Santonio Holmes scored his most total touchdowns in a game on November 21, 2010, on November 5, 2007 and on September 30, 2007, with 2 touchdowns.
Interpreted as:
most touchdowns by Santonio Holmes in a regular-season game| NAME | TD | DATE | TM | OPP | RUSH TD | REC TD | RET TD | FGM | XPM | XP2 | SFTY | PTS | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | S. Holmes | 2 | 11/21/2010 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 2 | | S. Holmes | 2 | 11/5/2007 | vs | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 3 | | S. Holmes | 2 | 9/30/2007 | @ | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 12 | ||
| 4 | | S. Holmes | 1 | 9/22/2013 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 5 | | S. Holmes | 1 | 9/16/2012 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 6 | | S. Holmes | 1 | 12/18/2011 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 7 | | S. Holmes | 1 | 12/11/2011 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 8 | | S. Holmes | 1 | 12/4/2011 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 9 | | S. Holmes | 1 | 11/27/2011 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 10 | | S. Holmes | 1 | 11/6/2011 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 11 | | S. Holmes | 1 | 10/17/2011 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 12 | | S. Holmes | 1 | 10/9/2011 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 13 | | S. Holmes | 1 | 9/18/2011 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 14 | | S. Holmes | 1 | 1/2/2011 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 15 | | S. Holmes | 1 | 12/26/2010 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 16 | | S. Holmes | 1 | 11/25/2010 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 17 | | S. Holmes | 1 | 11/14/2010 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 18 | | S. Holmes | 1 | 1/3/2010 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 19 | | S. Holmes | 1 | 12/27/2009 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 20 | | S. Holmes | 1 | 12/6/2009 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 21 | | S. Holmes | 1 | 11/29/2009 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 22 | | S. Holmes | 1 | 9/10/2009 | vs | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 23 | | S. Holmes | 1 | 12/21/2008 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 24 | | S. Holmes | 1 | 12/14/2008 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
| 25 | | S. Holmes | 1 | 11/30/2008 | @ | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 6 | ||
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CHIResults may be incomplete. StatMuse has complete game-level data for touchdowns going back to the 1950 season.
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| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
