James Cook III had the most all-purpose yards for the Bills in a game this season, with 216 yards against the Panthers on October 26.
Interpreted as:
most yards in regular-season game by bills player this season| NAME | YDS | DATE | TM | OPP | TD | RUSH YDS | RUSH TD | REC YDS | REC TD | KR YDS | KR TD | PR YDS | PR TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | J. Cook III | 216 | 10/26/2025 | @ | 2 | 216 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 2 |  | R. Davis | 196 | 1/4/2026 | vs | 1 | 151 | 0 | 23 | 1 | 22 | 0 | 0 | 0 | ||
| 3 | | R. Davis | 177 | 12/14/2025 | @ | 0 | 0 | 0 | 13 | 0 | 164 | 0 | 0 | 0 | ||
| 4 | | J. Cook III | 177 | 11/30/2025 | @ | 0 | 144 | 0 | 33 | 0 | 0 | 0 | 0 | 0 | ||
| 5 | | R. Davis | 158 | 11/16/2025 | vs | 0 | 0 | 0 | 0 | 0 | 158 | 0 | 0 | 0 | ||
| 6 | | R. Davis | 145 | 11/20/2025 | @ | 1 | 0 | 0 | 0 | 0 | 145 | 1 | 0 | 0 | ||
| 7 | | B. Codrington | 139 | 9/7/2025 | vs | 0 | 0 | 0 | 0 | 0 | 139 | 0 | 0 | 0 | ||
| 8 | | B. Codrington | 135 | 10/13/2025 | @ | 0 | 0 | 0 | 0 | 0 | 114 | 0 | 21 | 0 | ||
| 9 | | J. Cook III | 135 | 9/28/2025 | vs | 1 | 117 | 1 | 18 | 0 | 0 | 0 | 0 | 0 | ||
| 10 | | J. Cook III | 135 | 9/14/2025 | @ | 2 | 132 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | ||
| 11 | | J. Cook III | 134 | 12/21/2025 | @ | 2 | 117 | 2 | 17 | 0 | 0 | 0 | 0 | 0 | ||
| 12 | | J. Cook III | 129 | 11/20/2025 | @ | 1 | 116 | 1 | 13 | 0 | 0 | 0 | 0 | 0 | ||
| 13 | | R. Davis | 126 | 12/21/2025 | @ | 0 | 14 | 0 | 20 | 0 | 92 | 0 | 0 | 0 | ||
| 14 |  | K. Shakir | 125 | 11/20/2025 | @ | 0 | 0 | 0 | 110 | 0 | 0 | 0 | 15 | 0 | ||
| 15 | | J. Cook III | 125 | 11/2/2025 | vs | 0 | 114 | 0 | 11 | 0 | 0 | 0 | 0 | 0 | ||
| 16 | | J. Cook III | 118 | 9/18/2025 | vs | 1 | 108 | 1 | 10 | 0 | 0 | 0 | 0 | 0 | ||
| 17 | | J. Cook III | 114 | 11/16/2025 | vs | 1 | 48 | 0 | 66 | 1 | 0 | 0 | 0 | 0 | ||
| 18 | | K. Coleman | 112 | 9/7/2025 | vs | 1 | 0 | 0 | 112 | 1 | 0 | 0 | 0 | 0 | ||
| 19 | | J. Cook III | 111 | 12/14/2025 | @ | 3 | 107 | 2 | 4 | 1 | 0 | 0 | 0 | 0 | ||
| 20 | | J. Cook III | 111 | 12/7/2025 | vs | 0 | 80 | 0 | 31 | 0 | 0 | 0 | 0 | 0 | ||
| 21 |  | C. Samuel | 110 | 10/5/2025 | vs | 1 | 0 | 0 | 26 | 1 | 84 | 0 | 0 | 0 | ||
| 22 | | B. Codrington | 110 | 9/18/2025 | vs | 0 | 0 | 0 | 0 | 0 | 95 | 0 | 15 | 0 | ||
| 23 |  | D. Kincaid | 108 | 10/5/2025 | vs | 0 | 0 | 0 | 108 | 0 | 0 | 0 | 0 | 0 | ||
| 24 | | R. Davis | 105 | 11/2/2025 | vs | 0 | 0 | 0 | 0 | 0 | 105 | 0 | 0 | 0 | ||
| 25 | | J. Cook III | 102 | 9/7/2025 | vs | 1 | 44 | 1 | 58 | 0 | 0 | 0 | 0 | 0 | ||
More Bills Stats
Team Leaders 
PASS
556
Allen
RUSH
163
Cook
REC
157
Shakir
Team Rankings
PPG
28.3
4th
OPP PPG
21.5
12th
RUSH YDS/G
159.6
1st
PASS YDS/G
234.2
13th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - y | 14 | 3 | 0 | .824 |
 Bills - w | 12 | 5 | 0 | .706 |
 Dolphins - e | 7 | 10 | 0 | .412 |
 Jets - e | 3 | 14 | 0 | .176 |
| AFC North | W | L | T | PCT |
 Steelers - y | 10 | 7 | 0 | .588 |
 Ravens - e | 8 | 9 | 0 | .471 |
 Bengals - e | 6 | 11 | 0 | .353 |
 Browns - e | 5 | 12 | 0 | .294 |
| AFC South | W | L | T | PCT |
 Jaguars - y | 13 | 4 | 0 | .765 |
 Texans - w | 12 | 5 | 0 | .706 |
 Colts - e | 8 | 9 | 0 | .471 |
 Titans - e | 3 | 14 | 0 | .176 |
| AFC West | W | L | T | PCT |
 Broncos - z* | 14 | 3 | 0 | .824 |
 Chargers - w | 11 | 6 | 0 | .647 |
 Chiefs - e | 6 | 11 | 0 | .353 |
 Raiders - e | 3 | 14 | 0 | .176 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 11 | 6 | 0 | .647 |
 Cowboys - e | 7 | 9 | 1 | .441 |
 Commanders - e | 5 | 12 | 0 | .294 |
 Giants - e | 4 | 13 | 0 | .235 |
| NFC North | W | L | T | PCT |
 Bears - y | 11 | 6 | 0 | .647 |
 Packers - w | 9 | 7 | 1 | .559 |
 Vikings - e | 9 | 8 | 0 | .529 |
 Lions - e | 9 | 8 | 0 | .529 |
| NFC South | W | L | T | PCT |
 Panthers - y | 8 | 9 | 0 | .471 |
 Buccaneers - e | 8 | 9 | 0 | .471 |
 Falcons - e | 8 | 9 | 0 | .471 |
 Saints - e | 6 | 11 | 0 | .353 |
| NFC West | W | L | T | PCT |
 Seahawks - z* | 14 | 3 | 0 | .824 |
 Rams - w | 12 | 5 | 0 | .706 |
 49ers - w | 12 | 5 | 0 | .706 |
 Cardinals - e | 3 | 14 | 0 | .176 |
