Thurman Thomas rushed for his most yards in a game against the Jets on September 24, 1990, with 214 yards.
- All-time
- Regular season
| NAME | RUSH YDS | DATE | TM | OPP | ATT | YPC | RUSH TD | REC YDS | REC | TRG | AVG | REC TD | |||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | T. Thomas | 214 | 9/24/1990 | @ | 18 | 11.9 | 0 | 5 | 3 | 1.7 | 0 | |||
| 2 | | T. Thomas | 165 | 9/1/1991 | vs | 25 | 6.6 | 1 | 103 | 8 | 12.9 | 1 | |||
| 3 | | T. Thomas | 165 | 11/18/1990 | vs | 22 | 7.5 | 2 | 5 | 1 | 5.0 | 0 | |||
| 4 | | T. Thomas | 155 | 11/8/1992 | vs | 37 | 4.2 | 1 | 30 | 4 | 7.5 | 0 | |||
| 5 | | T. Thomas | 154 | 12/23/1990 | vs | 30 | 5.1 | 1 | 29 | 2 | 14.5 | 0 | |||
| 6 | | T. Thomas | 148 | 12/17/1995 | vs | 35 | 4.2 | 1 | 11 | 1 | 11.0 | 1 | |||
| 7 | | T. Thomas | 148 | 10/29/1989 | vs | 27 | 5.5 | 1 | 21 | 2 | 10.5 | 0 | |||
| 8 | | T. Thomas | 142 | 10/26/1992 | @ | 21 | 6.8 | 0 | 22 | 3 | 7.3 | 1 | |||
| 9 | | T. Thomas | 136 | 10/28/1990 | @ | 22 | 6.2 | 1 | 9 | 1 | 9.0 | 0 | |||
| 10 | | T. Thomas | 135 | 11/18/1991 | @ | 23 | 5.9 | 1 | 40 | 3 | 13.3 | 1 | |||
| 11 | | T. Thomas | 133 | 10/8/1995 | vs | 27 | 4.9 | 1 | 4 | 1 | 4.0 | 0 | |||
| 12 | | T. Thomas | 129 | 12/10/1995 | @ | 24 | 5.4 | 0 | 16 | 3 | 5.3 | 1 | |||
| 13 | | T. Thomas | 129 | 11/1/1993 | vs | 28 | 4.6 | 1 | 1 | 1 | 1.0 | 0 | |||
| 14 | | T. Thomas | 127 | 11/12/1989 | vs | 29 | 4.4 | 0 | 21 | 2 | 10.5 | 1 | |||
| 15 | | T. Thomas | 126 | 11/3/1991 | vs | 32 | 3.9 | 1 | 32 | 1 | 32.0 | 0 | |||
| 16 | | T. Thomas | 125 | 10/9/1994 | vs | 31 | 4.0 | 2 | 1 | 1 | 1.0 | 0 | |||
| 17 | | T. Thomas | 124 | 12/1/1991 | vs | 23 | 5.4 | 0 | 33 | 4 | 8.3 | 0 | |||
| 18 | | T. Thomas | 122 | 10/3/1993 | vs | 26 | 4.7 | 0 | 21 | 3 | 7.0 | 0 | |||
| 19 | | T. Thomas | 120 | 12/12/1992 | vs | 26 | 4.6 | 1 | 39 | 3 | 13.0 | 0 | |||
| 20 | | T. Thomas | 120 | 9/27/1992 | @ | 18 | 6.7 | 1 | 27 | 2 | 13.5 | 0 | |||
| 21 | | T. Thomas | 119 | 10/27/1996 | @ | 26 | 4.6 | 1 | 0 | 0 | 0 | ||||
| 22 | | T. Thomas | 117 | 10/24/1993 | @ | 27 | 4.3 | 0 | 67 | 7 | 9.6 | 0 | |||
| 23 | | T. Thomas | 117 | 10/13/1991 | vs | 20 | 5.9 | 2 | 26 | 1 | 26.0 | 0 | |||
| 24 | | T. Thomas | 117 | 9/29/1991 | vs | 25 | 4.7 | 1 | 40 | 3 | 13.3 | 0 | |||
| 25 | | T. Thomas | 116 | 11/21/1993 | vs | 27 | 4.3 | 0 | 48 | 3 | 16.0 | 0 | |||
BUF
NYJ
MIA
NE
PIT
STL
WAS
IND
NYG
DEN
CHIResults may be incomplete. StatMuse has complete game-level data for rushing yards going back to the 1960 season.
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More Bills Stats
Team Leaders 
PASS
334
Allen
RUSH
57
Cook
REC
130
Kincaid
Team Rankings
PPG
36.0
5th
OPP PPG
31.0
23rd
RUSH YDS/G
86.0
25th
PASS YDS/G
334.0
4th
DET
LAC
LAR
LV
NFL 2026 Leaders
NFL 2026 Rankings
NFL Fantasy 2026
NFL 2026 Betting
NFL 2026 Standings
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| NFC South | W | L | T | PCT |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| NFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 |
Eagles
Commanders
Cowboys
Vikings
Bears
Packers
Falcons
Buccaneers
Saints
Panthers
49ers
Cardinals
Seahawks| AFC East | W | L | T | PCT |
|---|---|---|---|---|
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC North | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
| AFC South | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 | |
| AFC West | W | L | T | PCT |
1 | 0 | 0 | 1.000 | |
1 | 0 | 0 | 1.000 | |
0 | 1 | 0 | .000 | |
0 | 1 | 0 | .000 |
Ravens
Bengals
Browns
Jaguars
Texans
Titans
Chiefs