 8.0 | 10/23/1976 | vs | W 15-0 | 85 | 2 | 18 | 0 | 1 | 0 | ||||||
| 17 | | 49ers | 8.0 | 9/26/1971 | @ | W 38-20 | 49 | 1 | 0 | 0 | 1 | 0 | ||||||
| 18 | | 49ers | 8.0 | 12/16/1967 | vs | W 24-16 | 54 | 2 | 22 | 0 | 2 | 0 | ||||||
| 19 | | 49ers | 8.0 | 9/24/1967 | vs | W 38-7 | 75 | 1 | 0 | 0 | 0 | 0 | ||||||
| 20 | | 49ers | 8.0 | 11/1/1959 | vs | W 33-7 | 75 | 0 | 2 | 0 | ||||||||
| 21 | | 49ers | 8.0 | 12/11/1954 | vs | W 10-7 | 68 | 0 | 1 | 0 | ||||||||
| 22 | | 49ers | 8.0 | 9/26/1954 | vs | W 41-7 | 72 | 1 | 3 | 0 | ||||||||
| 23 | | 49ers | 7.0 | 12/8/2024 | vs | W 38-13 | 40 | 16 | 56 | 46 | 0 | 0 | 0 | 0 | 1 | 0 | ||
| 24 | | 49ers | 7.0 | 10/3/2022 | vs | W 24-9 | 50 | 18 | 68 | 54 | 1 | 52 | 1 | 1 | 1 | 0 | ||
| 25 | | 49ers | 7.0 | 10/27/2019 | vs | W 51-13 | 49 | 9 | 58 | 58 | 3 | 70 | 0 | 0 | 0 | 0 | ||
LA
STL
BAL
WASResults may be incomplete. StatMuse has complete team, game-level data for sacks going back to the 1952 season.
More 49ers Stats
Team Leaders 
PASS
402
Purdy
RUSH
83
McCaffrey
REC
112
Robinson
Team Rankings
PPG
25.7
10th
OPP PPG
21.8
13th
RUSH YDS/G
106.9
24th
PASS YDS/G
254.0
6th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
