The San Francisco 49ers were 1-0 against the spread when the point differential was 17 or above points against the Colts on Monday.
Interpreted as:
NFL ats and points differentials the past 17 or more games| TEAM | DATE | ATS | DIFF | TM | OPP | RESULT | SPREAD | ATS DIFF | O/U | O/U DIFF | TD | 1DWN | OFF | OPP OFF | 3DWN% | 4DWN% | |||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 |  | 49ers | 12/22/2025 | 1-0 | 21 | -222 | @ | +185 | W 48-27 | -4.5 | +16.5 (Y) | 46.5 | +28.5 (O) | 6 | 28 | 440 | 312 | 63.6 | 100.0 | ||
| 2 |  | Chargers | 12/21/2025 | 1-0 | 17 | +101 | @ | -119 | W 34-17 | +1.5 | +18.5 (Y) | 50.5 | +0.5 (O) | 4 | 24 | 452 | 340 | 63.6 | 0.0 | ||
| 3 |  | Saints | 12/21/2025 | 1-0 | 23 | -306 | vs | +241 | W 29-6 | -6.5 | +16.5 (Y) | 39.5 | -4.5 (U) | 2 | 23 | 412 | 195 | 47.1 | 50.0 | ||
| 4 |  | Titans | 12/21/2025 | 1-0 | 17 | +149 | vs | -177 | W 26-9 | +3.5 | +20.5 (Y) | 37.5 | -2.5 (U) | 3 | 22 | 376 | 133 | 52.9 | 0.0 | ||
| 5 |  | Bengals | 12/21/2025 | 1-0 | 24 | -203 | @ | +169 | W 45-21 | -3.5 | +20.5 (Y) | 48.5 | +17.5 (O) | 6 | 23 | 407 | 389 | 50.0 | 100.0 | ||
| 6 |  | Ravens | 12/14/2025 | 1-0 | 24 | -169 | @ | +142 | W 24-0 | -3 | +21 (Y) | 51.5 | -27.5 (U) | 3 | 15 | 317 | 298 | 28.6 | |||
| 7 |  | Bears | 12/14/2025 | 1-0 | 28 | -391 | vs | +306 | W 31-3 | -7.5 | +20.5 (Y) | 38.5 | -4.5 (U) | 4 | 21 | 361 | 192 | 38.5 | 50.0 | ||
| 8 |  | Texans | 12/14/2025 | 1-0 | 20 | -592 | vs | +435 | W 40-20 | -10.5 | +9.5 (Y) | 42.5 | +17.5 (O) | 4 | 23 | 399 | 307 | 53.8 | |||
| 9 |  | Jaguars | 12/14/2025 | 1-0 | 28 | -1010 | vs | +634 | W 48-20 | -13.5 | +14.5 (Y) | 40.5 | +27.5 (O) | 6 | 24 | 438 | 284 | 44.4 | |||
| 10 |  | Eagles | 12/14/2025 | 1-0 | 31 | -901 | vs | +603 | W 31-0 | -12.5 | +18.5 (Y) | 37.5 | -6.5 (U) | 4 | 27 | 387 | 75 | 76.9 | 0.0 | ||
| 11 |  | Seahawks | 12/7/2025 | 1-0 | 28 | -339 | @ | +272 | W 37-9 | -6.5 | +21.5 (Y) | 45.5 | +0.5 (O) | 4 | 20 | 365 | 274 | 46.2 | |||
| 12 | | Jaguars | 12/7/2025 | 1-0 | 17 | +120 | vs | -143 | W 36-19 | +2.5 | +19.5 (Y) | 45.5 | +9.5 (O) | 4 | 18 | 350 | 285 | 46.7 | 50.0 | ||
| 13 |  | Vikings | 12/7/2025 | 1-0 | 31 | -112 | vs | -107 | W 31-0 | +1.5 | +32.5 (Y) | 43.5 | -12.5 (U) | 4 | 25 | 313 | 206 | 54.5 | 100.0 | ||
| 14 |  | Dolphins | 12/7/2025 | 1-0 | 24 | -148 | @ | +124 | W 34-10 | -2.5 | +21.5 (Y) | 41 | +3 (O) | 4 | 23 | 358 | 207 | 20.0 | |||
| 15 |  | Rams | 12/7/2025 | 1-0 | 28 | -505 | @ | +365 | W 45-17 | -9.5 | +18.5 (Y) | 48.5 | +13.5 (O) | 6 | 30 | 530 | 314 | 37.5 | |||
| 16 |  | Patriots | 12/1/2025 | 1-0 | 18 | -372 | vs | +293 | W 33-15 | -7.5 | +10.5 (Y) | 46.5 | +1.5 (O) | 3 | 21 | 395 | 239 | 46.2 | 100.0 | ||
| 17 | | Jaguars | 11/30/2025 | 1-0 | 22 | -280 | @ | +228 | W 25-3 | -6 | +16 (Y) | 42.5 | -14.5 (U) | 3 | 20 | 272 | 188 | 23.1 | 100.0 | ||
| 18 | | 49ers | 11/30/2025 | 1-0 | 18 | -250 | @ | +204 | W 26-8 | -5.5 | +12.5 (Y) | 35.5 | -1.5 (U) | 3 | 19 | 252 | 253 | 64.7 | |||
| 19 | | Seahawks | 11/30/2025 | 1-0 | 26 | -893 | vs | +572 | W 26-0 | -12.5 | +13.5 (Y) | 41.5 | -15.5 (U) | 2 | 17 | 219 | 162 | 40.0 | 100.0 | ||
| 20 |  | Bills | 11/30/2025 | 1-0 | 19 | -175 | @ | +145 | W 26-7 | -3 | +16 (Y) | 44.5 | -11.5 (U) | 3 | 26 | 372 | 166 | 53.3 | 100.0 | ||
| 21 | | Chargers | 11/30/2025 | 1-0 | 17 | -543 | vs | +403 | W 31-14 | -9.5 | +7.5 (Y) | 40.5 | +4.5 (O) | 4 | 22 | 341 | 156 | 70.6 | 0.0 | ||
| 22 | | Bengals | 11/27/2025 | 1-0 | 18 | +325 | @ | -435 | W 32-14 | +7.5 | +25.5 (Y) | 52.5 | -6.5 (U) | 2 | 22 | 382 | 346 | 42.1 | 50.0 | ||
| 23 |  | Packers | 11/23/2025 | 1-0 | 17 | -285 | vs | +232 | W 23-6 | -6.5 | +10.5 (Y) | 41.5 | -12.5 (U) | 2 | 22 | 288 | 145 | 50.0 | |||
| 24 | | Rams | 11/23/2025 | 1-0 | 27 | -373 | vs | +295 | W 34-7 | -7 | +20 (Y) | 49.5 | -8.5 (U) | 4 | 20 | 333 | 193 | 40.0 | 0.0 | ||
| 25 |  | Cowboys | 11/17/2025 | 1-0 | 17 | -202 | @ | +166 | W 33-16 | -3.5 | +13.5 (Y) | 48.5 | +0.5 (O) | 4 | 24 | 381 | 236 | 40.0 | 33.3 | ||
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TBResults may be incomplete. StatMuse has complete team, game-level data for spread records going back to the 1979 season.
More 49ers Stats
Team Leaders 
PASS
2,151
Jones
RUSH
1,039
McCaffrey
REC
849
McCaffrey
Team Rankings
PPG
26.1
9th
OPP PPG
21.3
12th
RUSH YDS/G
104.3
25th
PASS YDS/G
259.2
5th
NFL 2025 Leaders
NFL 2025 Rankings
NFL Fantasy 2025
NFL 2025 Betting
NFL 2025 Standings
| AFC East | W | L | T | PCT |
|---|---|---|---|---|
 Patriots - x | 12 | 3 | 0 | .800 |
 Bills - x | 11 | 4 | 0 | .733 |
 Dolphins - e | 6 | 9 | 0 | .400 |
 Jets - e | 3 | 12 | 0 | .200 |
| AFC North | W | L | T | PCT |
9 | 6 | 0 | .600 | |
7 | 8 | 0 | .467 | |
 Bengals - e | 5 | 10 | 0 | .333 |
 Browns - e | 3 | 12 | 0 | .200 |
| AFC South | W | L | T | PCT |
 Jaguars - x | 11 | 4 | 0 | .733 |
10 | 5 | 0 | .667 | |
8 | 7 | 0 | .533 | |
 Titans - e | 3 | 12 | 0 | .200 |
| AFC West | W | L | T | PCT |
 Broncos - x | 13 | 3 | 0 | .813 |
 Chargers - x | 11 | 4 | 0 | .733 |
 Chiefs - e | 6 | 10 | 0 | .375 |
 Raiders - e | 2 | 13 | 0 | .133 |
| NFC East | W | L | T | PCT |
|---|---|---|---|---|
 Eagles - y | 10 | 5 | 0 | .667 |
 Cowboys - e | 7 | 8 | 1 | .469 |
 Commanders - e | 4 | 12 | 0 | .250 |
 Giants - e | 2 | 13 | 0 | .133 |
| NFC North | W | L | T | PCT |
 Bears - x | 11 | 4 | 0 | .733 |
 Packers - x | 9 | 5 | 1 | .633 |
 Vikings - e | 8 | 8 | 0 | .500 |
 Lions - e | 8 | 8 | 0 | .500 |
| NFC South | W | L | T | PCT |
8 | 7 | 0 | .533 | |
7 | 8 | 0 | .467 | |
 Falcons - e | 6 | 9 | 0 | .400 |
 Saints - e | 5 | 10 | 0 | .333 |
| NFC West | W | L | T | PCT |
 Seahawks - x | 12 | 3 | 0 | .800 |
 49ers - x | 11 | 4 | 0 | .733 |
 Rams - x | 11 | 4 | 0 | .733 |
 Cardinals - e | 3 | 12 | 0 | .200 |
Panthers
